Results 61 to 70 of about 23,804 (223)

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source

Eosinophils Control Liver Damage by Modulating Immune Responses Against Fasciola hepatica

Frontiers in Immunology, 2020
Eosinophils are granulocytes that participate in the defense against helminth parasites and in hypersensitivity reactions. More recently, eosinophils were shown to have other immunomodulatory functions, such as tissue reparation, metabolism regulation ...
Sofía Frigerio, Valeria da Costa, Monique Costa, María Florencia Festari, Mercedes Landeira, Santiago A. Rodríguez-Zraquia, Steffen Härtel, Jorge Toledo, Teresa Freire   +8 more
doaj   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Efficacy of an enzyme-linked immunosorbent assay as a diagnostic tool for schistosomiasis mansoni in individuals with low worm burden

Memorias do Instituto Oswaldo Cruz, 2005
IgM-ELISA is an immunoenzymatic method useful for detection of IgM antibodies against a fraction of Schistosoma mansoni adult worm antigen (AWA) that is soluble in trichloroacetic acid (AWA-TCA).
Edward José de Oliveira, Hermínia Yohko Kanamura, Dirce Mary Correia Lima   +2 more
doaj   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 733-737, March 2026.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss, Amanda V. Karam, Julia Shalen, David E. Tunkel, Belina Y. Yi, Kelsey S. Guthrie, Emily M. Kudalkar, Anna E. Patrick, Sonja A. Rasmussen   +8 more
wiley   +1 more source

Mucosal Mast Cells Response in the Jejunum of Ascaridia Galli-Infected Laying Hens [PDF]

, 2013
Intestinal defense mechanism against helminthes parasitic nematode to be associated with mucosal mast cells reaction. The aim of this research was to examine the effect of infection by Ascaridia galli parasite to trigger mucosal defense based on mucosal ...
Balqis, U. (U), Darmawi, D. (Darmawi), Frengki, F. (Frengki), Hambal, M. (M), Priosoeryanto, B. P. (B)   +4 more
core  

Cellular networks controlling Th2 polarization in allergy and immunity [PDF]

, 2012
In contrast to the development of Th1 (type 1 T helper cells), Th17 and Treg (regulatory T cells), little is known of the mechanisms governing Th2 development, which is important for immunity to helminths and for us to understand the pathogenesis of ...
Kool, Mirjam, Hammad, Hamida, Lambrecht, Bart   +2 more
core   +1 more source

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

MedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song, Yazhi Mo, Si Chen, Yuemei Chen, Chunying Zhang, Shanying Deng, Juan Liao, Yi He, Wei Wang, Weidong Zheng, Tingting Zeng   +10 more
wiley   +1 more source

Seroprevalence and Risk Factors of Cystic Echinococcosis in Cattle and Buffaloes: Insights From an In‐House ELISA

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
This study reveals widespread exposure to Echinococcus granulosus in cattle and buffaloes across Punjab, Pakistan (overall seroprevalence 45.81%), with marked geographic, species, age, sex and breed‐related differences. Findings highlight high‐risk areas and support targeted, One Health–based surveillance and control strategies.
Mughees Aizaz Alvi, Talha Javaid, Majed H. Wakid, Hong‐Bin Yan, Muhammad Wasim Usmani, Li Li, Warda Qamar, Aliza Ali, Junaid Amjed, Wan‐Zhong Jia, Muhammad Saqib   +10 more
wiley   +1 more source

Helminth Seropositivity Inversely Correlated with Th1 and Th17 Cytokines and Severe COVID-19

Vaccines
Background/Objectives: The COVID-19 pandemic has significantly impacted global health. However, Africa has reported relatively low numbers of cases and fatalities.
Brice Armel Nembot Fogang, Julia Meyer, Linda B. Debrah, Michael Owusu, George Agyei, Derrick Adu Mensah, John Boateng, Jubin Osei Mensah, Ute Klarmann-Schulz, Sacha Horn, Inge Kroidl, Ezekiel Bonwin Ackah, Richard O. Phillips, Augustina Sylverken, Alexander Y. Debrah, Achim Hoerauf, Tomabu Adjobimey   +16 more
doaj   +1 more source