Results 1 to 10 of about 849,234 (288)

Antibody Watch: Text mining antibody specificity from the literature. [PDF]

PLoS Computational Biology, 2021
Antibodies are widely used reagents to test for expression of proteins and other antigens. However, they might not always reliably produce results when they do not specifically bind to the target proteins that their providers designed them for, leading ...
Chun-Nan Hsu, Chia-Hui Chang, Thamolwan Poopradubsil, Amanda Lo, Karen A William, Ko-Wei Lin, Anita Bandrowski, Ibrahim Burak Ozyurt, Jeffrey S Grethe, Maryann E Martone   +9 more
doaj   +3 more sources

The Quest for Anti-α-Synuclein Antibody Specificity—Lessons Learnt From Flow Cytometry Analysis [PDF]

Frontiers in Neurology, 2022
The accumulation of alpha-synuclein (aSyn) is the hallmark of a group of neurodegenerative conditions termed synucleopathies. Physiological functions of aSyn, including those outside of the CNS, remain elusive.
Lukas Leupold, Veronika Sigutova, Elizaveta Gerasimova, Martin Regensburger, Martin Regensburger, Sebastian Zundler, Friederike Zunke, Wei Xiang, Beate Winner, Iryna Prots   +9 more
doaj   +2 more sources

Limited antibody specificity compromises epitranscriptomic analyses [PDF]

Nature Communications, 2019
A controversial discussion on the occurrence of the RNA modification m1A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.
Mark Helm, Frank Lyko, Yuri Motorin
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Antibody Specificity Following a Recent Bordetella pertussis Infection in Adolescence Is Correlated With the Pertussis Vaccine Received in Childhood [PDF]

Frontiers in Immunology, 2019
Bordetella (B.) pertussis resurgence affects not only the unvaccinated, but also the vaccinated population. Different vaccines are available, however, it is currently unknown whether the type of childhood vaccination has an influence on antibody ...
René H. M. Raeven, Larissa van der Maas, Jeroen L. A. Pennings, Kurt Fuursted, Charlotte Sværke Jørgensen, Elly van Riet, Bernard Metz, Gideon F. A. Kersten, Gideon F. A. Kersten, Tine Dalby   +9 more
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Novel protocol for selection of SARS-CoV2 convalenscent plasma donors [PDF]

Vojnosanitetski Pregled, 2022
Background/Aim. Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) 2019 infection represents a global problem. At this moment, in October 2020, there is no vaccine or efficient treatment for infected patients.
Ostojić Gordana, Šupić Gordana, Karličić Vukoica, Karličić Marija, Ristanović Elizabeta, Kovačević Milan, Abazović Džihan, Gojkov Dragana, Stanojević Ivan, Vukosavljević Miroslav, Vojvodić Danilo   +10 more
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Alternative Hapten Design for Zearalenone Immunoreagent Generation

Toxins, 2022
Appropriate hapten design and synthesis have been identified as critical steps to generate high-performance immunoreagents and to develop sensitive and selective immunoanalytical methods.
Antonio Abad-Fuentes, Consuelo Agulló, Daniel López-Puertollano, Ismael Navarro-Fuertes, Antonio Abad-Somovilla, Josep Vicent Mercader   +5 more
doaj   +1 more source

A strong case for third-party testing

eLife, 2023
A strategy to identify high-quality commercially available antibodies for research reveals extensive use of non-specific antibodies and offers solutions for future large-scale testing.
Fridtjof Lund-Johansen
doaj   +1 more source

Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain?

Biomolecules, 2020
Alpha7 nicotinic acetylcholine receptors (α7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [αBGT] binding ...
Anish Deshpande, Remitha M. Vinayakamoorthy, Brijesh K. Garg, Jaya Prakash Thummapudi, Gauri Oza, Ketaki Adhikari, Aayush Agarwal, Parnika Dalvi, Swetha Iyer, Sarulatha Thulasi Raman, Vijay Ramesh, Akshitha Rameshbabu, Alexandra Rezvaya, Sneha Sukumaran, Sweta Swaminathan, Bhargav Tilak, Zhiyuan Wang, Phu V. Tran, Ralph H. Loring   +18 more
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Frequency of alloantibody with their specification among multitransfused patients

Global Journal of Transfusion Medicine, 2020
Background and Objectives: Alloimmunization is a very common clinical problem in transfusion-dependent patients but rarely detected in Bangladesh.
Ayesha Khatun, Munshi Md Habibullah, Daanish Arefin Biswas, Md Abdul Quader, Jolly Biswas   +4 more
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Neoglycoconjugate of Tetrasaccharide Representing One Repeating Unit of the Streptococcus pneumoniae Type 14 Capsular Polysaccharide Induces the Production of Opsonizing IgG1 Antibodies and Possesses the Highest Protective Activity As Compared to Hexa- and Octasaccharide Conjugates

Frontiers in Immunology, 2017
Identifying protective synthetic oligosaccharide (OS) epitopes of Streptococcus pneumoniae capsular polysaccharides (CPs) is an indispensable step in the development of third-generation carbohydrate pneumococcal vaccines.
Ekaterina A. Kurbatova, Nelli K. Akhmatova, Elina A. Akhmatova, Nadezhda B. Egorova, Natalya E. Yastrebova, Elena V. Sukhova, Dmitriy V. Yashunsky, Yury E. Tsvetkov, Marina L. Gening, Nikolay E. Nifantiev   +9 more
doaj   +1 more source