Results 1 to 10 of about 868,436 (327)
Antineoplastics Encapsulated in Nanostructured Lipid Carriers
Molecules, 2021 Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays, with well-defined therapeutic protocols.
Gustavo Henrique Rodrigues da Silva +6 more
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A case-control study of Clostridioides difficile symptomatic infections in a pediatric cancer hospital [PDF]
Revista Paulista de Pediatria, 2023 Objective: The aim of this study was to analyze and identify documented infections and possible risk factors for Clostridioides difficile infections in children with cancer. Methods: This is a retrospective case-control study, carried out in a pediatric
Adriana Maria Paixão de Sousa da Silva +10 more
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Isolation, Biosynthesis, and Biological Activity of Polycyclic Xanthones From Actinomycetes
Frontiers in Microbiology, 2022 Natural products from actinomycetes serve as a crucial source of clinical pharmaceuticals, especially antibiotics and anticancer agents. Among them, polycyclic xanthones belong to a growing group of highly oxygenated aromatic polyketides with a xanthone ...
Hui-Qing Yu +3 more
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Influence of fullerenol C60(OH)24 on enzime status in serum of rats after single dose administration of doxorubicine [PDF]
Hemijska Industrija, 2008 The antracycline antibiotics have one of the widest areas of use in oncology. The most investigated mechanisms of their antineoplastic activity include: interactions of these antibiotics with DNA, inhibition of topoisomerase II and production of free ...
Govedarica Biljana Č. +4 more
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Biological screening of a unique drug library targeting MRGPRX2
Frontiers in Immunology, 2022 BackgroundAllergic drug reaction or drug allergy is an immunologically mediated drug hypersensitivity reaction (DHR). G-protein coupled receptors (GPCRs) are common drug targets and communicate extracellular signals that initiate cellular responses ...
Fan Yang +8 more
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Ceftazidime and cefepime antagonize 5-fluorouracil’s effect in colon cancer cells
BMC Cancer, 2022 Background Drug-drug interaction (DDI), which can occur at the pharmacokinetics and/or the pharmacodynamics (PD) levels, can increase or decrease the therapeutic or adverse response of a drug itself or a combination of drugs.
Christina Pfab +6 more
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Antibiotics, 2021 Bloodstream infections (BSI) are a severe complication of antineoplastic chemotherapy or hematopoietic stem cell transplantation (HSCT), especially in the presence of antibiotic resistance (AR).
Elio Castagnola +23 more
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Frontiers in Pharmacology, 2023 Drug-induced acute kidney injury (DI-AKI) is one of the leading causes of kidney injury, is associated with high mortality and morbidity, and limits the clinical use of certain therapeutic or diagnostic agents, such as antineoplastic drugs, antibiotics ...
Jun Li +4 more
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Desensitization for the prevention of drug hypersensitivity reactions [PDF]
The Korean Journal of Internal Medicine, 2022 Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang +2 more
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Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds
Antibiotics, 2022 Microorganisms are known as important sources of natural compounds that have been studied and applied for different purposes in distinct areas. Specifically, in the pharmaceutical area, fungi have been explored mainly as sources of antibiotics, antiviral,
Rafael Conrado +3 more
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