Results 11 to 20 of about 185,660 (297)
Combating Antibiotic Tolerance Through Activating Bacterial Metabolism [PDF]
Frontiers in Microbiology, 2020 The emergence of antibiotic tolerance enables genetically susceptible bacteria to withstand the killing by clinically relevant antibiotics. As is reported, an increasing body of evidence sheds light on the critical and underappreciated role of antibiotic
Yuan Liu +9 more
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Antibiotics: Combatting Tolerance To Stop Resistance
mBio, 2019 Antibiotic resistance poses an alarming and ever-increasing threat to modern health care. Although the current antibiotic crisis is widely acknowledged, actions taken so far have proved insufficient to slow down the rampant spread of resistant pathogens.
Etthel M. Windels +4 more
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Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance
eLife, 2020 Predicting antibiotic efficacy within microbial communities remains highly challenging. Interspecies interactions can impact antibiotic activity through many mechanisms, including alterations to bacterial physiology.
Andrés Aranda-Díaz +7 more
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Antibiotic Tolerance and Combination Therapy
mBio, 2015 The recent paper by Haaber et al. (1) highlights another mechanism by which bacterial pathogens may evade the effects of antibiotics. The combination of colistin with vancomycin against Staphylococcus aureus may be antagonistic and may lessen the effectiveness of glycopeptide antibiotic. Colistin, it seems, induces gene expression in S.
David C. Bean, Sarah M. Wigmore
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Antibiotic tolerance in pneumococci [PDF]
Clinical Microbiology and Infection, 2002 When bacteria such as Staphylococcus aureus and Streptococcus pneumoniae are exposed to lytic antibiotics such as penicillin and vancomycin, a self-induced killing process is initiated in the organism. This killing occurs via both non-lytic and lytic processes.
Normark, Benriques Henriques +1 more
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Antibiotics, 2022 Pseudomonas aeruginosa infection is considered a high-risk nosocomial infection and is very difficult to eradicate because of its tolerance to antibiotic treatment.
Muhammad Reza Pahlevi +4 more
doaj +1 more source
mBio, 2021 Antibiotic resistance and tolerance pose a severe threat to human health. How bacterial pathogens acquire antibiotic tolerance is not clear.
Zhihui Lyu +4 more
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Non-responder phenotype reveals apparent microbiome-wide antibiotic tolerance in the murine gut
Communications Biology, 2021 Diener, Hoge et al. show that a third of mice exhibit tolerance to a high dose of the β-lactam antibiotic cefoperazone, independent of antibiotic treatment duration or dietary phytochemical amendment.
Christian Diener +7 more
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Mechanisms of Antibiotic Tolerance in Mycobacterium avium Complex: Lessons From Related Mycobacteria
Frontiers in Microbiology, 2020 Mycobacterium avium complex (MAC) species are the most commonly isolated nontuberculous mycobacteria to cause pulmonary infections worldwide. The lengthy and complicated therapy required to cure lung disease due to MAC is at least in part due to the ...
Harley Parker +4 more
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