Results 61 to 70 of about 901,503 (311)
Pediatric DiscoveryAcute kidney injury (AKI) is a prevalent and serious clinical challenge with limited specific treatments. Phyllanthus urinaria L (PU), a well‐regarded herbal medicine, possesses noted anti‐inflammatory, antiviral, and antitumor properties.
Qitong Guo +8 more
doaj +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Diabetes mellitus is not only a chronic metabolic disorder but also an inflammatory one. Antidiabetic drugs are required to address both these entities to reduce the micro- and macro-complications associated with diabetes.
Rajashekar Y R +2 more
doaj +1 more source
Tetracycline Actions Relevant to Rosacea Treatment [PDF]
, 2009 Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity
Advances in Pharmacological and Pharmaceutical Sciences, 2022 The study involved extraction, identification, and evaluation of pharmacological activities of the phytochemicals present. Artocarpus hirsutus Lam, commonly known as Wild jack is a greatly valued medicinal plant, which belongs to the plant family ...
M. Karthik +5 more
doaj +1 more source
Investigation of the Chemical Composition and Efficiency of Seed Oil of Spindle Tree (Euonymus Europaea L.) on the Model of Non-allergic Dermatitis [PDF]
, 2018 The aim of the research was to study the chemical composition and effectiveness of the seed oil of Spindle tree (Euonymus europaea L.) on the non-allergic contact dermatitis model.The oil was obtained by the extraction by petroleum ether from the seeds ...
Vrubel, O. (Olha) +2 more
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
New insights into the anti-inflammatory mechanisms of glucocorticoids : an emerging role for glucocorticoid-receptor-mediated transactivation [PDF]
, 2013 Glucocorticoids are anti-inflammatory drugs that are widely used for the treatment of numerous (autoimmune) inflammatory diseases. They exert their actions by binding to the glucocorticoid receptor (GR), a member of the nuclear receptor family of ...
Dejager, Lien +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Selective COX-2 inhibitors and risk of myocardial infarction [PDF]
, 2005 Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids.
Klauss, V. +3 more
core +1 more source