Antibodies and IL-3 support helminth-induced basophil expansion [PDF]
Proceedings of the National Academy of Sciences, 2012 Basophils are powerful mediators of Th2 immunity and are present in increased numbers during allergic inflammation and helminth infection. Despite their ability to potentiate Th2 immunity the mechanisms regulating basophil development remain largely ...
Bourquin, Carole +14 more
core +7 more sources
Broad specificity of immune helminth scFv library to identify monoclonal antibodies targeting Strongyloides [PDF]
Scientific Reports, 2021 Antibodies have different chemical properties capable of targeting a diverse nature of antigens. Traditionally, immune antibody libraries are perceived to be disease-specific with a skewed repertoire.
Anizah Rahumatullah +6 more
doaj +4 more sources
Maternally derived anti-helminth antibodies predict offspring survival in a wild mammal [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2020 The transfer of antibodies from mother to offspring provides crucial protection against infection to offspring during early life in humans and domestic and laboratory animals. However, few studies have tested the consequences of variation in maternal antibody transfer for offspring fitness in the wild.
Alexandra M. Sparks +7 more
openaire +5 more sources
Allergy, Asthma & Clinical Immunology, 2023 Helminth/tuberculosis (TB)-coinfection can reduce cell-mediated immunity against Mycobacterium tuberculosis (Mtb) and increase disease severity, although the effects are highly helminth species dependent.
Giggil Pushpamithran +8 more
doaj +1 more source
How to train your myeloid cells: a way forward for helminth vaccines?
Frontiers in Immunology, 2023 Soil-transmitted helminths affect approximately 1.5 billion people worldwide. However, as no vaccine is currently available for humans, the current strategy for elimination as a public health problem relies on preventive chemotherapy.
Rory Doolan +8 more
doaj +1 more source
Antibody-Based Protective Immunity against Helminth Infections: Antibody Phage Display Derived Antibodies against BmR1 Antigen [PDF]
International Journal of Molecular Sciences, 2017 Helminth parasite infections are significantly impacting global health, with more than two billion infections worldwide with a high morbidity rate. The complex life cycle of the nematodes has made host immune response studies against these parasites extremely difficult.
Anizah Rahumatullah +3 more
openaire +2 more sources
Context-dependent roles of B cells during intestinal helminth infection.
PLoS Neglected Tropical Diseases, 2021 The current approaches to reduce the burden of chronic helminth infections in endemic areas are adequate sanitation and periodic administration of deworming drugs.
Aidil Zaini +2 more
doaj +1 more source
Electrochemical detection of Toxocara canis excretory-secretory antigens in children from rural communities in Esmeraldas Province, Ecuador: association between active infection and high eosinophilia. [PDF]
, 2020 BACKGROUND: The diagnosis of active Toxocara canis infections in humans is challenging. Larval stages of T. canis do not replicate in human tissues and disease may result from infection with a single T. canis larva.
Chico, M +9 more
core +3 more sources
Thoughts underlying “pneumonia” resulting from eating: A case report
Respiratory Medicine Case Reports, 2023 As a rare zoonotic helminth disease, paragonimiasis is easy to be misdiagnosed. Adequate attention to the medical history of the patient and early detection of serological antibodies can improve the diagnosis rate. Praziquantel and trichlorobendazole are
Shu-Qin Fei
doaj +1 more source
Human ascariasis: diagnostics update [PDF]
, 2015 Soil-transmitted helminths (STHs) infect over one billion people worldwide. Ascariasis may mimic a number of conditions, and individual clinical diagnosis often requires a thorough work-up.
Jourdan, Peter M., Lamberton, Poppy H.L.
core +1 more source