Results 31 to 40 of about 1,969,887 (183)
Nucleic Acids Research, 2023 Pseudomonas aeruginosa harbors sophisticated transcription factor (TF) networks to coordinately regulate cellular metabolic states for rapidly adapting to changing environments.
Yujue Wang +8 more
semanticscholar +1 more source
Antibiotics, 2022 Bacteria can adapt to a changing environment by adopting alternate metabolic states favoring small molecule synthesis and resilience over growth. In Staphylococcus aureus, these states are induced by factors present during infection, including nutritional limitations, host responses and competition with other bacteria.
Emily M. Meredith +2 more
openaire +3 more sources
Microbiology spectrum, 2023 Bacterial antibiotic tolerance, a phenomenon first observed in 1944, is known to be responsible for both onset and exacerbation of recurrent and chronic bacterial infections.
Yingkun Wan +2 more
semanticscholar +1 more source
Non-responder phenotype reveals apparent microbiome-wide antibiotic tolerance in the murine gut
Communications Biology, 2021 Diener, Hoge et al. show that a third of mice exhibit tolerance to a high dose of the β-lactam antibiotic cefoperazone, independent of antibiotic treatment duration or dietary phytochemical amendment.
Christian Diener +7 more
doaj +1 more source
Community interactions drive the evolution of antibiotic tolerance in bacteria
bioRxiv, 2022 The emergence of antibiotic tolerance (prolonged survival against exposure) in natural bacterial populations is a major concern. Since it has been studied primarily in isogenic populations, we do not yet understand how ecological interactions in a ...
S. Mizrahi, Akshit Goyal, J. Gore
semanticscholar +1 more source
bioRxiv, 2022 As an important free energy source, the membrane voltage (Vm) regulates many essential physiological processes in bacteria. However, in comparison with eukaryotic cells, knowledge of bacterial electrophysiology is very limited.
Xin Jin +9 more
semanticscholar +1 more source
bioRxiv, 2022 Mycobacterium tuberculosis causes 10 million cases of active TB disease and over 1 million deaths worldwide each year. TB treatment is complex, requiring at least 6 months of therapy with a combination of antibiotics.
Alisha M. Block +6 more
semanticscholar +1 more source
Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance [PDF]
Antibiotics, 2020 Multidrug resistant bacteria are a global threat for human and animal health. However, they are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to their capacity to withstand antimicrobials is the formation of biofilms. Biofilms are associations of microorganisms embedded a self-produced extracellular matrix.
Cristina Uruén +4 more
openaire +7 more sources
Targeting Antibiotic Tolerance, Pathogen by Pathogen [PDF]
Cell, 2018 Antibiotic tolerance, the capacity of genetically susceptible bacteria to survive the lethal effects of antibiotic treatment, plays a critical and underappreciated role in the disease burden of bacterial infections. Here, we take a pathogen-by-pathogen approach to illustrate the clinical significance of antibiotic tolerance and discuss how the ...
Meylan, Sylvain +2 more
openaire +5 more sources
Antibiotics, 2020 Copper-derived compounds are often used in olive tree farms. In a previous study, a collection of bacterial strains isolated from olive tree farms were identified and tested for phenotypic antimicrobial resistance and heavy metal tolerance.
Nicolás Glibota +3 more
doaj +1 more source