Results 111 to 120 of about 2,598,203 (404)
Acute Respiratory Tract Infections and How to Treat Them [PDF]
, 2019 Acute respiratory tract infections (ARTIs) are one of the most common clinical encounters in primary care settings and they often lead to antibiotic prescriptions. However, more than 90% of ARTIs are caused by viral syndromes.
Seth, Shivani
core +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
FEBS Open Bio, EarlyView.This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance
World journal of gastrointestinal pharmacology and therapeutics, 2017 The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Derek M Lin, B. Koskella, Henry C. Lin
semanticscholar +1 more source
The future of antibiotics [PDF]
Critical Care, 2014 AbstractAntibiotic resistance continues to spread even as society is experiencing a market failure of new antibiotic research and development (R&D). Scientific, economic, and regulatory barriers all contribute to the antibiotic market failure.
Brad Spellberg, Brad Spellberg
openaire +3 more sources
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach +11 more
wiley +1 more source
Antibiotics, gut microbiota, and Alzheimer’s disease
Journal of Neuroinflammation, 2019 Alzheimer’s disease (AD) is a neurodegenerative disease whose various pathophysiological aspects are still being investigated. Recently, it has been hypothesized that AD may be associated with a dysbiosis of microbes in the intestine.
F. Angelucci +3 more
semanticscholar +1 more source
Antibiotics in the clinical pipeline in October 2019
Journal of antibiotics (Tokyo. 1968), 2020 The development of new and effective antibacterial drugs to treat multi-drug resistant (MDR) bacteria, especially Gram-negative (G−ve) pathogens, is acknowledged as one of the world’s most pressing health issues; however, the discovery and development of
M. Butler, D. Paterson
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat +8 more
wiley +1 more source
Антибиотики и Химиотерапия, 2020 Biological properties of new synthetic triindolylmethylium antibiotics of the triindolylmethane group, including compounds containing a maleimide fragment in the structure, are studied.
E. P. Mirchink +8 more
doaj
Parents' beliefs and knowledge about the management of acute otitis media: A qualitative study [PDF]
, 2015 BACKGROUND: Acute otitis media is a common reason for antibiotic prescribing, despite strong evidence that antibiotics provide minimal benefit. Studies have demonstrated that patients’ (or parents’) expectations of antibiotics often influence general ...
Del Mar, Chris +3 more
core +2 more sources