Frontiers in Immunology, 2017 The initiation, commitment, and terminal differentiation of the B cell lineage is stringently controlled by the coordinated action of various transcription factors.
Katrin Habir +3 more
doaj +1 more source
Induction of MET Receptor Tyrosine Kinase Down-Regulation through Antibody-Mediated Receptor Clustering [PDF]
, 2019 The proto-oncoprotein MET is a receptor tyrosine kinase that plays a key role in cancer cell growth and invasion. We have used fluorescence-tagged antibodies to activate MET in live serum-starved glioblastoma cells and monitor the fate of antibody-bound ...
Adam Dick +4 more
core +3 more sources
Prevalência de aloimunização eritrocitária em pacientes portadores de anemia falciforme
ABCS Health Sciences, 2017 Embora as transfusões de concentrado de hemácias sejam importantes para o tratamento de pacientes com anemia falciforme, elas acarretam riscos imunológicos tais como a aloimunização a antígenos eritrocitários.
Alexandre Gomes Vizzoni +1 more
doaj +1 more source
Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]
, 2003 Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike +9 more
core +1 more source
The role of HLA-DP mismatches and donor specific HLA-DP antibodies in kidney transplantation : a case series [PDF]
, 2021 BACKGROUND: The impact of HLA-DP mismatches on renal allograft outcome is still poorly understood and is suggested to be less than that of the other HLA loci.
Abramowicz, D +9 more
core +2 more sources
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]
, 1993 Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR +3 more
core +1 more source
Arthritis Research & Therapy, 2022 Background Neutrophil extracellular traps (NETs) are critically involved in microscopic polyangiitis (MPA) pathogenesis, and some patients with MPA possess anti-NET antibody (ANETA). Anti-myosin light chain 6 (MYL6) antibody is an ANETA that affects NETs.
Miku Yoshinari +15 more
doaj +1 more source
THE ANTIBODY-FORMATION BY POLYSACCHARIDS [PDF]
Journal of Experimental Medicine, 1929 1. By complement fixation tests, it has been clearly demonstrated that the sera of rabbits immunized with inulin, soluble starch and dextrine contain specific antibodies. 2. All these immune sera gave a negative precipitation reaction. 3.
openaire +3 more sources
ANTIBODY FORMATION IN VITRO [PDF]
The Journal of Experimental Medicine, 1961 Neutralizing activity against T2 bacteriophage appeared in cultures of lymph node cells from normal rats in response to their in vitro stimulation with a cell-free filtrate derived from homogenized rat macrophages which had been incubated with T2 bacteriophage. This activity was specifically directed against T2 bacteriophage.
openaire +3 more sources
High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein [PDF]
, 1994 Characterization of the assembly of lipoprotein(a) [Lp(a)] is of fundamental importance to understanding the biosynthesis and metabolism of this atherogenic lipoprotein. Since no established cell lines exist that express Lp(a) or apolipoprotein(a) [apo(a)
Azrolan N. +45 more
core +1 more source