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Toxicity and Anti-Inflammatory Activity of Phenolic-Rich Extract from Nopalea cochenillifera (Cactaceae): A Preclinical Study on the Prevention of Inflammatory Bowel Diseases

open access: yesPlants, 2023
Phenolic compounds have been scientifically recognized as beneficial to intestinal health. The cactus Nopalea cochenillifera, used as anti-inflammatory in traditional medicine, is a rich source of these bioactive compounds.
Emanuella de Aragão Tavares   +12 more
semanticscholar   +1 more source

Flavonoids as Potential Anti-Inflammatory Molecules: A Review

open access: yesMolecules, 2022
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits, cereals, nuts, herbs, seeds, stems, and flowers of numerous plants.
J. M. Al-Khayri   +5 more
semanticscholar   +1 more source

sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis

open access: yesStem Cell Research & Therapy, 2021
Background Tumor necrosis factor (TNF)-α inhibitors represented by Etanercept (a fusion protein containing soluble TNF receptor II (sTNFRII) and the Fc segment of human IgG1) play a pivotal role in Rheumatoid arthritis (RA) treatment.
Yingjie Zhao   +9 more
doaj   +1 more source

Are statins anti-inflammatory? [PDF]

open access: yesTrials, 2000
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the basis of lipid lowering alone. Emerging evidence from both clinical trials and basic science studies suggest that statins have anti ...
Blake, Gavin J., Ridker, Paul M.
openaire   +5 more sources

CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response

open access: yesFrontiers in Pharmacology, 2022
Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in ...
Nan Li   +11 more
doaj   +1 more source

Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome

open access: yesGut, 2021
Objective The microbiome directly affects the balance of pro-inflammatory and anti-inflammatory responses in the gut. As microbes thrive on dietary substrates, the question arises whether we can nourish an anti-inflammatory gut ecosystem.
L. Bolte   +12 more
semanticscholar   +1 more source

Anti-Inflammatory Action and Mechanisms of Resveratrol

open access: yesMolecules, 2021
Resveratrol (3,4′,5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body.
Tiantian Meng   +5 more
semanticscholar   +1 more source

Anti‐inflammatory hydrogel dressings and skin wound healing

open access: yesClinical and Translational Medicine, 2022
Hydrogels are promising and widely utilized in the biomedical field. In recent years, the anti‐inflammatory function of hydrogel dressings has been significantly improved, addressing many clinical challenges presented in ongoing endeavours to promote ...
Can Huang   +8 more
semanticscholar   +1 more source

CP-25 inhibits the hyperactivation of rheumatic synoviocytes by suppressing the switch in Gαs-Gαi coupling to the β2-adrenergic receptor

open access: yesCell Communication and Signaling, 2023
In essence, the β2 adrenergic receptor (β2AR) plays an antiproliferative role by increasing the intracellular cyclic 3’,5’-adenosine monophosphate (cAMP) concentration through Gαs coupling, but interestingly, β2AR antagonists are able to effectively ...
Mingli Ge   +11 more
doaj   +1 more source

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