CHARACTERIZATION AND ANTIPARASITIC ACTIVITY OF BENZOPHENONE THIOSEMICARBAZONES ON Trypanosoma brucei brucei [PDF]
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2011 The structure of four synthesized thiosemicarbazones, substituted or not, of benzophenone has been confirmed by spectrometrical analysis IR, NMR 1H and 13C. Their anti-trypanosomal activities were evaluated on Trypanosoma brucei brucei.
Georges C. Accrombessi +5 more
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Anti-Trypanosomal Bufadienolides from the Oocytes of the Toad Rhinella alata (Anura, Bufonidae) [PDF]
Molecules, 2023 Amphibians are widely known as a prolific source of bioactive metabolites. In this work, we isolated and characterized compounds with antiparasitic activity from the oocytes of the toad Rhinella alata collected in Panama.
Candelario Rodriguez +6 more
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Anti-trypanosomal activity of 1,2,3,4,6-penta-O-galloyl-β -D-glucose isolated from Plectranthus barbatus Andrews (Lamiaceae) [PDF]
Química Nova, 2012 MeOH extract from the leaves of Plectranthus barbatus Andrews (Lamiaceae), showed in vitro anti-trypanosomal activity. The bioassay-guided fractionation resulted in the isolation of a gallic acid derivative, identified as 1,2,3,4,6-penta-O-galloyl-β-D ...
Roberta T. dos Santos +5 more
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Sokoto Journal of Veterinary SciencesThe use of plants in traditional medicine is increasingly gaining ground in modern medicine because phytochemical components of most secondary metabolites can be used to treat a wide range of diseases.
CS Ukwueze, MU Ememe, R Unigwe, CG Nwosu
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Bayero Journal of Pure and Applied Sciences, 2021 This study was carried out to screen for anti-trypanosomal activities of Sterculia setigera crude and nano-conjugated ethanol extracts of synthesized gold nanoparticles (AuNPs). Fresh stem bark of S.
M.O. Abdulrazaq +4 more
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, 2020 Aims: This study presents baseline data on the In-vitro and In-vivo evaluation of anti-trypanosomal activity of Carica papaya seed extracts and fractions in Albino Wister rats. Study Design: Mention the design of the study here.
H. Kinjir +2 more
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Discovery of Trypanosoma brucei inhibitors enabled by a unified synthesis of diverse sulfonyl fluorides [PDF]
Communications ChemistrySets of electrophilic probes are generally prepared using a narrow toolkit of robust reactions, which tends to limit both their structural and functional diversity.
Brian S. Mantilla +6 more
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Crosspteryx fibrifuga leaf extract enhances host resistance to Trypanosoma congolense infection in mice by regulating host immune response and disrupting the activity of parasite superoxide dismutase enzyme [PDF]
Frontiers in Microbiology, 2023 African trypanosomiasis, a neglected tropical disease, is caused by diverse species of the protozoan parasite belonging to the genus Trypanosoma. Although anti-trypanosomal medications exist, the increase in drug resistance and persistent antigenic ...
Nnamdi Ikeogu +7 more
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Steroid Alkaloids from Holarrhena africana with Strong Activity against Trypanosoma brucei rhodesiense [PDF]
Molecules, 2017 In our continued search for natural compounds with activity against Trypanosoma brucei, causative agent of human African trypanosomiasis (HAT, “sleeping sickness”), we have investigated extracts from the leaves and bark of the West African Holarrhena ...
Charles Okeke Nnadi +4 more
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