Results 61 to 70 of about 1,969,887 (183)
S. pneumoniae is considered a serious threat by the Centers for Disease Control and Prevention because of rising antibiotic resistance. In addition to resistance, bacteria can also survive lethal antibiotic treatment by developing antibiotic tolerance ...
Nele Geerts +5 more
semanticscholar +1 more source
Glyphosate affects persistence and tolerance but not antibiotic resistance
Abstract Glyphosate is a herbicide widely used in food production that blocks the synthesis of aromatic amino acids in plants and in microorganisms and also induces the accumulation of the alarmone (p)ppGpp. Resistance, tolerance and persistence to antibiotics are common phenomena that contribute to antibiotic treatment failure.
Katia Ospino, Beny Spira
openaire +3 more sources
Antibiotic tolerance, or the ability of bacteria to survive antibiotic treatment in the absence of genetic resistance, often involves a low metabolic state. Here, Zheng et al. show that tolerance does not readily evolve against antibiotics whose efficacy
Erica J. Zheng +6 more
doaj +1 more source
Bugs on Drugs: A Drosophila melanogaster Gut Model to Study In Vivo Antibiotic Tolerance of E. coli
With an antibiotic crisis upon us, we need to boost antibiotic development and improve antibiotics’ efficacy. Crucial is knowing how to efficiently kill bacteria, especially in more complex in vivo conditions.
B. Van den Bergh
semanticscholar +1 more source
A Dietary Source of High Level of Fluoroquinolone Tolerance in mcr-Carrying Gram-Negative Bacteria
The emergence of antibiotic tolerance, characterized by the prolonged survival of bacteria following antibiotic exposure, in natural bacterial populations, especially in pathogens carrying antibiotic resistance genes, has been an increasing threat to ...
Tianqi Xu +4 more
doaj +1 more source
Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus
Staphylococcus aureus is a leading human pathogen that frequently causes relapsing infections. Host-pathogen interactions have been shown to have substantial impacts on antibiotic susceptibility and the formation of antibiotic tolerant cells.
Jenna E. Beam +4 more
semanticscholar +1 more source
Tolerability of moxifloxacin in patients with antibiotic hypersensitivity
Allergic reactions to antibiotics are commonly reported in the clinical practice. The treatment of antibiotic hypersensitivity (AH) consists of suggesting to avoid the offending antibiotics and to use safe alternatives after performing oral provocation tests (OPT). Moxifloxacin is a new fluoroquinolone antibacterial agent with a broad spectrum activity.
B, Bozkurt, G, Karakaya, A F, Kalyoncu
openaire +2 more sources
Collective antibiotic tolerance: mechanisms, dynamics and intervention [PDF]
Bacteria have developed resistance against every antibiotic at a rate that is alarming considering the timescale at which new antibiotics are developed. Thus, there is a critical need to use antibiotics more effectively, extend the shelf life of existing antibiotics and minimize their side effects.
Hannah R, Meredith +4 more
openaire +2 more sources
Staphylococcus aureus is a leading human pathogen that frequently causes chronic and relapsing infections. Antibiotic-tolerant persister cells contribute to frequent antibiotic failure in patients.
Jenna E. Beam +6 more
semanticscholar +1 more source
Adaptation and Antibiotic Tolerance of Anaerobic Burkholderia pseudomallei [PDF]
ABSTRACT The Gram-negative bacterium Burkholderia pseudomallei is the etiological agent of melioidosis and is remarkably resistant to most classes of antibacterials. Even after months of treatment with antibacterials that are relatively effective in vitro
Mohamad A, Hamad +5 more
openaire +2 more sources

