Results 31 to 40 of about 7,305,993 (392)

Induction of MET Receptor Tyrosine Kinase Down-Regulation through Antibody-Mediated Receptor Clustering [PDF]

, 2019
The proto-oncoprotein MET is a receptor tyrosine kinase that plays a key role in cancer cell growth and invasion. We have used fluorescence-tagged antibodies to activate MET in live serum-starved glioblastoma cells and monitor the fate of antibody-bound ...
Adam Dick, Fei Lu, Hong Sun, Hui Zhang, Wenjing Li   +4 more
core   +3 more sources

High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein [PDF]

, 1994
Characterization of the assembly of lipoprotein(a) [Lp(a)] is of fundamental importance to understanding the biosynthesis and metabolism of this atherogenic lipoprotein. Since no established cell lines exist that express Lp(a) or apolipoprotein(a) [apo(a)
Azrolan N., Boerwinkle E., Brunner C., Chiesa G., Chung B. Y., Cotten M., Deutscher S. L., Deutscher S. L., Dieplinger H., Edelberg J. M., Green S., Griffiths G., Guevara J., Jr., Huby T., Ichinose A., Kamboh M. I., Koschinsky M. L., Koschinsky M. L., Koschinsky M. L., Kostner G. M., Kraft H- G., Kraft H. G., Krempler F., Krempler F., Lackner C., Linton M. F., Malgaretti N., McGregor G. R., McLean J. W., Menzel H. J., Phillips M. L., Rader D. J., Sambrook J., Sandholzer C., Scanu A. M., Selden R. F., Sommer A., Stanley P., Trieu V. N., Utermann G., Utermann G., Utermann G., Wagner E., White A. L., Zatloukal K., Zechner R„   +45 more
core   +1 more source

The role of HLA-DP mismatches and donor specific HLA-DP antibodies in kidney transplantation : a case series [PDF]

, 2021
BACKGROUND: The impact of HLA-DP mismatches on renal allograft outcome is still poorly understood and is suggested to be less than that of the other HLA loci.
Abramowicz, D, Claas, FHJ, Daniëls, L, Edmonds, MP, Hellemans, R, Kramer, CSM, Naessens, M, Senev, A, Van Laecke, Steven, Vanden Driessche, M   +9 more
core   +2 more sources

Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]

, 2003
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike, Engelmann, Bernd, Klocke, Antje, Kotzsch, Matthias, Luther, Thomas, Morgenstern, Eberhard, Müller, Ingrid, Preissner, Klaus, Zahler, Stefan, Zieseniss, Susanne   +9 more
core   +1 more source

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility. [PDF]

, 2011
BackgroundCell migration plays an important role in many physiological and pathological processes, including immune cell chemotaxis and cancer metastasis.
Liao, Kan, Liu, Yang, Wang, Wenqi
core   +2 more sources

Low disease activity of microscopic polyangiitis in patients with anti-myosin light chain 6 antibody that disrupts actin rearrangement necessary for neutrophil extracellular trap formation

Arthritis Research & Therapy, 2022
Background Neutrophil extracellular traps (NETs) are critically involved in microscopic polyangiitis (MPA) pathogenesis, and some patients with MPA possess anti-NET antibody (ANETA). Anti-myosin light chain 6 (MYL6) antibody is an ANETA that affects NETs.
Miku Yoshinari, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Utano Tomaru, Yoshihiro Arimura, Koichi Amano, Yukio Yuzawa, Ken-Ei Sada, Tatsuya Atsumi, Hiroaki Dobashi, Hitoshi Hasegawa, Masayoshi Harigai, Seiichi Matsuo, Hirofumi Makino, Akihiro Ishizu   +15 more
doaj   +1 more source

PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]

, 2007
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Adamson, Barreiro, Barreiro, Butcher, Carman, Carman, Carson, Celli, Christine Rampon, Cicmil, Doulet, Durieu-Trautmann, Engelhardt, Etienne, Etienne, Etienne-Manneville, Federici, Gopalakrishnan, Graesser, Gratzinger, Greenwood, Greenwood, Henshall, Hoffmann, Ilan, Jackson, Jean-Pierre Couty, John Greenwood, Kontaridis, Lacalle, Marie-Pierre Laran-Chich, Masuda, Mathilde Leveque, Millan, Muller, Newman, Newman, Patil, Pierre-Olivier Couraud, Pluskota, Reid, Rivard, Roux, Sander, Sandrine Bourdoulous, Schenkel, Schoenwaelder, Schweitzer, Shaw, Viegas, Walters, Wang, Yang, Yang   +53 more
core   +2 more sources

THE ANTIBODY-FORMATION BY POLYSACCHARIDS [PDF]

Journal of Experimental Medicine, 1929
1. By complement fixation tests, it has been clearly demonstrated that the sera of rabbits immunized with inulin, soluble starch and dextrine contain specific antibodies. 2. All these immune sera gave a negative precipitation reaction. 3.
openaire   +3 more sources

ANTIBODY FORMATION IN VITRO [PDF]

The Journal of Experimental Medicine, 1961
Neutralizing activity against T2 bacteriophage appeared in cultures of lymph node cells from normal rats in response to their in vitro stimulation with a cell-free filtrate derived from homogenized rat macrophages which had been incubated with T2 bacteriophage. This activity was specifically directed against T2 bacteriophage.
openaire   +3 more sources

Predicted Indirectly Recognizable HLA Epitopes Presented by HLA‐DRB1 Are Related to HLA Antibody Formation During Pregnancy

American Journal of Transplantation, 2015
Pregnancy can prime maternal immune responses against inherited paternal HLA of the fetus, leading to the production of child‐specific HLA antibodies. We previously demonstrated that donor‐specific HLA antibody formation after kidney transplantation is ...
K. Geneugelijk, G. Hönger, H. V. Deutekom, K. Thus, C. Keşmir, I. Hösli, S. Schaub, E. Spierings   +7 more
semanticscholar   +1 more source