Results 111 to 120 of about 1,881,968 (357)

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Antibiotics in crisis [PDF]

Current Biology, 2013
SummaryBacterial infections resistant to antibiotics kill 23,000 people per year in the US alone, a recent report warns. This crisis is man-made, as misuse of the miracle drugs over decades has thrown away their life-saving potential. Michael Gross reports.
openaire   +3 more sources

PK/PD Modeling as a Tool for Predicting Bacterial Resistance to Antibiotics: Alternative Analyses of Experimental Data

Антибиотики и Химиотерапия, 2020
Postexposure number of mutants (NM) is a conventional endpoint in bacterial resistance studies using in vitro dynamic models that simulate antibiotic pharmacokinetics.
M. V. Golikova, E. N. Strukova, Y. A. Portnoy, A. A. Firsov   +3 more
doaj  

Diastereoselective Synthesis of Spirocyclopropanes under Mild Conditions via Formal [2 + 1] Cycloadditions Using 2,3-Dioxo-4-benzylidene-pyrrolidines

Molecules, 2017
A highly diastereoselective cyclopropanation of cyclic enones with sulfur ylides was developed under catalyst-free conditions, producing multifunctional spirocyclopropanes in generally excellent yields (up to 99% yield and >99:1 d.r.).
Yi Li, Qing-Zhu Li, Li Huang, Hong Liang, Kai-Chuan Yang, Hai-Jun Leng, Yue Liu, Xu-Dong Shen, Xiao-Jun Gou, Jun-Long Li   +9 more
doaj   +1 more source

Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances

Frontiers in Microbiology, 2016
The human microbiome is overly exposed to antibiotics, due, not only to their medical use, but also to their utilization in farm animals and crops. Microbiome composition can be rapidly altered by exposure to antibiotics, with potential immediate effects
P. Mullany, Polpass Arul, José, M. P. Francino   +3 more
semanticscholar   +1 more source

Studies on Antibiotics and Related Substances. VI. Configurations of Isomeric O-Methylphenylserines and a New Route for the Synthesis of Chloramphenicol [PDF]

, 1957
Tetsuo Suami, Sumio Umezawa
openalex   +1 more source

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

Advanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na, Yubeen Park, Hyun Lee, Song Hee Kim, Seojoon Bang, Hyeong Seok Kang, Chan Ho Moon, Ju Yeong Gwon, Jong Hwa Seo, Min‐Ho Kang, Soo‐Hong Lee, Gi Doo Cha, Wooram Park, Heemin Kang, Jung‐Hoon Park, Hyun‐Do Jung   +15 more
wiley   +1 more source

Clinical characteristics and antimicrobial therapy of healthcare-associated carbapenem-non-susceptible gram-negative bacterial meningitis: a 16-year retrospective cohort study

BMC Infectious Diseases
Objective Healthcare-associated Gram-negative bacterial meningitis is a substantial clinical issue with poor outcomes, especially for neurosurgical patients.
Jiyan Xu, Xiaoling Du, Dan Li, Pei Li, Qinglan Guo, Xiaogang Xu, Fupin Hu, Minggui Wang   +7 more
doaj   +1 more source

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

Genome Medicine, 2016
The widespread use of antibiotics in the past 80 years has saved millions of human lives, facilitated technological progress and killed incalculable numbers of microbes, both pathogenic and commensal.
A. Langdon, Nathan Crook, G. Dantas
semanticscholar   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source