Results 31 to 40 of about 188,321 (291)

Antimicrobial Peptides Can Generate Tolerance by Lag and Interfere with Antimicrobial Therapy

open access: yesPharmaceutics, 2022
Antimicrobial peptides (AMPs) are widely distributed molecules secreted mostly by cells of the innate immune system to prevent bacterial proliferation at the site of infection.
Daniel Sandín   +4 more
doaj   +1 more source

Tolerance and safety of the potentially probiotic strain Lactobacillus rhamnosus PRSF-L477 : a randomised, double-blind placebo-controlled trial in healthy volunteers [PDF]

open access: yes, 2010
In Europe, the species Lactobacillus rhamnosus is currently on the Qualified Presumption of Safety list used by the European Food Safety Authority (EFSA) for internal safety assessment, but according to the EFSA the species should remain a topic of ...
Huys, Geert   +4 more
core   +3 more sources

Adenosine Awakens Metabolism to Enhance Growth-Independent Killing of Tolerant and Persister Bacteria across Multiple Classes of Antibiotics

open access: yesmBio, 2022
Metabolic and growth arrest are primary drivers of antibiotic tolerance and persistence in clinically diverse bacterial pathogens. We recently showed that adenosine (ADO) suppresses bacterial growth under nutrient-limiting conditions.
David A. Kitzenberg   +7 more
doaj   +1 more source

Altered Antibiotic Tolerance in Anaerobic Digesters Acclimated to Triclosan Or Triclocarban [PDF]

open access: yes, 2016
Bench-scale anaerobic digesters were amended to elevated steady-state concentrations of triclosan (850 mg/kg) and triclocarban (150 mg/kg) using a synthetic feed.
Carey, Daniel Elliott   +1 more
core   +2 more sources

Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance [PDF]

open access: yesAntibiotics, 2020
Multidrug resistant bacteria are a global threat for human and animal health. However, they are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to their capacity to withstand antimicrobials is the formation of biofilms. Biofilms are associations of microorganisms embedded a self-produced extracellular matrix.
Cristina Uruén   +4 more
openaire   +7 more sources

Membrane Transporters of the Major Facilitator Superfamily Are Essential for Long-Term Maintenance of Phenotypic Tolerance to Multiple Antibiotics in E. coli

open access: yesMicrobiology Spectrum, 2021
Antibiotic tolerance is not only the key underlying the cause of recurrent and chronic bacterial infections but it is also a factor linked to exacerbation of diseases, such as tuberculosis, cystic fibrosis-associated lung infection, and candidiasis. This
Yingkun Wan   +3 more
doaj   +1 more source

Quaternary ammonium disinfectants and antiseptics: tolerance, resistance and potential impact on antibiotic resistance

open access: yesAntimicrobial Resistance and Infection Control, 2023
Background Due to the substantial increase in the use of disinfectants containing quaternary ammonion compounds (QACs) in healthcare and community settings during the COVID-19 pandemic, there is increased concern that heavy use might cause bacteria to ...
John M. Boyce
doaj   +1 more source

Pseudomonas aeruginosa Citrate Synthase GltA Influences Antibiotic Tolerance and the Type III Secretion System through the Stringent Response

open access: yesMicrobiology Spectrum, 2023
Carbohydrate metabolism plays essential roles in energy generation and providing carbon skeletons for amino acid syntheses. In addition, carbohydrate metabolism has been shown to influence bacterial susceptibility to antibiotics and virulence.
Hao Chen   +8 more
doaj   +1 more source

Piacentinu Ennese PDO cheese as reservoir of promising probiotic bacteria [PDF]

open access: yes, 2019
Piacentinu Ennese is a protected designation of origin (PDO) cheese produced in the surrounding area of Enna (Sicily, Italy), using raw ewe’s milk without the addition of any starter cultures.
Caggia, Cinzia   +6 more
core   +2 more sources

Antibiotic tolerance and persistence have distinct fitness trade-offs.

open access: yesPLoS Pathogens, 2022
Genetically susceptible bacteria can escape the action of bactericidal antibiotics through antibiotic tolerance or persistence. However, one major difference between the two phenomena is their distinct penetrance within an isogenic population. While with
Charlotte Michaux   +3 more
doaj   +1 more source

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