Results 81 to 90 of about 112,322 (317)

Use of monitoring indicators in hospital management of antimicrobials

BMC Infectious Diseases, 2021
Background According to the literature, 25% to 50% of antimicrobials prescribed in hospitals are unnecessary or inappropriate, directly impacting antimicrobial resistance.
Ravena Melo Ribeiro da Silva, Simonize Cunha B. de Mendonça, Ingrid Novaes Leão, Quesia Nery dos Santos, Alessandra Macedo Batista, Matheus Santos Melo, Milena da Motta Xavier, Lucindo José Quintans Júnior, Wellington Barros da Silva, Iza Maria Fraga Lobo   +9 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

MEDICAL PROTECTION FOR THE EXPEDITIONARY FORCE IN THE EVENT OF USING BIOLOGICAL AGENTS [PDF]

Annals: Series on Military Sciences, 2014
The ADM/CBRN military or terrorist attack is most likely to be enforced on the force deployed in the theaters of operations (TO), as peace making troops, peace keeping troops, etc.
Viorel ORDEANUL, Simona BICHERU, Gabriela DUMITRESCU   +2 more
doaj  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Evidence for antibiotic induced Clostridium perfringens diarrhoea [PDF]

, 2001
Clostridium difficile is a well documented cause of antibiotic associated diarrhoea in hospitalised patients, but may account for only approximately 20% of all cases.
Modi, N., Wilcox, M.H.
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]

, 2016
Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo, A Morello, A Morillo, Arturo Ferreira, B Berwin, C Junqueira, C Ribeiro, C Valck, Carlos González, Carlos Rosas, E Sosoniuk, FJ Sánchez, FJ Sánchez, G Ramirez, G Ramírez, G Ramírez, Galia Ramírez, H Adachi, Ismael Maldonado, J Canton, J Clayton, Javier Pizarro-Bauerle, JC Aguillon, JC Aguillon, JD Maya, Jorge Ferreira, K Ahn, L Aguilar, L Aguilar, L Ubillos, Lorena Aguilar-Guzmán, M Michalak, M Obeid, M Pavani, MF Festing, NC López, Paula Abello-Cáceres, R Ramos, RH Berg Van den, V Ferreira, V Toledo, VD Kallinikova, Z Batmonkh   +42 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

ESC core curriculum for the general cardiologist (2013) [PDF]

, 2013
[No abstract ...
A. Kitsiou, A. L. P. Caforio, A. Porta-Sanchez, A. Vahanian, B. Iung, C. Carrera, C. Szymanski, D. Herpin, D. Taggart, F. Calvo, F. Flachskampf, G. Ertl, G. Iaccarino, H. Burri, I. J. Nunez, J. Bauersachs, J. Bax, J. Hall, J. J. Monsuez, J. Lopez-Sendon, J. P. Schmid, J. R. Gonzalez-Juanatey, J. Stepinska, K. Zeppenfeld, L. Goncalves, L. Joubert, L. M. Ruilope, L. Tokgozoglu, M. J. Salvador, M. Sousa-Ouva, M. Tendera, N. Brooks, null null, null null, null null, null null, null null, null null, null null, O. A. Smiseth, P. A. Sirnes, P. Charron, P. Giannuzzi, P. Gueret, P. Kearney, P. Lancellotti, P. Trindade, R. B. A. van den Brink, R. Fontes-Carvalho, R. Griebenow, S. Gibbs, S. Plein, S. Price, S. Priori, T. C. Gillebert, T. McDonough, V. Regitz-Zagrosek, Z. Fras, Z. Reiner   +58 more
core   +2 more sources

Curcumin Mediated Gold Nanoparticles and Analysis of its Antioxidant, Anti-inflammatory, Antimicrobial Activity Against Oral Pathogens

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To green synthesise gold nanoparticles using curcumin and to analyse its antioxidant, anti-inflammatory, and antimicrobial activity among oral pathogens.
Sreedevi Dharman, Gopal Maragathavalli, Rajeshkumar Shanmugam, Karpagavalli Shanmugasundaram   +3 more
doaj