Results 1 to 10 of about 855,663 (181)

Interactions of beta-lactam antibiotics and antineoplastic agents [PDF]

Antimicrobial Agents and Chemotherapy, 1983
The in vitro interactions of four beta-lactam antibiotics and five antineoplastic agents were examined with 100 clinically isolated strains of four species of gram-negative bacilli. Generally, by the checkerboard dilution method, beta-lactam antibiotics, when tested in combination with mitomycin C, bleomycin, or 5-fluorouracil, showed synergistic ...
Saikawa Isamu, Taki Hideo, Yoshikazu Fukuoka, A Saito, Yasushi Ikeda, T Yasuda, Yoshiko Yamashiro, Y Ueda   +7 more
openaire   +4 more sources

Efficacy of antineoplastic treatment is associated with the use of antibiotics that modulate intestinal microbiota [PDF]

OncoImmunology, 2016
Reduced anticancer efficacy of cyclophosphamide and platinum salts has been reported in animals treated with anti-Gram-positive antibiotics. These effects were related to translocation of Gram-positive bacteria during mucositis with subsequent induction of cytotoxic oxygen reactive species and tumor invasion by pathogenic Th17 cells.
Pflug, Natali, Kluth, Sandra, Vehreschild, Joerg J., Bahlo, Jasmin, Tacke, Daniela, Biehl, Lena, Eichhorst, Barbara, Fischer, Kirsten, Cramer, Paula, Fink, Anna-Maria, von Bergwelt-Baildon, Michael, Stilgenbauer, Stephan, Hallek, Michael, Cornely, Oliver A., Vehreschild, Maria J. G. T.   +14 more
openaire   +4 more sources

Adaptation of Bacteria to Antineoplastic Agents Involves Persister Cells and Increases Resistance to Antibiotics

Bioengineering, 2022
The increasing number of life-threatening infections observed in cancer patients has been ascribed to chemotherapy-induced neutropenia and to invasive medical procedures such as surgery and the application of catheters.
Carla C. C. R. de Carvalho
doaj   +3 more sources

Acute Generalized Exanthematous Pustulosis in a 76-year-Old Man With Neuroendocrine Carcinoma of the Lung, Responsive to Ixekizumab [PDF]

Clinical, Cosmetic and Investigational Dermatology
Jing Zhang,* Yue Chen,* Duanni Xu, Shaoyin Ma, Yichuan Gan, Yuwu Luo Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yue Chen; Yuwu Luo, Guangzhou ...
Zhang J, Chen Y, Xu D, Ma S, Gan Y, Luo Y   +5 more
doaj   +2 more sources

Novel Polymyxin Combination With Antineoplastic Mitotane Improved the Bacterial Killing Against Polymyxin-Resistant Multidrug-Resistant Gram-Negative Pathogens

Frontiers in Microbiology, 2018
Due to limited new antibiotics, polymyxins are increasingly used to treat multidrug-resistant (MDR) Gram-negative bacteria, in particular carbapenem-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.
Thien B. Tran, Thien B. Tran, Jiping Wang, Jiping Wang, Yohei Doi, Tony Velkov, Tony Velkov, Phillip J. Bergen, Phillip J. Bergen, Jian Li   +9 more
doaj   +2 more sources

Clinical characteristics and risk factors analysis of 505 cases of infusion reactions in a tertiary hospital [PDF]

Frontiers in Pharmacology
Background: The clinical characteristics and risk factors of infusion reactions (IRs) are inadequately described in clinical practice due to underreported cases.
Weiwei Yin, Bingqin Wen, Guoan Wang, Zhipeng Wang, Xuetao Kong, Yaozhou Wu, Xiao Meng, Xinyi Ou, Li Wei, Pengjiu Yu   +9 more
doaj   +2 more sources

Application of Optical Methods for Determination of Concentration of Doxorubicin in Blood and Plasma

Pharmaceuticals, 2022
The aim of presented research is to develop a simple and quick method of spectrophotometric detection for the determination of doxorubicin hydrochloride in blood and plasma.
Tomasz Sikora, Karolina Morawska, Wiesław Lisowski, Paweł Rytel, Agnieszka Dylong   +4 more
doaj   +1 more source

Effects of Concomitant Antibiotics Use on Immune Checkpoint Inhibitor Efficacy in Cancer Patients

Frontiers in Oncology, 2022
Objective Immune checkpoint inhibitors (ICIs) have changed the outcomes of a variety of cancers in an unprecedented manner. Gut microbiome plays a crucial regulatory role in the antineoplastic therapy of ICIs, which can be influenced by antibiotic (ABX ...
Shuai Jiang, Shuai Geng, Qiang Chen, Chen Zhang, Mengfei Cheng, Yang Yu, Shuo Zhang, N. Shi, Mei Dong   +8 more
semanticscholar   +1 more source

Analysis of 12 cases of antineoplastic agents-induced interstitial lung disease

Frontiers in Pharmacology, 2023
Objective: To summarize the situation of antineoplastic agents-induced interstitial lung diseases (ILD), provide reference for strengthening clinical management of druginduced interstitial lung diseases (DILD).Methods: We retrospectively investigated the
Xiao Li, Yong-Li Gu, Xu-Chao Liu, Zeng-Xian Sun, Ying Sun   +4 more
doaj   +1 more source

Antineoplastics Encapsulated in Nanostructured Lipid Carriers

Molecules, 2021
Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays, with well-defined therapeutic protocols.
Gustavo Henrique Rodrigues da Silva, Ludmilla David de Moura, Fabíola Vieira de Carvalho, Gabriela Geronimo, Talita Cesarim Mendonça, Fernando Freitas de Lima, Eneida de Paula   +6 more
doaj   +1 more source