Results 11 to 20 of about 30,373 (294)
Biological screening of a unique drug library targeting MRGPRX2
Frontiers in Immunology, 2022 BackgroundAllergic drug reaction or drug allergy is an immunologically mediated drug hypersensitivity reaction (DHR). G-protein coupled receptors (GPCRs) are common drug targets and communicate extracellular signals that initiate cellular responses ...
Fan Yang +8 more
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Ceftazidime and cefepime antagonize 5-fluorouracil’s effect in colon cancer cells
BMC Cancer, 2022 Background Drug-drug interaction (DDI), which can occur at the pharmacokinetics and/or the pharmacodynamics (PD) levels, can increase or decrease the therapeutic or adverse response of a drug itself or a combination of drugs.
Christina Pfab +6 more
doaj +1 more source
Antibiotics, 2021 Bloodstream infections (BSI) are a severe complication of antineoplastic chemotherapy or hematopoietic stem cell transplantation (HSCT), especially in the presence of antibiotic resistance (AR).
Elio Castagnola +23 more
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Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine [PDF]
, 2020 The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites.
Amoozegar, Mohammad Ali +2 more
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Frontiers in Pharmacology, 2023 Drug-induced acute kidney injury (DI-AKI) is one of the leading causes of kidney injury, is associated with high mortality and morbidity, and limits the clinical use of certain therapeutic or diagnostic agents, such as antineoplastic drugs, antibiotics ...
Jun Li +4 more
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Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds
Antibiotics, 2022 Microorganisms are known as important sources of natural compounds that have been studied and applied for different purposes in distinct areas. Specifically, in the pharmaceutical area, fungi have been explored mainly as sources of antibiotics, antiviral,
Rafael Conrado +3 more
doaj +1 more source
Desensitization for the prevention of drug hypersensitivity reactions [PDF]
The Korean Journal of Internal Medicine, 2022 Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang +2 more
doaj +1 more source
An overview of diagnosis and management of drug‐induced hypomagnesemia
Pharmacology Research & Perspectives, 2021 Magnesium (Mg) is commonly addressed as the “forgotten ion” in medicine. Nonetheless, hypomagnesemia should be suspected in clinical practice in patients with relevant symptomatology and also be considered a predisposing factor for the development of ...
George Liamis +3 more
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Comprehensive Analysis of Chemotherapeutic Agents That Induce Infectious Neutropenia
Pharmaceuticals, 2021 Chemotherapy-induced neutropenia (CIN) has been associated with a risk of infections and chemotherapy dose reductions and delays. The chemotherapy regimen remains one of the primary determinants of the risk of neutropenia, with some regimens being more ...
Mashiro Okunaka +4 more
doaj +1 more source
European surveillance of infections in cancer patients - ESIC [PDF]
, 1999 Major advances in cancer therapy result from development of multidrug chemotherapy regimens. Besides death from tumor progression, infections are currently one of the major causes of mortality and morbidity.
Buchheidt, D. +7 more
core +1 more source