Results 41 to 50 of about 3,666,403 (333)

Broad Epitope Coverage of Therapeutic Multi-Antibody Combinations Targeting SARS-CoV-2 Boosts In Vivo Protection and Neutralization Potency to Corner an Immune-Evading Virus

Biomedicines
Therapeutic antibodies (Abs) which act on a broader range of epitopes may provide more durable protection against the genetic drift of a target, typical of viruses or tumors.
Ilse Roodink, Maartje van Erp, Andra Li, Sheila Potter, Sander M. J. van Duijnhoven, Milou Smits, Arthur J. Kuipers, Bert Kazemier, Bob Berkeveld, Ellen van Geffen, Britte S. de Vries, Danielle Rijbroek, Bianca Boers, Sanne Meurs, Wieger Hemrika, Alexandra Thom, Barry N. Duplantis, Roland A. Romijn, Jeremy S. Houser, Jennifer L. Bath, Yasmina N. Abdiche   +20 more
doaj   +1 more source

Acknowledgement to Reviewers of Antibodies in 2017

Antibodies, 2018
Peer review is an essential part in the publication process, ensuring that Antibodies maintains high quality standards for its published papers.[...]
Antibodies Editorial Office
doaj   +1 more source

A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques [PDF]

, 2020
Human infection by Zika virus (ZIKV) during pregnancy can lead to vertical transmission and fetal aberrations, including microcephaly. Prophylactic administration of antibodies can diminish or prevent ZIKV infection in animal models, but whether passive ...
Agudelo, Marianna, Ardeshir, Amir, Balderes, Paul J., Bjorkman, Pamela J., Bournazos, Stylianos, Coffey, Lark L., Esswein, Shannon R., Gazumyanc, Anna, Immareddy, Ramya, Jurado, Andrea, Kapoor, Tania, Keeffe, Jennifer R., Keesler, Rebekah I., Lorenz, Ivo C., MacDonald, Margaret R., Nussenzweig, Michel C., Peace, Avery, Ravetch, Jeffrey V., Rice, Charles M., Robbiani, Davide F., Singapuri, Anil, Stuart, Jackson B., Usachenko, Jodie, Van Rompay, Koen K. A., Wang, Qiao, Watanabe, Jennifer   +25 more
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Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]

, 2005
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
H.P. Török, J. Glas, H.C. Hollay, R. Gruber, M. Osthoff, L. Tonenchi, C. Brückl, T. Mussack, M. Folwaczny, C. Folwaczny, Glas J, Quinton JF, Ruemmele FM, Cambridge G, Colombel JF, Shanahan F, Hoffman IE, Torok HP, Seibold F, Folwaczny C, Folwaczny C, Folwaczny C, Seibold F, Shanahan F, Folwaczny C, Bansi DS, Klebl FH, Klebl FH, Torok HP, Lombardi G   +29 more
core   +4 more sources

Acknowledgement to Reviewers of Antibodies in 2013

Antibodies, 2014
The editors of Antibodies would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013.
Antibodies Editorial Office
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Encephalitis with mGluR5 antibodies [PDF]

Neurology, 2018
To report the clinical features of 11 patients with metabotropic glutamate receptor 5 (mGluR5) antibody-associated encephalitis, immunoglobulin G (IgG) subclass, and effects of the antibodies on neuronal mGluR5 clusters.Clinical information was retrospectively obtained from referring physicians.
Spatola, Marianna, Sabater, Lidia, Heaney, Nicholas, Tubridy, Niall, Munteis Olivas, Elvira, Rosenfeld, Myrna R, Graus, Francesc, Dalmau, Josep, Planagumà, Jesús, Martínez-Hernandez, Eugenia, Armangué, Thaís, Prüss, Harald, Iizuka, Takahiro, Caparó Oblitas, Ruben L, Antoine, Jean-Christophe, Li, Richard   +15 more
openaire   +4 more sources

Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]

, 1993
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
DJ Garry, GF Bottazzo, GF Bottazzo, GS Eisenbarth, J Satoh, MA Atkinson, MR Christie, P Casali, PG Colman, R Gianani, RC Nayak, RJ Tuson, RL Sorenson, S Baekkeskov, S Baekkeskov, S Genovese, W Richter, W Richter, W Richter, WA Scherbaum   +19 more
core   +1 more source

The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent

Frontiers in Immunology, 2018
In spite of impressive response rates in multiple cancer types, immune checkpoint inhibitors (ICIs) are active in only a minority of patients. Alternative strategies currently aim to combine immunotherapies with conventional agents such as cytotoxic ...
Chloé Grasselly, Chloé Grasselly, Morgane Denis, Morgane Denis, Aurore Bourguignon, Aurore Bourguignon, Nolan Talhi, Doriane Mathe, Anne Tourette, Laurent Serre, Lars Petter Jordheim, Eva Laure Matera, Charles Dumontet, Charles Dumontet   +13 more
doaj   +1 more source

Mouse Models and Tools for the in vivo Study of Neutrophils

Frontiers in Immunology, 2020
Neutrophils are the most abundant leukocytes in human blood and critical actors of the immune system. Many neutrophil functions and facets of their activity in vivo were revealed by studying genetically modified mice or by tracking fluorescent ...
Julien Stackowicz, Julien Stackowicz, Friederike Jönsson, Laurent L. Reber, Laurent L. Reber   +4 more
doaj   +1 more source

Identification, Efficacy, and Stability Evaluation of Succinimide Modification With a High Abundance in the Framework Region of Golimumab

Frontiers in Chemistry, 2022
Succinimide (Asu) is the intermediate for asparagine deamidation in therapeutic proteins, and it can be readily hydrolyzed to form aspartate and iso-aspartate residues. Moreover, Asu plays an important role in the protein degradation pathways, asparagine
Tao Liu, Tao Liu, Tao Liu, Jin Xu, Jin Xu, Jin Xu, Jin Xu, Qingcheng Guo, Dapeng Zhang, Dapeng Zhang, Dapeng Zhang, Jun Li, Weizhu Qian, Weizhu Qian, Weizhu Qian, Huaizu Guo, Huaizu Guo, Huaizu Guo, Huaizu Guo, Xinli Zhou, Sheng Hou, Sheng Hou, Sheng Hou   +22 more
doaj   +1 more source