Results 101 to 110 of about 9,814,118 (327)
PLoS ONE, 2019 The commercially available D-dimer assays used in the clinical practice often show differences in the results, and their specificity and sensitivity are rather unsatisfactory. Our aim was to develop a new monoclonal antibody against D-dimer with a proper
Beáta Török-Nagy +2 more
doaj +1 more source
The purification of azoprotein antibodies by the dissociation of specific precipitates [PDF]
, 1947 Felix Haurowitz +3 more
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
INCIDENCE AND SPECIFICITY OF THE ANTIBODY FOR A DISTINCTIVE CONSTITUENT OF THE BROWN-PEARCE TUMOR [PDF]
, 1945 I.Z. MacKenzie, John G. Kidd
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A Procedure Which Eliminates Nonspecific Inhibitor from Human Serum But does not Affect Specific Antibodies Against Influenza Viruses [PDF]
, 1952 D. A. J. Tyrrell, Frank L. Horsfall
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Structural Basis for Rabbit Hemorrhagic Disease Virus Antibody Specificity. [PDF]
J Virol, 2022 Leuthold MM +6 more
europepmc +1 more source
QUANTITATIVE EXPERIMENTS WITH ANTIBODIES TO SPECIFIC PRECIPITATES. II [PDF]
, 1941 Henry P. Treffers, Michael Heidelberger
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source