Results 201 to 210 of about 177,431 (250)
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Antibody-dependent cell-mediated cytotoxicity in pigs
American Journal of Veterinary Research, 1982SUMMARY Development of antibody-dependent cell-mediated cytotoxicity (adcc) was studied in cells obtained from porcine fetal and neonatal tissues. Pulmonary washouts, hepatic tissues, splenic tissues, and neutrophil fractions of blood were sources of cells.
A, Zarkower +4 more
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Antibody-Dependent Cell-Mediated Cytotoxicity in Humans
The Journal of Immunology, 1975Abstract Mononuclear cells from human peripheral blood are able to destroy alloantibody-coated target cells of a human lymphoblastoid line. The effector cell is a nonadherent, non-phagocytic, medium sized lymphoid cell. This cell is not detectable in early human fetuses.
Giorgio Trinchieri +3 more
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Damage of Liposomes in Antibody‐Dependent Cell‐Mediated Cytotoxicity
Scandinavian Journal of Immunology, 1977Lymphoid cells bearing Fc receptors are able to lyse antibody‐coated animal target Cells in an antibody‐dependent cell‐mediated cytotoxicity reaction. The results presented here show that liposomes consisting of sphingomyelin, cholesterol, and cardiolipid and coated by cardiolipidic antibodies could be destroyed by spleen or thymus cells. No alteration
D, Juy, A, Billecocq, M, Faure, C, Bona
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SELECTIVE REACTIONS IN ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
Transplantation, 1977Selective reactions associated with HLA specificity were sought in antibody-dependent cell-mediated cytotoxic tests against HLA-typed lymphoblastoid lines using operationally monospecific HLA sera and effector cells from healthy individuals. Precise detection of HLA specificities was disturbed by the presence of natural antibodies in HLA antiserum and ...
J, Takasugi, M, Takasugi
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Reversible blocking of antibody-dependent cell-mediated cytotoxicity
Cellular Immunology, 1977Abstract The ability of human peripheral blood lymphocytes to kill antibody-coated Chang liver cells in antibody-dependent cell-mediated cytotoxicity (ADCC) can be blocked with aggregated IgG (agg-IgG) or by soluble immune complexes. Dissociation of aggregates of IgG or immune complexes from the cell surface, however, resulted in partial recovery of ...
K, Sugamura, J B, Smith
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Enzymatic Enhancement of Cell-Mediated Cytotoxicity and Antibody-Dependent Cell Cytotoxicity
The Journal of Immunology, 1974Abstract The effects of papain, trypsin, Pronase, neuraminidase, and phospholipase C on in vitro cell-mediated cytotoxicity (CMC) and antibody-dependent cell cytotoxicity (ADCC) have been studied in a syngeneic tumor system. Proteolytic enzyme treatment of lymphoid (effector) cells at low concentrations (<0.1 mg/ml) and for short ...
E, Kedar +2 more
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Antibody-Dependent Lymphoid Cell-Mediated Cytotoxicity: Role of Complement
The Journal of Immunology, 1974Abstract Unsensitized lymphoid cells have the capacity to destroy antibody-coated target cells in vitro. Definitive studies to rule out the participation of complement (C) components in this reaction require a system with a complete absence of C components and with no possibility of endogenous synthesis of C by cells in culture.
J A, Van Boxel +3 more
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Influence of Hydrocortisone on Antibody-Dependent Lymphoid Cell Mediated Cytotoxicity
Immunological Communications, 1974Mice spleen lymphocytes which can be stimulated non-specifically by B cell mitogens such as lipopoly-saccharides (LPS) or a Nocardia water soluble mitogen (NWSM) are sensitive to cortisone. Experiments were performed in view of evaluating the influence of hydrocortisone on the lymphocyte-dependent antibody (LDA) cytotoxicity of mice spleen cells.
L, Chedid, D, Juy, C, Bona
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Antibody-dependent cell-mediated cytotoxicity (ADCC) in Aujeszky's disease
Archives of Virology, 1979Antibody-dependent cell-mediated cytotoxicity (ADCC) was studied using as targets 51Cr-labelled Vero cells infected with the Bartha strain of Aujeszky's disease virus (ADV). Using hyperimmune anti-ADV serum to sensitize the targets, porcine leukocytes from dextran-sedimented blood were found to be efficient effector cells yielding maximal 51Cr release ...
L A, Ashworth, G, Lloyd, A, Baskerville
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Journal of Visualized Experiments
The method for antibody-dependent, cell-mediated cytotoxicity (ADCC) represents an important tool to assess the efficacy of therapeutic antibodies in cancer immunotherapy. Evaluating ADCC activity in cancer cells is essential for the development and optimization of antibody-based treatments.
Kelvin Kam Yew, Kuan +4 more
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The method for antibody-dependent, cell-mediated cytotoxicity (ADCC) represents an important tool to assess the efficacy of therapeutic antibodies in cancer immunotherapy. Evaluating ADCC activity in cancer cells is essential for the development and optimization of antibody-based treatments.
Kelvin Kam Yew, Kuan +4 more
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