Results 91 to 100 of about 1,938,563 (139)

Reduction in Xenogeneic Epitopes on Porcine Endothelial Cells by Periodate Oxidation

Biomedicines
Background: Patterns of humoral immune responses represent a major hurdle in terms of pig-to-human xenotransplantation approaches. The best-known xenogeneic glycan antigens present in pigs are the αGal (Galili antigen) and the non-human sialic acid ...
Jonas Thom, Nathalie Roters, Slavica Schuemann, Birgit Andrée, Falk F. R. Buettner, Andres Hilfiker, Tobias Goecke, Robert Ramm   +7 more
doaj   +1 more source

Characterization of anti-Neu5Gc IgA and IgG in Kawasaki disease patients’ sera. A.

, 2013
Details of the cohort of sera used for analysis of antibodies. Coronary arteries (CA) status represents normal (CA1) or damaged with aneurysm (CA2) or dilatation (CA3). B.
Hai Yu (366836), Jane C. Burns (268128), Vered Padler-Karavani (375363), Adriana H. Tremoulet (387274), Ajit Varki (375367), Xi Chen (35903)   +5 more
core   +1 more source

Affinity purified Chicken IgY antibody recognizes Neu5Gc with various linkages to underlying glycans.

, 2013
A. Detection of Neu5Gc on synthetic and semi-synthetic molecules. Reactivity of the affinity-purified anti-Neu5Gc antibody was tested in triplicate, by ELISA against synthetic and semi-synthetic Neu5Gc- and Neu5Ac-target pairs, using Neu5Ac-glycans for ...
Nancy Hurtado-Ziola (375365), Els C. M. Brinkman-Van der Linden (375366), Hai Yu (366836), Sandra L. Diaz (375362), Vered Padler-Karavani (375363), Nissi M. Varki (243827), Ajit Varki (375367), Darius Ghaderi (375364), Xi Chen (35903)   +8 more
core   +1 more source

Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response

, 2015
International audienceAnti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum Sickness Diseases (SSD).
Evanno, G., Le Berre, L., Castagnet, S., Bach, Jean-Marie, Jean-Paul, S., Couvrat-Desvergnes, G., Lorent, Marine, Veselý, P., Nicot, A., Harb, J., Brouard, S., Hruba, P., Giral, M., Guérif, P., Viklický, O., Salama, A., Foucher, Y.   +16 more
core   +2 more sources

Method establishment for discerned immunogenicity assessment of a recombinant glycoprotein containing nonhuman sialic acid Neu5Gc residues

, 2017
Aim: Recombinant glycoprotein produced in nonhuman mammalian cell lines can be modified with the immunogenic nonhuman sialic N-glycolylneuraminic acid (Neu5Gc).
Heinrich Faust, Marc-Olivier Montjovent, Linglong Zou, Petra Struwe, Afsaneh Abdolzade-Bavil, Patrick M Liu   +5 more
core   +1 more source

Characterization of immunogenic Neu5Gc in bioprosthetic heart valves

Background: The two common sialic acids (Sias) in mammals are N-acetylneuraminic acid (Neu5Ac) and its hydroxylated form N-glycolylneuraminic acid (Neu5Gc). Unlike most mammals, humans cannot synthesize Neu5Gc that is considered foreign and recognized by
Cozzi, Emanuele, Chen, Xi, Fellah-Hebia, Imen, Galinanes, Manuel, Moshe Reuven, Eliran, Marshanski, Tal, Máñez, Rafael, Costa Vallés, Cristina, Leviatan Ben-Arye, Shani, Yu, Hai, Roussel, Jean-Christian, Soulillou, Jean-Paul, Breimer, Michael E., Tourneau, Thierry Le, Padler-Karavani, Vered   +14 more
core  

Influence of anti-Neu5Gc and anti-alpha-1-3-Galactose antibodies in the immune response

, 2019
L’espèce humaine a perdu lors de l’évolution la capacité de synthétiser certains hydrates de carbone et voit sa glycosylation des protéines et des lipides modifiée par rapport aux autres mammifères.
Rousse, Juliette
core  

Qualitative Characterization of Neu5Gc-Containing N-Glycans in Commercial Cheddar Cheese Products Using Nano-UHPLC-ESI-MS/MS-A Pilot Study. [PDF]

Int J Mol Sci
Mogut D, Goli M, Reyes CDG, Mechref Y, Iwaniak A.   +4 more
europepmc   +1 more source

Monitoring of the sialylation and polysialylation status of sheep milk during early lactation. [PDF]

JDS Commun
Isernhagen L, Helffenstein K, Seidel A, Kuhla B, Galuska SP.   +4 more
europepmc   +1 more source

Analysis of the Milk Oligosaccharides Spectrum and Sialylation Status of Milk from West African Dwarf Goat and East Friesian Sheep. [PDF]

ACS Omega
Isernhagen L, Galuska CE, Hoeflich A, Galuska SP.   +3 more
europepmc   +1 more source