Results 151 to 160 of about 652,488 (245)

Rapid Glass‐Substrate Digital Light 3D Printing Enables Anatomically Accurate Stroke Patient‐Specific Carotid Artery‐on‐Chips for Personalized Thrombosis Investigation

Advanced Materials, EarlyView.
A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao, Zihao Wang, Arian Nasser, Allan Sun, Zhao Wang, Yingqi Zhang, Jianfang Ren, Haimei Zhao, Nicole Alexis Yap, Yinyan Wang, Zhiyong Li, Ken S Butcher, Freda Passam, Timothy Ang, Lining Arnold Ju   +14 more
wiley   +1 more source

Development of the novel Pictor PictVet™ <i>Mycoplasma bovis</i> IgG multiplex ELISA for the detection of <i>Mycoplasma bovis</i> infections in cattle. [PDF]

Front Vet Sci
Furuya Y, Bugde P, Shetty B, Hashimi FN, Gholizadeh H, Whittaker D, Tejerina J, Gordon N, Tivendale KA, Wawegama NK, Browning GF, Kinga A.   +11 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Revolutionizing cancer therapy: Monoclonal antibodies in radiosensitization. [PDF]

Bioimpacts
Bemidinezhad A, Abolhassani Y, Noroozi-Karimabad M, Abroumand Gholami A, Alalikhan A, Roshani R, Parsa-Kondelaji M, Gheybi F.   +7 more
europepmc   +1 more source

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

Advanced Materials, EarlyView.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae, Hyunsub Ji, Konstantin Konstantinov, Ronald Sluyter, Katsuhiko Ariga, Yong Ho Kim, Jung Ho Kim   +6 more
wiley   +1 more source

Social media insights on the introduction of RSV immunoprophylaxis in Italy. [PDF]

Hum Vaccin Immunother
Gesualdo F, Casigliani V, Arzilli G, De Vita E, Porretta AD, Croci I, Carrozzo A, Bartolucci V, Buquicchio C, Rizzo C.   +9 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Optimising Monoclonal Antibody Drug Development for Inflammatory Bowel Disease. [PDF]

Clin Exp Gastroenterol
Colwill M, Honap S, Danese S, Peyrin-Biroulet L.   +3 more
europepmc   +1 more source

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

Advanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng, Shiqiong Lei, Yiwei Zeng, Lian Chen, Jingqu Chen, Wei Fu, Yu Chen, Xinping Hu, Jing Wang, Meiyuan Jin, Zhichen Liu, Xiaofang Dai, Lei Liu, Wenshan He, Jiajing Zhou, Zhixing Lin, Frank Caruso, Jinghua Ren   +17 more
wiley   +1 more source

Prevalence of Resistance-Associated Mutations in RSV F Protein Against Monoclonal Antibodies Prior to Widespread Implementation: Findings From a Prospective German Pediatric Cohort. [PDF]

Influenza Other Respir Viruses
Wetzke M, Le DB, Tometten I, Ritter S, Lübke N, Timm J, Dilthey A, Panning M, Walker A, Happle C.   +9 more
europepmc   +1 more source