Interactions of beta-lactam antibiotics and antineoplastic agents [PDF]
The in vitro interactions of four beta-lactam antibiotics and five antineoplastic agents were examined with 100 clinically isolated strains of four species of gram-negative bacilli. Generally, by the checkerboard dilution method, beta-lactam antibiotics, when tested in combination with mitomycin C, bleomycin, or 5-fluorouracil, showed synergistic ...
Saikawa Isamu+7 more
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Efficacy of antineoplastic treatment is associated with the use of antibiotics that modulate intestinal microbiota [PDF]
Reduced anticancer efficacy of cyclophosphamide and platinum salts has been reported in animals treated with anti-Gram-positive antibiotics. These effects were related to translocation of Gram-positive bacteria during mucositis with subsequent induction of cytotoxic oxygen reactive species and tumor invasion by pathogenic Th17 cells.
P. Cramer+14 more
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The increasing number of life-threatening infections observed in cancer patients has been ascribed to chemotherapy-induced neutropenia and to invasive medical procedures such as surgery and the application of catheters.
Carla C. C. R. de Carvalho
doaj +3 more sources
Acute Generalized Exanthematous Pustulosis in a 76-year-Old Man With Neuroendocrine Carcinoma of the Lung, Responsive to Ixekizumab. [PDF]
Jing Zhang,* Yue Chen,* Duanni Xu, Shaoyin Ma, Yichuan Gan, Yuwu Luo Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yue Chen; Yuwu Luo, Guangzhou ...
Zhang J+5 more
europepmc +2 more sources
Due to limited new antibiotics, polymyxins are increasingly used to treat multidrug-resistant (MDR) Gram-negative bacteria, in particular carbapenem-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.
Thien B. Tran+9 more
doaj +2 more sources
Disseminated Marginal Zone Lymphoma in a Patient with Lyme Neuroborreliosis: A Case Report. [PDF]
Introduction: Lyme borreliosis has been associated with lymphoma, particularly cutaneous lymphomas. The literature is conflicted regarding the effect of antibiotic therapy in cutaneous marginal zone lymphomas (MZLs) in individuals with ...
Weisbjerg DK+5 more
europepmc +2 more sources
Clinical characteristics and risk factors analysis of 505 cases of infusion reactions in a tertiary hospital. [PDF]
Background: The clinical characteristics and risk factors of infusion reactions (IRs) are inadequately described in clinical practice due to underreported cases.
Yin W+9 more
europepmc +2 more sources
Application of Optical Methods for Determination of Concentration of Doxorubicin in Blood and Plasma
The aim of presented research is to develop a simple and quick method of spectrophotometric detection for the determination of doxorubicin hydrochloride in blood and plasma.
Tomasz Sikora+4 more
doaj +1 more source
Effects of Concomitant Antibiotics Use on Immune Checkpoint Inhibitor Efficacy in Cancer Patients
Objective Immune checkpoint inhibitors (ICIs) have changed the outcomes of a variety of cancers in an unprecedented manner. Gut microbiome plays a crucial regulatory role in the antineoplastic therapy of ICIs, which can be influenced by antibiotic (ABX ...
Shuai Jiang+8 more
semanticscholar +1 more source
Analysis of 12 cases of antineoplastic agents-induced interstitial lung disease
Objective: To summarize the situation of antineoplastic agents-induced interstitial lung diseases (ILD), provide reference for strengthening clinical management of druginduced interstitial lung diseases (DILD).Methods: We retrospectively investigated the
Xiao Li+4 more
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