clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries. [PDF]
Mitchell K+5 more
europepmc +1 more source
3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration
A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano+4 more
wiley +1 more source
Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon‐to‐Bone Repair
The authors have developed a biomimetic scaffold with dual gradients through a diffusion‐driven method. The scaffold features funnel‐shaped microchannels for cell infiltration, while the dual gradients synergetically induce the graded differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, and tenocytes, allowing for a seamless ...
Min Hao+3 more
wiley +1 more source
Editorial: Safety consideration in the development of anti-tumor monoclonal antibodies during drug development. [PDF]
Wang T, Abedin SE, van der Laan JW.
europepmc +1 more source
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban+5 more
wiley +1 more source
SARS-CoV-2 Spike S2 Refolding: Structural Insights and Inhibition Strategies Against Emerging Variants. [PDF]
Xu C, Xie W, Long X.
europepmc +1 more source
Monoclonal Antibodies in Dermatology [PDF]
openaire +2 more sources
Machine‐Learning‐Aided Advanced Electrochemical Biosensors
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan+9 more
wiley +1 more source
Polyclonal LC3B Antibodies Generate Non-Specific Staining in the Nucleus of Herpes Simplex Virus Type 1-Infected Cells: Caution in the Interpretation of LC3 Staining in the Immunofluorescence Analysis of Viral Infections. [PDF]
Ripa I+5 more
europepmc +1 more source
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang+17 more
wiley +1 more source