Results 171 to 180 of about 10,695 (225)
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Capreomycin — A polypeptide antitubercular antibiotic with unusual binding properties toward copper(II)

Journal of Inorganic Biochemistry, 2012
Capreomycin is an important therapeutic agent having intriguing and diverse molecular features. Its polypeptidic structure rich in nitrogen donors makes the drug a promising chelating agent for a number of transition metal ions, especially for copper(II).
Stokowa K.   +5 more
openaire   +3 more sources

Novel Benzoxazoles: Synthesis and Antibacterial, Antifungal, and Antitubercular Activity against Antibiotic-Resistant and -Sensitive Microbes

Zeitschrift für Naturforschung C, 2013
A new series of 5-(p-substituted benzamido/phenylacetamido)-2-(p-tert-butylphenyl)benzoxazole derivatives were synthesized and evaluated for their antibacterial, antifungal, and antimycobacterial activities against antibiotic-resistant and -sensitive Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, and ...
Arisoy, Mustafa   +3 more
openaire   +3 more sources

Shape based Virtual Screening and Discovery of Potential Antitubercular Activity in 'Non-antibiotics'

International Journal of Drug Design and Discovery
Tuberculosis is an age-old debilitating infectious disease caused by the microbe Mycobacterium tuberculosis. Despite the efforts made by international community, this ancient scourge could not contain. Lipid rich cell wall, very active resistance development mechanisms and ability to switch to a quiescent stage inside the host tissues made anti TB drug
Muthyala Murali Krishna Kumar   +4 more
openaire   +1 more source

[The current epidemiologic profile of the drug resistance of Koch's bacillus to antitubercular antibiotic chemicals].

Minerva medica, 1990
The study was conducted on patients with initially diagnosed tuberculosis encountered in 1986-87. A series of 269 bacterial antibiograms performed on sputum [correction of excreate] and other materials was examined in order to ascertain the resistance of Koch's bacillus to R/AMP, INH, SM and EMB. Primary drug resistance was found in 64 cases (23.79% of
S, Giove   +6 more
openaire   +1 more source

Tackling antibiotic resistance in M. tuberculosis - design and synthesis of novel antitubercular small molecules

2017
As the cause of 1.7 million deaths in 2016 , M. Tuberculosis (MTB) represents a serious global threat to those infected. Growing numbers of multidrug-resistant (MDR) specimen increase the urgency of improving existing treatment, as well as developing new mechanisms of inhibition. This study covers an approach of tackling MDR- M.
openaire   +1 more source

Carbon-13 nuclear magnetic resonance studies on a new antitubercular peptide antibiotic LL-BM547.beta.

The Journal of Organic Chemistry, 1977
W J, McGahren   +3 more
openaire   +2 more sources

Antitubercular potential of plants: A brief account of some important molecules

Medicinal Research Reviews, 2010
Arvind S Negi, Suaib Luqman
exaly  

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