Results 51 to 60 of about 7,391,676 (191)

Anti-trypanosomal activity of compounds on Trypanosoma brucei brucei.

open access: yes, 2019
Anti-trypanosomal activity of compounds on Trypanosoma brucei brucei.
Jonathan Partt Adjimani (6397199)   +3 more
core   +1 more source

Screening, identification, structure-activity, and mode of action studies with new antitrypanosomal leads of plant and fungal origin [PDF]

open access: yes, 2013
Human African trypanosomiasis (HAT) is a neglected disease caused by the protozoan Trypanosoma brucei, which is transmitted during blood-feeding tsetse fly bites.
Zimmermann, Stefanie
core   +1 more source

Antiplasmodial, anti-trypanosomal, anti-leishmanial and cytotoxicity activity of selected Tanzanian medicinal plants [PDF]

open access: yes, 2010
The antiplasmodial, anti-trypanosomal and anti-leishmanial activity of 25 plant extracts obtained from seven Tanzanian medicinal plants: Annickia (Enantia) kummeriae (Annonaceae), Artemisia annua (Asteraceae), Pseudospondias microcarpa (Anacardiaceae)
Tanja, W.   +9 more
core   +1 more source

Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues [PDF]

open access: yes, 2008
Glycosylphosphatidylinositol (GPI)-anchored proteins are abundant in the protozoan parasite Trypanosoma brucei, the causative agent of African sleeping sickness in humans and the related disease Nagana in cattle, and disruption of GPI biosynthesis is ...
Nikolaev, Andrei V.   +4 more
core   +5 more sources

Trypanosomal MICOS Is Assembled on Non‐Respiring Mitochondrial Crista Precursors and Associates With Two Integral Microproteins

open access: yesMolecular Microbiology, EarlyView.
The mitochondrial membrane‐shaping machinery MICOS is assembled surprisingly early during the life cycle of Trypanosoma brucei, before the mitochondrion acquires its mature architecture or full respiratory capacity. Our study also identifies two previously uncharacterized proteins associated with MICOS, providing new insight into the early organization
Michala Boudová   +5 more
wiley   +1 more source

In vitro anti-trypanosomal activity of Bitis arietans crude venom against Trypanosoma brucei brucei [PDF]

open access: yes, 2019
African Animal trypanosomosis (AAT) otherwise known as Nagana is a resurgent disease in Africa. It is caused by Trypanosoma brucei brucei, Trypanosoma congolense, Trypanosoma vivax, Trypanosoma evansi among others.
Peter, G, Chechet, G.D.
core   +1 more source

Potential Mechanism of the Anti-trypanosomal Activity of Organoruthenium Complexes with Bioactive Thiosemicarbazones

open access: yesBiological Trace Element Research, 2013
In the search for new metal-based drugs against diseases produced by trypanosomatid parasites, four organoruthenium(II) compounds [Ru2(p-cymene)2(L)2]X2, where L are bioactive 5-nitrofuryl-containing thiosemicarbazones and X = Cl or PF6, had been previously obtained.
Demoro, Bruno   +12 more
openaire   +2 more sources

In vitro trypanocidal evaluation of pinane derivatives from essential oils of ripe fruits from Schinus terebinthifolius Raddi (Anacardiaceae)

open access: yesQuímica Nova, 2012
Essential oils of ripe fruits from Schinus terebinthifolius (Anacardiaceae), obtained using a pilot extractor and a Clevenger apparatus were chemically characterized.
Patricia Sartorelli   +8 more
doaj   +1 more source

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm   +2 more
wiley   +1 more source

Anti-trypanosomal activity of 1,2,3,4,6-penta-O-galloyl-β -D-glucose isolated from Plectranthus barbatus Andrews (Lamiaceae)

open access: yesQuímica Nova, 2012
MeOH extract from the leaves of Plectranthus barbatus Andrews (Lamiaceae), showed in vitro anti-trypanosomal activity. The bioassay-guided fractionation resulted in the isolation of a gallic acid derivative, identified as 1,2,3,4,6-penta-O-galloyl-β-D ...
Roberta T. dos Santos   +5 more
doaj   +1 more source

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