Results 51 to 60 of about 2,259,235 (294)

Characterization of Defensin-like Protein 1 for Its Anti-Biofilm and Anti-Virulence Properties for the Development of Novel Antifungal Drug against Candida auris

open access: yesJournal of Fungi, 2022
Candida auris has emerged as a pan-resistant pathogenic yeast among immunocompromised patients worldwide. As this pathogen is involved in biofilm-associated infections with serious medical manifestations due to the collective expression of pathogenic ...
Majid Rasool Kamli   +3 more
doaj   +1 more source

Predicting the virulence of MRSA from its genome sequence [PDF]

open access: yes, 2014
This work is supported by the EC-FP7 program no. 245500 and the BBSRCMicrobial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen's evolutionary trajectory.
Josefsson, Elisabet,   +89 more
core   +1 more source

Toward Mycobacterium tuberculosis Virulence Inhibition: Beyond Cell Wall

open access: yesMicroorganisms
Mycobacterium tuberculosis (Mtb) is one of the most successful bacterial pathogens in human history. Even in the antibiotic era, Mtb is widespread and causes millions of new cases of tuberculosis each year.
Maria S. Kotliarova   +2 more
doaj   +1 more source

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus [PDF]

open access: yes, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H.   +7 more
core   +1 more source

Anti-Pathogenic Properties of the Combination of a T3SS Inhibitory Halogenated Pyrrolidone with C-30 Furanone

open access: yesMolecules, 2021
Antimicrobial resistance is one of the current public health challenges to be solved. The World Health Organization (WHO) has urgently called for the development of strategies to expand the increasingly limited antimicrobial arsenal.
Nelly Araceli Aburto-Rodríguez   +8 more
doaj   +1 more source

Molecular Targets in Streptococcus pyogenes for the Development of Anti-Virulence Agents. [PDF]

open access: yesGenes (Basel)
Streptococcus pyogenes, commonly known as Group A Streptococcus (GAS), is a significant human pathogen responsible for a wide range of diseases, from mild pharyngitis to severe conditions such as necrotizing fasciitis and toxic shock syndrome. The increasing antibiotic resistance, especially against macrolide antibiotics, poses a challenge to the ...
Cho KH.
europepmc   +3 more sources

Selection of virulence-associated determinants of Streptococcus suis serotype 2 by in vivo complementation [PDF]

open access: yes, 2001
Within Streptococcus suis serotype 2, pathogenic, weakly pathogenic, and nonpathogenic strains can be found. We introduced a genomic library of a pathogenic strain into a weakly pathogenic strain.
Smith, H.E.   +9 more
core   +1 more source

A Genome-Wide Association Study Identifies Genomic Regions for Virulence in the Non-Model Organism Heterobasidion annosum ss [PDF]

open access: yes, 2013
The dense single nucleotide polymorphisms (SNP) panels needed for genome wide association (GWA) studies have hitherto been expensive to establish and use on non-model organisms.
Olson, Åke   +5 more
core   +3 more sources

Steps toward broad-spectrum therapeutics : discovering virulence-associated genes present in diverse human pathogens [PDF]

open access: yes, 2009
© 2009 Stubben et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Karlyshev, Andrey V.   +37 more
core   +1 more source

Quorum Sensing Inhibition by Sponge-Associated Bacillus Species: Suppressing Pseudomonas aeruginosa Virulence Factors

open access: yesAntibiotics
Background/Objectives: The growing threat of antimicrobial resistance has intensified the search for alternative therapeutic approaches. Quorum sensing (QS) inhibition, which disrupts bacterial communication and virulence, represents a promising approach
Carrie Shelouise Jacobs   +2 more
doaj   +1 more source

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