Results 61 to 70 of about 1,969,887 (183)

Antibiotic Tolerance Indicative of Persistence Is Pervasive among Clinical Streptococcus pneumoniae Isolates and Shows Strong Condition Dependence

open access: yesMicrobiology spectrum, 2022
S. pneumoniae is considered a serious threat by the Centers for Disease Control and Prevention because of rising antibiotic resistance. In addition to resistance, bacteria can also survive lethal antibiotic treatment by developing antibiotic tolerance ...
Nele Geerts   +5 more
semanticscholar   +1 more source

Glyphosate affects persistence and tolerance but not antibiotic resistance

open access: yesBMC Microbiology, 2022
Abstract Glyphosate is a herbicide widely used in food production that blocks the synthesis of aromatic amino acids in plants and in microorganisms and also induces the accumulation of the alarmone (p)ppGpp. Resistance, tolerance and persistence to antibiotics are common phenomena that contribute to antibiotic treatment failure.
Katia Ospino, Beny Spira
openaire   +3 more sources

Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies

open access: yesNature Communications, 2022
Antibiotic tolerance, or the ability of bacteria to survive antibiotic treatment in the absence of genetic resistance, often involves a low metabolic state. Here, Zheng et al. show that tolerance does not readily evolve against antibiotics whose efficacy
Erica J. Zheng   +6 more
doaj   +1 more source

Bugs on Drugs: A Drosophila melanogaster Gut Model to Study In Vivo Antibiotic Tolerance of E. coli

open access: yesMicroorganisms, 2022
With an antibiotic crisis upon us, we need to boost antibiotic development and improve antibiotics’ efficacy. Crucial is knowing how to efficiently kill bacteria, especially in more complex in vivo conditions.
B. Van den Bergh
semanticscholar   +1 more source

A Dietary Source of High Level of Fluoroquinolone Tolerance in mcr-Carrying Gram-Negative Bacteria

open access: yesResearch, 2023
The emergence of antibiotic tolerance, characterized by the prolonged survival of bacteria following antibiotic exposure, in natural bacterial populations, especially in pathogens carrying antibiotic resistance genes, has been an increasing threat to ...
Tianqi Xu   +4 more
doaj   +1 more source

Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

open access: yesbioRxiv, 2022
Staphylococcus aureus is a leading human pathogen that frequently causes relapsing infections. Host-pathogen interactions have been shown to have substantial impacts on antibiotic susceptibility and the formation of antibiotic tolerant cells.
Jenna E. Beam   +4 more
semanticscholar   +1 more source

Tolerability of moxifloxacin in patients with antibiotic hypersensitivity

open access: yesAllergologia et Immunopathologia, 2005
Allergic reactions to antibiotics are commonly reported in the clinical practice. The treatment of antibiotic hypersensitivity (AH) consists of suggesting to avoid the offending antibiotics and to use safe alternatives after performing oral provocation tests (OPT). Moxifloxacin is a new fluoroquinolone antibacterial agent with a broad spectrum activity.
B, Bozkurt, G, Karakaya, A F, Kalyoncu
openaire   +2 more sources

Collective antibiotic tolerance: mechanisms, dynamics and intervention [PDF]

open access: yesNature Chemical Biology, 2015
Bacteria have developed resistance against every antibiotic at a rate that is alarming considering the timescale at which new antibiotics are developed. Thus, there is a critical need to use antibiotics more effectively, extend the shelf life of existing antibiotics and minimize their side effects.
Hannah R, Meredith   +4 more
openaire   +2 more sources

Macrophage-Produced Peroxynitrite Induces Antibiotic Tolerance and Supersedes Intrinsic Mechanisms of Persister Formation

open access: yesbioRxiv, 2021
Staphylococcus aureus is a leading human pathogen that frequently causes chronic and relapsing infections. Antibiotic-tolerant persister cells contribute to frequent antibiotic failure in patients.
Jenna E. Beam   +6 more
semanticscholar   +1 more source

Adaptation and Antibiotic Tolerance of Anaerobic Burkholderia pseudomallei [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2011
ABSTRACT The Gram-negative bacterium Burkholderia pseudomallei is the etiological agent of melioidosis and is remarkably resistant to most classes of antibacterials. Even after months of treatment with antibacterials that are relatively effective in vitro
Mohamad A, Hamad   +5 more
openaire   +2 more sources

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