Results 11 to 20 of about 656,519 (242)

Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain?

Biomolecules, 2020
Alpha7 nicotinic acetylcholine receptors (α7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [αBGT] binding ...
Anish Deshpande, Remitha M. Vinayakamoorthy, Brijesh K. Garg, Jaya Prakash Thummapudi, Gauri Oza, Ketaki Adhikari, Aayush Agarwal, Parnika Dalvi, Swetha Iyer, Sarulatha Thulasi Raman, Vijay Ramesh, Akshitha Rameshbabu, Alexandra Rezvaya, Sneha Sukumaran, Sweta Swaminathan, Bhargav Tilak, Zhiyuan Wang, Phu V. Tran, Ralph H. Loring   +18 more
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Frequency of alloantibody with their specification among multitransfused patients

Global Journal of Transfusion Medicine, 2020
Background and Objectives: Alloimmunization is a very common clinical problem in transfusion-dependent patients but rarely detected in Bangladesh.
Ayesha Khatun, Munshi Md Habibullah, Daanish Arefin Biswas, Md Abdul Quader, Jolly Biswas   +4 more
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Specificity and application of SOX2 antibody

Poultry Science, 2020
Sox2 is known to play an important role in maintaining the totipotency and self-renewal of embryonic stem cells. The purpose of this study was to prepare an anti-chicken Sox2 polyclonal antibody using prokaryotic expression techniques, to evaluate its ...
Longqin Wei, Lixia Wang, Jianhong Pan, Lingkang Liu, Pengxia Wang, Jinyu Wei, Xiaoming Xu, Qingbo Xing, Ping Liu, Wende Wu, Gonghe Li, Xibang Zheng   +11 more
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IgG Study of Blood Sera of Patients with COVID-19

Pathogens, 2021
The COVID-19 pandemic, which began at the end of 2019 in Wuhan, has affected 220 countries and territories to date. In the present study, we studied humoral immunity in samples of the blood sera of COVID-19 convalescents of varying severity and patients ...
Elena Kazachinskaia, Alexander Chepurnov, Dmitry Shcherbakov, Yulia Kononova, Teresa Saroyan, Marina Gulyaeva, Daniil Shanshin, Valeriya Romanova, Olga Khripko, Michail Voevoda, Alexander Shestopalov   +10 more
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Neoglycoconjugate of Tetrasaccharide Representing One Repeating Unit of the Streptococcus pneumoniae Type 14 Capsular Polysaccharide Induces the Production of Opsonizing IgG1 Antibodies and Possesses the Highest Protective Activity As Compared to Hexa- and Octasaccharide Conjugates

Frontiers in Immunology, 2017
Identifying protective synthetic oligosaccharide (OS) epitopes of Streptococcus pneumoniae capsular polysaccharides (CPs) is an indispensable step in the development of third-generation carbohydrate pneumococcal vaccines.
Ekaterina A. Kurbatova, Nelli K. Akhmatova, Elina A. Akhmatova, Nadezhda B. Egorova, Natalya E. Yastrebova, Elena V. Sukhova, Dmitriy V. Yashunsky, Yury E. Tsvetkov, Marina L. Gening, Nikolay E. Nifantiev   +9 more
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IgM Antibodies Can Access Cryptic Antigens Denied to IgG: Hypothesis on Novel Binding Mechanism

Frontiers in Immunology, 2019
Antibodies are well-known protein mediators of immunity. IgM is the primordial member and the neglected sibling of the later-evolved and more proficient IgG in regard to their therapeutic and diagnostic use.
Eric Chun Yiu Law, Danny Tze Ming Leung, Frankie Chi Hang Tam, Frankie Chi Hang Tam, Kitty Kit Ting Cheung, Naomi Hua Yin Cheng, Pak Leong Lim, Pak Leong Lim   +7 more
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Factors affecting the efficacy of platelet transfusion and specificity of HLA-Ⅰ antibodies in tumor patients

Zhongguo shuxue zazhi, 2023
Objective To analyze the factors affecting the efficacy of platelet transfusion and the specificity of HLA-Ⅰ antibodies in tumor patients. Methods Tumer patients applied for platelet transfusion from November 2019 to July 2021 in Sichuan Cancer Hospital ...
Juan SAI, Shanshan WAN, Li TIAN
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Cautionary notes on the use of NF-κB p65 and p50 antibodies for CNS studies

Journal of Neuroinflammation, 2011
Background The characterization and cellular localization of transcription factors like NF-κB requires the use of antibodies for western blots and immunohistochemistry.
Listwak Samuel J, Brown Pierre, Rathore Priyanka, Herkenham Miles   +3 more
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Machine Learning to Quantify In Situ Humoral Selection in Human Lupus Tubulointerstitial Inflammation

Frontiers in Immunology, 2020
In human lupus nephritis, tubulointerstitial inflammation (TII) is associated with in situ expansion of B cells expressing anti-vimentin antibodies (AVAs). The mechanism by which AVAs are selected is unclear.
Andrew J. Kinloch, Yuta Asano, Azam Mohsin, Carole Henry, Rebecca Abraham, Anthony Chang, Christine Labno, Patrick C. Wilson, Marcus R. Clark   +8 more
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Biochemical patterns of antibody polyreactivity revealed through a bioinformatics-based analysis of CDR loops

eLife, 2020
Antibodies are critical components of adaptive immunity, binding with high affinity to pathogenic epitopes. Antibodies undergo rigorous selection to achieve this high affinity, yet some maintain an additional basal level of low affinity, broad reactivity
Christopher T Boughter, Marta T Borowska, Jenna J Guthmiller, Albert Bendelac, Patrick C Wilson, Benoit Roux, Erin J Adams   +6 more
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