Results 11 to 20 of about 7,359,914 (273)

Anti-Modified Protein Antibodies in Rheumatoid Arthritis: Pathogenic, Protective, or Passive Bystander? [PDF]

Immunol Rev
ABSTRACT The presence of anti‐modified protein antibodies (AMPA) is a hallmark of rheumatoid arthritis (RA). AMPA recognize post‐translationally modified proteins and are cross‐reactive. AMPA include anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies ...
Stalman AFL, van der Woude D.
europepmc   +3 more sources

Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response

RMD Open
Objective Gut-residing bacteria, such as Escherichia coli, can acetylate their proteome under conditions of amine starvation. It is postulated that the (gut) microbiome is involved in the breach of immune tolerance to modified self-proteins leading to ...
Tom W J Huizinga, Diane van der Woude, René E M Toes, Mikhail Volkov, Peter A van Veelen, Joanneke C Kwekkeboom, Karin A J van Schie, Arieke S B Kampstra, Anouk G van Mourik, Arnoud de Ru   +9 more
doaj   +4 more sources

Expression of recombinant multi-coloured fluorescent antibodies in gor ^-/trxB^- E. coli cytoplasm [PDF]

, 2011
Background Antibody-fluorophore conjugates are invaluable reagents used in contemporary molecular cell biology for imaging, cell sorting and tracking intracellular events.
Durvasula, Ravi V., Burchell, Joy Marilyn; id_orcid, Kang, Angray S., Anatoliy Markiv, Burchell, J, Durvasula, R.V., Beatson, R., Beatson Richard, Beatson, Richard; id_orcid, Kang Angray S, Markiv, A., Markiv Anatoliy, Kang, A.S., Richard Beatson, Burchell, J., Durvasula Ravi V, Ravi V Durvasula, Burchell, Joy; id_orcid, Durvasula, RV, Markiv, Anatoliy, Burchell Joy, Markiv, A, Angray S Kang, Beatson, Richard, Joy Burchell, Kang, AS, Beatson, R   +26 more
core   +1 more source

Ultrasensitive Determination of Glial-Fibrillary-Acidic-Protein (GFAP) in Human Serum-Matrix with a Label-Free Impedimetric Immunosensor

Biosensors, 2022
In this work, immobilizing anti-GFAP antibodies via covalent attachment onto L-cysteine/gold nanoparticles that were modified with screen-printed carbon electrodes (Anti-GFAP/L-cys/AuNps/SPCE) resulted in the development of a sensitive label-free ...
Goksu Ozcelikay, Fariba Mollarasouli, Mehmet Altay Unal, Kıvılcım Gucuyener, Sibel A. Ozkan   +4 more
doaj   +1 more source

Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice [PDF]

, 2010
The motor axonal variant of Guillain-Barré syndrome is associated with anti-GD1a immunoglobulin antibodies, which are believed to be the pathogenic factor. In previous studies we have demonstrated the motor terminal to be a vulnerable site.
Halstead, S., Furukawa, K., Humphreys, P.D, Willison, H.J., McGonigal, R., Rowan, E.G., Greenshields, K.N, Rother, R.P   +7 more
core   +2 more sources

Erytra blood group analyser and kode technology testing of SARS‐CoV‐2 antibodies among convalescent patients and vaccinated individuals

eJHaem, 2022
Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic requires tests to monitor antibody formation and prevalence. We detected SARS‐CoV‐2 antibodies using red cells coated by Kode technology with short peptides derived
Christof Weinstock, Willy A. Flegel, Kshitij Srivastava, Sabine Kaiser, Hubert Schrezenmeier, Chrysanthi Tsamadou, Carolin Ludwig, Bernd Jahrsdörfer, Nicolai V. Bovin, Stephen M. Henry   +9 more
doaj   +1 more source

Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules [PDF]

, 2011
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Schepens, B, Temperton, Nigel J., M. Koenders, C. Theo Verrips, Schillemans, J, Ibanez, Lorena Itatı, J. Melero, de Haard, HJ, Verrips, C. Theo, S. Van Gucht, C.T. Verrips, Michael Saunders, Bert Schepens, Temperton, Nigel J, Ibanez, Lorena, Koenders, M, Melero, Jose A., Schepens Bert, de Haard, Hans J, Vanlandschoot, P, Steven Van Gucht, Gonzalez-Pajuelo Maria, Van Gucht, S, Xavier Saelens, Vanlandschoot Peter, Anna Hultberg, B. Schepens, Gonzalez-Pajuelo, Maria, Schillemans Joris, Koenders, Mireille, Nigel J. Temperton, Saunders Michael, Melero José A., de Haard, Hans J., Schillemans, Joris, Ibañez Lorena Itatí, de Haard Hans J., Temperton Nigel J., Ibañez,, Lorena Itatí, H.J. de Haard, Robin A. Weiss, Hultberg, A, Schepens, Bert, C Theo Verrips, N.J. Temperton, Ibanez, LI, Van Gucht, Steven, Verrips, Theo, Maria Gonzalez-Pajuelo, L.I. Ibanez, Rosseels Valérie, José A Melero, Hans J de Haard, Mireille Koenders, Hultberg Anna, Weiss, RA, Saelens Xavier, Saunders, Michael, R.A. Weiss, Weiss Robin A., Saelens, Xavier, Hans J. de Haard, Lorena Itatí Ibañez, A. Hultberg, Gonzalez-Pajuelo, M, Weiss, Robin A., Saelens, X, Joris Schillemans, Verrips, CT, Peter Vanlandschoot, Van Gucht Steven, M. Saunders, Valérie Rosseels, V. Rosseels, Koenders Mireille, Robin A Weiss, P. Vanlandschoot, Rosseels, V, José A. Melero, Hultberg, Anna, M. Gonzalez-Pajuelo, Rosseels, Valerie, J. Schillemans, Ibañez, Lorena Itatí, Melero, Jose Antonio, Vanlandschoot, Peter, Weiss, Robin A, Saunders, M, Nigel J Temperton, X. Saelens, Melero, José A, Verrips C. Theo, Temperton, NJ, Melero, JA, Verrips, C Theo   +94 more
core   +1 more source

Exploiting Natural Cross-reactivity between Human Immunodeficiency Virus (HIV)-1 p17 Protein and Anti-gp41 2F5 Antibody to Induce HIV-1 Neutralizing Responses In Vivo

Frontiers in Immunology, 2017
Anti-p17 antibodies are able to neutralize human immunodeficiency virus (HIV) entry in a mouse model. In this study, we identified a region of sequence similarity between the epitopes of anti-p17 neutralizing antibodies and anti-gp41 neutralizing 2F5 ...
Bernard Verrier, Stéphane Paul, Céline Terrat, Liza Bastide, Agathe Ensinas, Agathe Ensinas, Capucine Phelip, Blandine Chanut, Laura Bulens-Grassigny, Laura Bulens-Grassigny, Fabienne Jospin, Christophe Guillon   +11 more
doaj   +1 more source

New insights into the microscopic interactions associated with the physical mechanism of action of highly diluted biologics

Scientific Reports, 2021
In this investigation, we report the effect on the microscopic dynamics and interactions of the cytokine interferon gamma (IFN-γ) and antibodies to IFN-γ (anti-IFN-γ) and to the interferon gamma receptor 1 (anti-IFNGR1) prepared in exceptionally dilute ...
Kristina N. Woods
doaj   +1 more source

Additional file 1 of Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load

, 2021
Additional file 1. Supplementary material and methods.
Reijm, Sanne, Kissel, Theresa, Stoeken-Rijsbergen, Gerrie, Slot, Linda M., Wortel, Corrie M., van Dooren, Hugo J., Levarht, Nivine E. W., Kampstra, Arieke S. B., Derksen, Veerle F. A. M., Heer, Pleuni Ooijevaar-de, Bang, Holger, Drijfhout, Jan W., Trouw, Leendert A., Huizinga, Tom W. J., Rispens, Theo, Scherer, Hans U., Toes, René E. M.   +16 more
openaire   +1 more source