Results 231 to 240 of about 2,534,599 (334)

Monoclonal Antibodies in the Pathogenesis of Heparin-Induced Thrombocytopenia. [PDF]

N Engl J Med
Treverton J, Arnold DM, Ivanov DG, Ivetic N, Zhang Y, Ali HA, Clare R, Kaltashov IA, Kelton JG, Nazy I.   +9 more
europepmc   +1 more source

High‐Concentration Antibody Formulation via Solvent‐Based Dehydration

Advanced Materials, EarlyView.
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng, Lucas Attia, Janet Teng, Patrick S. Doyle   +3 more
wiley   +1 more source

Towards antibody-based immunotherapy development for platinum-resistant high-grade serous ovarian cancer. [PDF]

Sci Rep
Giedraityte Z, Aarnio N, Nait Mohamed FA.   +2 more
europepmc   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, EarlyView.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

Evaluation of multi-antigen targeting ADCC strategies in pediatric BCP-ALL. [PDF]

J Immunother Cancer
Grain A, Ollier J, Le Calvez B, Guiet E, Thomas C, Couec ML, Camuset M, Rialland F, Eveillard M, Scotet E, Clémenceau B.   +10 more
europepmc   +1 more source

Macrophages Mediate Mesoscale Brain Mechanical Homeostasis

Advanced Materials, EarlyView.
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So, Bailey Johnson, Patricia B. Gordon, Kevin S. Bishop, Hyeyeon Gong, Hannah A Burr, Jack Rory Staunton, Chenchen Handler, Khanh Loan Ly, Raman Sood, Giuliano Scarcelli, Kandice Tanner   +11 more
wiley   +1 more source

Correction to "Human IgE monoclonal antibodies define two unusual epitopes trapping dog allergen Can f 1 in different conformations". [PDF]

Protein Sci
europepmc   +1 more source

Innovative approaches in RSV prevention: The expanding role of monoclonal antibodies in protection for all infants. [PDF]

Germs
Mihălţan FD, Ulmeanu R, Nemeş RM, Petrea S, Streinu-Cercel A, Săndulescu O.   +5 more
europepmc   +1 more source

Monoclonal antibodies in acute lymphoblastic leukemia.

Blood, 2015
E. Jabbour, S. O'brien, F. Ravandi, H. Kantarjian   +3 more
semanticscholar   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

Advanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam, Jiao Zhai, Heng Zou, Yu Chen, Michael Yang   +4 more
wiley   +1 more source