The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling [PDF]
, 2014 Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole.
Bastidas, Robert J. +6 more
core +9 more sources
Altered functionality of anti-bacterial antibodies in patients with chronic hepatitis C virus infection. [PDF]
PLoS ONE, 2013 Using comparative glycoproteomics, we have previously identified a glycoprotein that is altered in both amount and glycosylation as a function of liver cirrhosis.
Anne Lamontagne +9 more
doaj +1 more source
Presence of anti-microbial antibodies in liver cirrhosis--a tell-tale sign of compromised immunity? [PDF]
PLoS ONE, 2010 BACKGROUND: Bacterial translocation plays important role in the complications of liver cirrhosis. Antibody formation against various microbial antigens is common in Crohn's disease and considered to be caused by sustained exposure to gut microflora ...
Maria Papp +17 more
doaj +1 more source
Di-san junyi daxue xuebao, 2020 Objective To investigate the ability of specific polyclonal antibodies against Staphylococcus aureus (S. aureus) lipoprotein SA2275 to penetrate the blood-brain barrier for inhibiting the formation of S. aureus-induced brain abscess in mice.
ZHENG Ying +3 more
doaj +1 more source
Antibodies against bacterial membrane proteins [PDF]
Journal of Endotoxin Research, 1999 Prior studies have shown that antiserum raised to the Escherichia coli J5 vaccine binds to three bacterial outer membrane proteins (OMPs) that are present on serum-exposed smooth Enterobacteriaceae and in LPS-containing fragments that are released by bacteria incubated in human serum.
H. Shaw Warren, Judith Hellman
openaire +2 more sources
Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]
, 1991 " An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core +1 more source
Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]
, 2017 Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita +13 more
core +1 more source
Disease-Enhancing Antibodies Improve the Efficacy of Bacterial Toxin-Neutralizing Antibodies [PDF]
Cell Host & Microbe, 2013 During infection, humoral immunity produces a polyclonal response with various immunoglobulins recognizing different epitopes within the microbe or toxin. Despite this diverse response, the biological activity of an antibody (Ab) is usually assessed by the action of a monoclonal population.
Mary Ann Pohl +5 more
openaire +3 more sources
Clinical and Developmental Immunology, 2008 We previously demonstrated that purified polyclonal and monoclonal anti-dsDNA antibodies bind a 15-mer peptide ASPVTARVLWKASHV in ELISA and Dot blot. This 15-mer peptide partial sequence ARVLWKASH shares similarity with burkholderia bacterial cytochrome ...
Wei Zhang, Morris Reichlin
doaj +1 more source
Utility of serological markers in inflammatory bowel diseases: Gadget or magic? [PDF]
, 2007 The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Although anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely ...
Altorjay, István +3 more
core +1 more source