Results 231 to 240 of about 316,215 (308)

Preclinical characterisation of the protective capacity of an anti-nucleoprotein hRSV monoclonal antibody. [PDF]

EBioMedicine
Farías MA, Andrade CA, Loaiza RA, Rodríguez-Guilarte L, Muñoz JT, Pereira-Sánchez P, Muñoz-Durango N, Pizarro-Ortega MS, Diethelm-Varela B, Pereira-Serrano A, Ramírez RA, Chávez JL, Bohmwald K, Soto JA, González PA, Bueno SM, Kalergis AM.   +16 more
europepmc   +1 more source

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

JNK knockdown enhances CAR-T cell cytotoxicity through elevated NFATc1-dependent transcription in preclinical ovarian cancer models. [PDF]

J Immunother Cancer
Kuhlmann CJ, Jepson CE, Blucas MT, Suleiman FM, Manda A, Kamata YN, Kamata M.   +6 more
europepmc   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Therapeutic Potential of an Anti-CD44v6 Monoclonal Antibody in Xenograft Models of Colorectal and Gastric Cancer. [PDF]

Cells
Hirayama A, Tanaka T, Ohishi T, Shinoda K, Nakamura T, Nomura A, Kojo N, Araki H, Suzuki K, Kaneko MK, Suzuki H, Kato Y.   +11 more
europepmc   +1 more source

MMP-cleavable linker platform for tumour-responsive homo- and heterobivalent antibody-drug conjugates. [PDF]

Chem Sci
Counsell AJ, Walsh SJ, Ashman N, Park M, Dannheim FM, King TA, Wharton T, Carroll JS, Spring DR.   +8 more
europepmc   +1 more source

Exploring EGFR, Nectin-4, and TROP-2 as Therapeutic Targets for Bladder Cancer Photoimmunotherapy. [PDF]

Molecules
Wolf I, Giess N, Roider C, Schultze-Seemann S, Storz J, Werz DB, Miernik A, Gratzke C, Wolf P.   +8 more
europepmc   +1 more source

The Current Landscape of Modular CAR T Cells. [PDF]

Int J Mol Sci
Joechner AH, Mach M, Li Z.
europepmc   +1 more source