Results 31 to 40 of about 2,622 (160)
Plants, 2021 Marine halophytes are an outstanding reservoir of natural products and several species have anti-infectious traditional uses. However, reports about their potential use against neglected tropical ailments, such as Chagas disease, are scarce.
Catarina G. Pereira +9 more
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In vitro Anti-Trypanosomal Activities of Indanone-Based Chalcones [PDF]
Drug Research, 2018 Human African trypanosomiasis is a neglected infectious disease that affects mostly people living in the rural areas of Africa. Current treatment options are limited to just four drugs that have been in use of four to nine decades. The life-threatening toxic side-effects associated with the use of these drugs are disconcerting.
Beteck, Richard M +3 more
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Anti-trypanosomal activity of doubly modified salinomycin derivatives [PDF]
European Journal of Medicinal Chemistry, 2019 As a group of biologically active compounds, polyether antibiotics (ionophores) show a broad spectrum of interesting pharmacological properties, ranging from anti-bacterial to anti-cancer activities. There is increasing evidence that ionophores, including salinomycin (SAL), and their semi-synthetic analogues are promising candidates for the development
Michał Antoszczak +4 more
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The anti‐Trypanosoma activities of medicinal plants: A systematic review of the literature
Veterinary Medicine and Science, 2022 Background The existing drug treatments for trypanosomiases are limited and suffer from shortcomings due to their toxicity and the emergence of resistant parasites.
Shahin Nekoei +5 more
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Clinical Phytoscience, 2020 Objective The present study investigated the anti-Trypanosoma brucei brucei activity of methanolic extract of Senna occidentalis roots, leaves, stem bark, and seed in vitro and bioactive components of the most active plant part.
Zainab Aliyu Alhafiz +4 more
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ANTI‐TRYPANOSOMAL ACTIVITY OF CERTAIN PHENYLDIAZOAMINO‐ AND PHENYLAZOAMINO‐PHENANTHRIDINIUM COMPOUNDS [PDF]
British Journal of Pharmacology and Chemotherapy, 1961 Red phenyldiazoaminophenanthridinium and purple phenylazoaminophenanthridinium compounds, most of which were obtained as isomeric pairs, were tested in mice for curative and prophylactic action against Trypanosoma congolense. Several of the individual compounds showed a high degree of activity, the red isomer of each pair usually being more active ...
K N, BROWN, J, HILL, A E, HOLLAND
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Chemical characterization of Saudi propolis and its antiparasitic and anticancer properties
Scientific Reports, 2021 Propolis, is a gummy material produced by honey bees from different parts of plants and is enriched with varied biological active compounds like flavonoids, phenolics and phenolic acids with wide applicability in the food, pharmaceutical and cosmetics ...
Samyah Alanazi +4 more
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EUCALYPTUS OIL NANOEMULSION: EVALUATION OF IN VITRO ACTIVITY AGAINST TRYPANOSOMA BRUCEI [PDF]
Zagazig Journal of Pharmaceutical SciencesBackground: Natural products and their secondary metabolites are a good source of pharmacologically active constituents and have been widely developed into modern medicines.
Emmanuel Maduabuchi Uronnachi +4 more
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Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads. [PDF]
PLoS Neglected Tropical Diseases, 2011 Trypanosoma brucei, the causative agent of Human African Trypanosomiasis (HAT), expresses two proteins with homology to human glycogen synthase kinase 3β (HsGSK-3) designated TbruGSK-3 short and TbruGSK-3 long.
Richard O Oduor +9 more
doaj +1 more source
Correction: Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies
PLoS Neglected Tropical Diseases, 2012 The image for Figure 1 is incorrect.
Guy Caljon +6 more
openaire +4 more sources