Results 171 to 180 of about 5,870,697 (401)

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

Days of Therapy Avoided: A Novel Method for Measuring the Impact of an Antimicrobial Stewardship Program to Stop Antibiotics [PDF]

, 2018
Siddhant Datta, Mary L. Staicu, Mary Lourdes Brundige, Youssef Soliman, Maryrose Laguio‐Vila   +4 more
openalex   +1 more source

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia [PDF]

, 2022
Jumpei Yoshimura, Kazuma Yamakawa, Yoshinori Ohta, Kensuke Nakamura, Hideki Hashimoto, Masahiro Kawada, Hiroki Takahashi, Takeshi Yamagiwa, Akira Kodate, Kyohei Miyamoto, Satoshi Fujimi, Takeshi Morimoto   +11 more
openalex   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Rational antibiotic therapy

Indian Journal of Health Sciences and Biomedical Research KLEU, 2015
N S Mahantshetti
doaj   +1 more source

Association Between Antibiotic Treatment and the Efficacy of Intravesical BCG Therapy in Patients With High-Risk Non-Muscle Invasive Bladder Cancer [PDF]

, 2021
Sahyun Pak, Sun‐Young Kim, Sung Han Kim, Jae Young Joung, Weon Seo Park, Jinsoo Chung, Kang Hyun Lee, Ho Kyung Seo   +7 more
openalex   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Optimising the duration of antibiotic therapy for ventilator-associated pneumonia

European Respiratory Review, 2007
Ventilator-associated pneumonia (VAP) has traditionally been treated with a 14–21-day course of antibiotics. However, prolonged antibiotic therapy is associated with the emergence of multidrug-resistant strains, as well as higher toxicity and costs. In a
J. Chastre, C. E. Luyt
doaj  

Antibiotics for the critically ill: more than just selecting appropriate initial therapy [PDF]

, 2013
Marin H. Kollef
openalex   +1 more source

Empiric antibiotics for sepsis [PDF]

, 2018
Buckman, Sara A, Mazuski, John E, Turnbull, Isaiah R   +2 more
core   +2 more sources