Results 21 to 30 of about 971,999 (350)

IgM Antibodies Can Access Cryptic Antigens Denied to IgG: Hypothesis on Novel Binding Mechanism

open access: yesFrontiers in Immunology, 2019
Antibodies are well-known protein mediators of immunity. IgM is the primordial member and the neglected sibling of the later-evolved and more proficient IgG in regard to their therapeutic and diagnostic use.
Eric Chun Yiu Law   +7 more
doaj   +1 more source

Biochemical patterns of antibody polyreactivity revealed through a bioinformatics-based analysis of CDR loops

open access: yeseLife, 2020
Antibodies are critical components of adaptive immunity, binding with high affinity to pathogenic epitopes. Antibodies undergo rigorous selection to achieve this high affinity, yet some maintain an additional basal level of low affinity, broad reactivity
Christopher T Boughter   +6 more
doaj   +1 more source

Preclinical Analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and In Vivo Imaging. [PDF]

open access: yes, 2018
The tumor specificity of JAA-F11, a novel monoclonal antibody specific for the Thomsen-Friedenreich cancer antigen (TF-Ag-alpha linked), has been comprehensively studied by in vitro immunohistochemical (IHC) staining of human tumor and normal tissue ...
Adams, Julia   +13 more
core   +2 more sources

Development and validation of an ELISA to detect antibodies to Corynebacterium pseudotuberculosis in ovine sera [PDF]

open access: yes, 2007
Several enzyme-linked immunosorbent assays (ELISAs) have been developed for the detection of antibodies to Corynebacterium pseudotuberculosis, the causative agent of caseous lymphadenitis (CLA). However, none are commercially available in the UK.
Bailey, Mick   +2 more
core   +4 more sources

Neoglycoconjugate of Tetrasaccharide Representing One Repeating Unit of the Streptococcus pneumoniae Type 14 Capsular Polysaccharide Induces the Production of Opsonizing IgG1 Antibodies and Possesses the Highest Protective Activity As Compared to Hexa- and Octasaccharide Conjugates

open access: yesFrontiers in Immunology, 2017
Identifying protective synthetic oligosaccharide (OS) epitopes of Streptococcus pneumoniae capsular polysaccharides (CPs) is an indispensable step in the development of third-generation carbohydrate pneumococcal vaccines.
Ekaterina A. Kurbatova   +9 more
doaj   +1 more source

Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. [PDF]

open access: yes, 2017
Surface enhanced Raman scattering (SERS) nanoparticles are an attractive alternative to fluorescent probes for biological labeling because of their photostability and multiplexing capabilities.
Candas, Demet   +7 more
core   +1 more source

Hybrid cell lines producing monoclonal antibodies directed against Treponema [PDF]

open access: yes, 1985
Continuous hybrid cell lines for producing monoclonal antibodies directed against antigens of Treponema pallidum have been developed. The hybrid cell lines were established by fusing differentiated lymphoid cells primed with antigens of Treponema ...
Kettman, John R., Norgard, Michael V.
core   +1 more source

Machine Learning to Quantify In Situ Humoral Selection in Human Lupus Tubulointerstitial Inflammation

open access: yesFrontiers in Immunology, 2020
In human lupus nephritis, tubulointerstitial inflammation (TII) is associated with in situ expansion of B cells expressing anti-vimentin antibodies (AVAs). The mechanism by which AVAs are selected is unclear.
Andrew J. Kinloch   +8 more
doaj   +1 more source

Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]

open access: yes, 2014
Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Griffiths, Gareth, Lucocq, John Milton
core   +1 more source

Antibodies to guanosine [PDF]

open access: yesFEBS Letters, 1984
Bovine serum albumin conjugates of guanosine prepared by the periodate method was used as immunogen to elicit guanosine antibodies in rabbits. The specificities of the antibodies were studied by the inhibition of their binding to [3H]Gox‐red, [32P]DNA and [3H]RNA by related non‐radioactive compounds.
Iswari, S, Jacob, TM
openaire   +3 more sources

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