Results 11 to 20 of about 5,289,236 (296)

Anti-Inflammatory Action and Mechanisms of Resveratrol

open access: yesMolecules, 2021
Resveratrol (3,4′,5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body.
Tiantian Meng   +5 more
semanticscholar   +1 more source

Mechanism of Antimicrobial Peptides: Antimicrobial, Anti-Inflammatory and Antibiofilm Activities

open access: yesInternational Journal of Molecular Sciences, 2021
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities. Exploring the mechanism of action of AMPs may help in the modification and
Ying Luo, Yuzhu Song
semanticscholar   +1 more source

GRK2 Mediates Macrophage Polarization by Regulating EP4-cAMP-pCREB Signaling in Ulcerative Colitis and the Therapeutic Effect of Paroxetine on Mice with DSS-Induced Colitis

open access: yesPharmaceuticals, 2023
G protein-coupled receptor kinase 2 (GRK2) is one of the cytosolic enzymes, and GRK2 translocation induces prostaglandin E2 receptor 4 (EP4) over-desensitization and reduces the level of cyclic adenosine monophosphate (cAMP) to regulate macrophage ...
Jiawei Zhang   +11 more
doaj   +1 more source

Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures

open access: yesDrug Design, Development and Therapy, 2021
Curcumin is a natural compound with great potential for disease treatment. A large number of studies have proved that curcumin has a variety of biological activities, among which anti-inflammatory effect is a significant feature of it.
Ying Peng   +7 more
semanticscholar   +1 more source

CP-25 ameliorates methotrexate induced nephrotoxicity via improving renal apoptosis and methotrexate excretion

open access: yesJournal of Pharmacological Sciences, 2021
Paeoniflorin-6′-O-benzene sulfonate (CP-25) is a derivative of Paeoniflorin. We investigate beneficial effect of CP-25 on methotrexate (MTX) induced nephrotoxicity in rats.
Xiao Wei   +8 more
doaj   +1 more source

MicroRNA-10b promotes arthritis development by disrupting CD4+ T cell subtypes

open access: yesMolecular Therapy: Nucleic Acids, 2022
Rheumatoid arthritis (RA) is an inflammation-involved disorder and features the disruption of CD4+ T lymphocytes. Herein, we describe that microRNA-10b-5p (miR-10b) promotes RA progression by disrupting the balance between subsets of CD4+ T cells.
Jiajie Tu   +9 more
doaj   +1 more source

Genistein: A Review on its Anti-Inflammatory Properties

open access: yesFrontiers in Pharmacology, 2022
Nowadays, non-resolving inflammation is becoming a major trigger in various diseases as it plays a significant role in the pathogenesis of atherosclerosis, asthma, cancer, obesity, inflammatory bowel disease, chronic obstructive pulmonary disease ...
Yu Xian Goh   +4 more
semanticscholar   +1 more source

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

open access: yesClinical Rheumatology, 2020
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes only mild symptoms in the majority of the cases, while immunologic complications such as macrophage activation syndrome also known as secondary hemophagocytic ...
M. Soy   +5 more
semanticscholar   +1 more source

Immune-Cell-Based Therapy for COVID-19: Current Status

open access: yesViruses, 2023
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. The interplay between innate and adaptive immune responses plays a crucial role in managing COVID-19.
Yiyuan Wang   +7 more
doaj   +1 more source

Bidirectional Role of β2-Adrenergic Receptor in Autoimmune Diseases

open access: yesFrontiers in Pharmacology, 2018
Disorder of the sympathetic nervous system (SNS) is closely related to the pathogenesis of various autoimmune diseases (ADs). Catecholamine triggered beta2-adrenergic receptor (β2-AR) signaling is important in creating a bidirectional response in the ...
Li Wu   +9 more
doaj   +1 more source

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