Results 51 to 60 of about 5,065,448 (337)

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

bioRxiv, 2020
Antibodies are becoming a frontline therapy for SARS-CoV-2, but the risk of viral evolutionary escape remains unclear. Here we map how all mutations to SARS-CoV-2’s receptor-binding domain (RBD) affect binding by the antibodies in Regeneron’s REGN-COV2 ...
Tyler N. Starr, Allison J. Greaney, A. Addetia, William W. Hannon, M. Choudhary, A. Dingens, Jonathan Z. Li, J. Bloom   +7 more
semanticscholar   +1 more source

Acknowledgement to Reviewers of Antibodies in 2013

Antibodies, 2014
The editors of Antibodies would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013.
Antibodies Editorial Office
doaj   +1 more source

Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]

, 1993
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
DJ Garry, GF Bottazzo, GF Bottazzo, GS Eisenbarth, J Satoh, MA Atkinson, MR Christie, P Casali, PG Colman, R Gianani, RC Nayak, RJ Tuson, RL Sorenson, S Baekkeskov, S Baekkeskov, S Genovese, W Richter, W Richter, W Richter, WA Scherbaum   +19 more
core   +1 more source

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil. [PDF]

, 2019
Zika virus infection is associated with the development of Guillain-Barré syndrome (GBS), a neurological autoimmune disorder caused by immune recognition of gangliosides and other components at nerve membranes.
Alcantara, Luiz Carlos Junior, de Siqueira, Isadora Cristina, do Rosário, Mateus Santana, Ernst, Joel D, Mota, Sabrina, Pereira de Jesus, Pedro Antônio, Rivera-Correa, Juan, Rodriguez, Ana   +7 more
core   +1 more source

The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent

Frontiers in Immunology, 2018
In spite of impressive response rates in multiple cancer types, immune checkpoint inhibitors (ICIs) are active in only a minority of patients. Alternative strategies currently aim to combine immunotherapies with conventional agents such as cytotoxic ...
Chloé Grasselly, Chloé Grasselly, Morgane Denis, Morgane Denis, Aurore Bourguignon, Aurore Bourguignon, Nolan Talhi, Doriane Mathe, Anne Tourette, Laurent Serre, Lars Petter Jordheim, Eva Laure Matera, Charles Dumontet, Charles Dumontet   +13 more
doaj   +1 more source

Mouse Models and Tools for the in vivo Study of Neutrophils

Frontiers in Immunology, 2020
Neutrophils are the most abundant leukocytes in human blood and critical actors of the immune system. Many neutrophil functions and facets of their activity in vivo were revealed by studying genetically modified mice or by tracking fluorescent ...
Julien Stackowicz, Julien Stackowicz, Friederike Jönsson, Laurent L. Reber, Laurent L. Reber   +4 more
doaj   +1 more source

Identification, Efficacy, and Stability Evaluation of Succinimide Modification With a High Abundance in the Framework Region of Golimumab

Frontiers in Chemistry, 2022
Succinimide (Asu) is the intermediate for asparagine deamidation in therapeutic proteins, and it can be readily hydrolyzed to form aspartate and iso-aspartate residues. Moreover, Asu plays an important role in the protein degradation pathways, asparagine
Tao Liu, Tao Liu, Tao Liu, Jin Xu, Jin Xu, Jin Xu, Jin Xu, Qingcheng Guo, Dapeng Zhang, Dapeng Zhang, Dapeng Zhang, Jun Li, Weizhu Qian, Weizhu Qian, Weizhu Qian, Huaizu Guo, Huaizu Guo, Huaizu Guo, Huaizu Guo, Xinli Zhou, Sheng Hou, Sheng Hou, Sheng Hou   +22 more
doaj   +1 more source

Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders [PDF]

, 2019
The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically improved the diagnosis of this disease and its distinction from multiple sclerosis.
Abril-Jaramillo, Javier, Casado Chocán, José Luis, Díaz Sánchez, María, Echevarría Irusta, Miriam, García Miranda, Pablo, García Sánchez, María Isabel, Lamas-Pérez, Lucía, Lebrato-Hernández, Lucía, Martínez Olivo, María del Mar, Morón Civanto, Francisco Jesús, Navarro, Gemma, Ramírez Lorca, Reposo, Romera, Mercedes, Suárez-Luna, Nela, Uclés Sánchez, Antonio José   +14 more
core   +1 more source

Antibodies in Infants Born to Mothers With COVID-19 Pneumonia.

Journal of the American Medical Association (JAMA), 2020
This study describes results of IgM and IgG antibody testing from throat swabs of newborns born to mothers with COVID-19 pneumonia.
Hui Zeng, Chen Xu, Junli Fan, Yueting Tang, Qiaoling Deng, Wei Zhang, X. Long   +6 more
semanticscholar   +1 more source

Isolation methods determine human neutrophil responses after stimulation

Frontiers in Immunology, 2023
Studying neutrophils is challenging due to their limited lifespan, inability to proliferate, and resistance to genetic manipulation. Neutrophils can sense various cues, making them susceptible to activation by blood collection techniques, storage ...
Vanessa Krémer, Vanessa Krémer, Ophélie Godon, Pierre Bruhns, Friederike Jönsson, Friederike Jönsson, Luc de Chaisemartin, Luc de Chaisemartin, Luc de Chaisemartin   +8 more
doaj   +1 more source