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Enhancement of antibody-dependent cellular phagocytosis of lymphoma cells by the blockade of HLA class I receptors

Antibody-dependent cellular phagocytosis (ADCP) of cancer cells by macrophages is a major mechanism of action of therapeutic antibodies. However, ADCP is hampered by the expression of ‘Don’t Eat Me!’ signals such as CD47 on tumor cells. In clinical studies in lymphoma patients, encouraging outcomes were obtained by combining the CD20 antibody rituximab
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Frontiers in Immunology, 2019
Kevin Wiehe   +2 more
exaly  

Neutrophils mediate HIV-specific antibody-dependent phagocytosis and ADCC

Journal of Immunological Methods, 2018
Adam J Lopez-Denman   +2 more
exaly  

CD47 limits antibody dependent phagocytosis against non-malignant B cells

Molecular Immunology, 2017
Yue Wang, Ronald Herbst, Susan Wilson
exaly  

Augmentation of human antibody-dependent cellular cytotoxicity and mononuclear phagocytosis by procaine.

Archives roumaines de pathologie experimentales et de microbiologie, 1985
A, Olinescu   +7 more
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