Results 51 to 60 of about 69,808 (218)

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

Pediatric HIV Infection

Iranian Journal of Allergy, Asthma and Immunology, 2004
HIV infection by maternal transmission is increasing in the world due to the increase in infected women who are not receiving appropriate antiretroviral therapy.
Teresa Espanol, Isabel Caragol, Pere Soler, Manuel Hernez   +3 more
doaj  

Eventos adversos relacionados à profilaxia anti-retroviral em acidentes ocupacionais Adverse events relating to antiretroviral prophylaxis for occupational accidents

Revista de Saúde Pública, 2007
O objetivo do estudo foi descrever os eventos adversos clínicos e laboratoriais secundários ao uso dos agentes anti-retrovirais em indivíduos submetidos à quimioprofilaxia.
Eduardo Alexandrino Servolo Medeiros, Elcio Bakowski, Silvia Janice Gomes Sassi, Alessandra Santana Destra   +3 more
doaj   +1 more source

A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]

, 2009
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Risk of severe bacterial infections including TB before and after immediate or deferred antiretroviral therapy: A multicenter, prospective, cohort study

International Journal of Infectious Diseases
Objectives: Deferring antiretroviral therapy (ART) until a CD4 count below cells/mm3 or other clinical indication in people with HIV (PWH) carries an increased risk of severe bacterial infections and tuberculosis (TB).
Tomas O. Jensen, Shweta Sharma, Anchalee Avihingsanon, Joseph Lutaakome, Indira Brar, William Burman, Ploenchan Chetchotisakd, Nathalie de Castro, Juan-Francisco Galán-Herrera, Nagalingeswaran Kumarasamy, Roger Paredes, Rene Ridzon, Michael Sciaudone, Kanal Singh, Alison Uriel, Jens Lundgren, Cavan Reilly, Gail Matthews   +17 more
doaj   +1 more source

Compreensão da terapia anti-retroviral: uma aplicação de modelo de traço latente Patient's understanding of information on antiretroviral therapy: an application of the latent trait model

Cadernos de Saúde Pública, 2008
O objetivo do estudo foi desenvolver um escore para determinar o nível de compreensão de informações sobre terapia anti-retroviral (TARV) em pacientes no início do tratamento. Estudo transversal baseado em entrevistas com pacientes infectados pelo HIV em
Maria das Graças B. Ceccato, Francisco A. Acurcio, Cibele C. César, Palmira F. Bonolo, Mark D. C. Guimarães   +4 more
doaj   +1 more source

Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair [PDF]

, 2015
A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of ...
Olson, Eric N., van Rooij, Eva
core   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Factors associated with dyslipidemia in seropositive patients for human immunodeficiency virus. Fadevic study.

Revista Ciencias Biomédicas, 2012
Introduction: with the argument of life expectancy of the people affected by HIV/AIDS, new challenges of health emerged. The dyslipidemias, in special, are presentedas a complication of the infection by the virus and the antiretroviral treatment(ARV). In
Velaides-Morelo Alberto, De la Vega-Del Risco Fernando, Bello-Espinosa Ariel   +2 more
doaj