Results 21 to 30 of about 188,321 (291)

Antimicrobial Efficacy against Antibiotic-Tolerant Staphylococcus aureus Depends on the Mechanism of Antibiotic Tolerance

open access: yesAntibiotics, 2022
Bacteria can adapt to a changing environment by adopting alternate metabolic states favoring small molecule synthesis and resilience over growth. In Staphylococcus aureus, these states are induced by factors present during infection, including nutritional limitations, host responses and competition with other bacteria.
Emily M. Meredith   +2 more
openaire   +3 more sources

Non-responder phenotype reveals apparent microbiome-wide antibiotic tolerance in the murine gut

open access: yesCommunications Biology, 2021
Diener, Hoge et al. show that a third of mice exhibit tolerance to a high dose of the β-lactam antibiotic cefoperazone, independent of antibiotic treatment duration or dietary phytochemical amendment.
Christian Diener   +7 more
doaj   +1 more source

Heterogeneous Flagellar Expression in Single Salmonella Cells Promotes Diversity in Antibiotic Tolerance

open access: yesmBio, 2021
Antibiotic resistance and tolerance pose a severe threat to human health. How bacterial pathogens acquire antibiotic tolerance is not clear.
Zhihui Lyu   +4 more
doaj   +1 more source

The role of individual exopolysaccharides in antibiotic tolerance of Pseudomonas aeruginosa aggregates

open access: yesFrontiers in Microbiology, 2023
The bacterium Pseudomonas aeruginosa is involved in chronic infections of cystic fibrosis lungs and chronic wounds. In these infections the bacteria are present as aggregates suspended in host secretions.
Ziwei Liang   +8 more
doaj   +1 more source

Effects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs [PDF]

open access: yes, 2019
Strategies to reduce economic losses associated with post-weaning diarrhea in pig farming include high-level dietary zinc oxide supplementation.
Bethe, Astrid   +10 more
core   +2 more sources

Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms. [PDF]

open access: yes, 2020
Staphylococcus aureus biofilms are a significant problem in health care settings, partly due to the presence of a nondividing, antibiotic-tolerant subpopulation. Here we evaluated treatment of S.
Allan, RN   +7 more
core   +2 more sources

Targeting Antibiotic Tolerance, Pathogen by Pathogen [PDF]

open access: yesCell, 2018
Antibiotic tolerance, the capacity of genetically susceptible bacteria to survive the lethal effects of antibiotic treatment, plays a critical and underappreciated role in the disease burden of bacterial infections. Here, we take a pathogen-by-pathogen approach to illustrate the clinical significance of antibiotic tolerance and discuss how the ...
Meylan, Sylvain   +2 more
openaire   +5 more sources

Genetic Determinants for Metal Tolerance and Antimicrobial Resistance Detected in Bacteria Isolated from Soils of Olive Tree Farms

open access: yesAntibiotics, 2020
Copper-derived compounds are often used in olive tree farms. In a previous study, a collection of bacterial strains isolated from olive tree farms were identified and tested for phenotypic antimicrobial resistance and heavy metal tolerance.
Nicolás Glibota   +3 more
doaj   +1 more source

Fitness landscape of antibiotic tolerance in Pseudomonas aeruginosa biofilms. [PDF]

open access: yesPLoS Pathogens, 2011
Bacteria in biofilms have higher antibiotic tolerance than their planktonic counterparts. A major outstanding question is the degree to which the biofilm-specific cellular state and its constituent genetic determinants contribute to this hyper-tolerant ...
Sasan Amini   +3 more
doaj   +1 more source

Concentration-dependent activity of antibiotics in natural environments

open access: yesFrontiers in Microbiology, 2013
Bacterial responses to antibiotics are concentration dependent. At high concentrations, antibiotics exhibit antimicrobial activities on susceptible cells, while subinhibitory concentrations induce diverse biological responses in bacteria. At non-lethal
Steve P Bernier, Michael G Surette
doaj   +1 more source

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