Results 181 to 190 of about 842,782 (192)

Antimicrobial and Antitubercular Activity of Endophytic Actinobacterium and Streptomyces Sp. SACC 4 Isolated from the Mangrove Plant, Rhizophora apiculate

, 2020
Public health threat due to drug resistant pathogens like Mycobacterium tuberculosis and others necessitates the discovery of novel antibiotics. Actinobacteria from understudied sources is emerging as promising source for novel molecules effective ...
Ayswarya, S
semanticscholar   +1 more source

Quinoline Hydrazide/Hydrazone Derivatives: Recent Insights on Antibacterial Activity and Mechanism of Action

ChemMedChem, 2023
Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater difficulty in the treatment of infectious diseases. Therefore, the development of new chemical entities with different mechanisms of action is essential in the ...
S. Verma, S. Lal, R. Narang, Kalvatala Sudhakar   +3 more
semanticscholar   +1 more source

Recent Developments in Azole Compounds as Antitubercular Agent

Mini-Reviews in Organic Chemistry, 2019
Tuberculosis (TB) is a global health disaster and is a wide-reaching hitch. The improper use of antibiotics in chemotherapy of TB patients led to the current problem of tuberculosis therapy which gives rise to Multi-Drug Resistant (MDR) strains. Nitrogen
R. Das, G. S. Asthana, K. A. Suri, D. Mehta, Abhay Asthana   +4 more
semanticscholar   +1 more source

Structural Basis for the Interaction and Processing of β-Lactam Antibiotics by l,d-Transpeptidase 3 (LdtMt3) from Mycobacterium tuberculosis.

ACS Infectious Diseases, 2019
Targeting Mycobacterium tuberculosis peptidoglycans with β-lactam antibiotics represents a strategy to address increasing resistance to antitubercular drugs.
G. A. Libreros-Zúñiga, Catharina Dos Santos Silva, Rafaela Salgado Ferreira, M. Dias   +3 more
semanticscholar   +1 more source

Design, Synthesis and Antitubercular Evaluation of Novel Series of Pyrazinecarboxamide Metal Complexes

Iranian journal of pharmaceutical research, 2018
The interest in the synthesis of metallic complexes of different drugs to make them more efficient in biological environment of the human body is seen for the last few decades.
Mohsin Ali, Mansoor M Ahmed, S. Hafiz, M. Kamal, M. Mumtaz, S. A. Ayatollahi   +5 more
semanticscholar   +1 more source

Evaluation of a novel inhibitor of aspartate semialdehyde dehydrogenase as a potent antitubercular agent against Mycobacterium tuberculosis

Journal of antibiotics (Tokyo. 1968), 2022
Ru-Song Yang, W. Cao, Shengsheng Liu, Qiao Li, Yong Sun, C. Liang, Weicong Ren, Yi Liu, Jianzhou Meng, Chuanyou Li   +9 more
semanticscholar   +1 more source

Antibiotics from higher plants: pteleatinium chloride, a new quaternary quinoline alkaloid from Ptelea trifoliata with antitubercular and antiyeast activity

, 1971
L. Mitscher, M. Bathala, J. Beal
semanticscholar   +1 more source

Oxidative Cyclization of Isoniazid with Fluoroquinolones: Synthesis, Antibacterial and Antitubercular Activity of New 2,5‐disubstituted‐1,3,4‐Oxadiazoles

, 2017
Shahalam Khan, P. Ahuja, A. Husain
semanticscholar   +1 more source

Systematic Review of New Trends in Antitubercular Synthesis and Analysis

, 2019
B. Dackouo, D. P. Arama
semanticscholar   +1 more source

NRPS substrate promiscuity leads to more potent antitubercular sansanmycin analogues.

Journal of Natural Products, 2014
Yunying Xie, Qiang Cai, Hao Ren, Lifei Wang, Hongzhang Xu, B. Hong, Linzhuan Wu, Ruxian Chen   +7 more
semanticscholar   +1 more source