Results 171 to 180 of about 652,488 (245)

Advances in Techniques for the Structure and Functional Optimization of Therapeutic Monoclonal Antibodies. [PDF]

Biomedicines
He C, Huang W, Wu X, Xia H.
europepmc   +1 more source

Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This work demonstrates the design, fabrication, and the first‐time test of a 2D photonic crystal surface for photonic resonator absorption microscopy. The designed surface uniformly enhances electromagnetic near fields, achieving > 100% improved detecting uniformity for surface‐captured AuNPs from a blocking biosensor assay aimed for detecting SARS‐CoV‐
Weinan Liu, Siyan Li, Edmond Chow, Seemesh Bhaskar, Ying Fang, Brian T. Cunningham   +5 more
wiley   +1 more source

Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL. [PDF]

Elife
Luo D, Zheng J, Lv S, Sheng R, Chen M, He X, Zhang X.   +6 more
europepmc   +1 more source

Early Pancreatic Cancer Diagnosis via Ultrasensitive THz Toroidal Metasensing

Advanced Photonics Research, EarlyView.
This study introduces a revolutionary terahertz metasurface biosensor using gold nanoparticles to boost sensitivity. It achieves precise detection of ultra‐low biomarker concentrations (1–1000 pg mL−1) with a 97.6 GHz/RIU sensitivity through optimized antibody binding.
Peng Wang, Mingming Jiang, Qingzhe Jia, Zhaofu Ma, Chenjie Liu, Hui Dai, Yanan Jiao, Liangli Cao, Jing Lou   +8 more
wiley   +1 more source

Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series. [PDF]

NPJ Precis Oncol
Xavier CB, Gouda MA, Tsimberidou AM.
europepmc   +1 more source

Biohybrid Actuators in Compact Arrangement with Embedded X Electrode

Advanced Robotics Research, EarlyView.
Selective control of multimuscle biohybrid actuators is crucial for achieving complex movements of biohybrid robots. In this study, embedded X electrodes are fabricated to selectively control multiple muscles, realizing the robotic finger's bidirectional movements.
Tingyu Li, Minghao Nie, Shoji Takeuchi
wiley   +1 more source

Development of an In-House Antigen ELISA Using Monoclonal and Polyclonal Antibodies Against an Isolated Canine Distemper Virus. [PDF]

Vet Med Sci
Kökkaya S, Göksu AG.
europepmc   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

Identification of linear B-cell epitopes on the gE envelope protein of varicella-zoster virus. [PDF]

Microbiol Spectr
Niu Y, Zhou J, Liu Y, Wang H, Liu H, Chen Y, Zhu X, Liang C, Wang A.   +8 more
europepmc   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source