Results 121 to 130 of about 417,719 (249)

Photochemical Synthesis of Polycyclic Phosphonium Salts as Efficient Anticancer and Antibacterial Agents [PDF]

Jianqing Li, Zeyan Zhuang, Xiaobin Dong, Zujin Zhao, Ben Zhong Tang   +4 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Ab initio studies of single-wall carbon nanotube for drug delivery of (N- acetyl-L-cysteinato-O, S) diphenyl tin (IV) anticancer drug

, 2012
Amir Sobhanmanesh
openalex   +1 more source

EMULSOMES FOR LIPOPHILIC ANTICANCER DRUG DELIVERY: DEVELOPMENT, OPTIMIZATION AND IN VITRO DRUG RELEASE KINETIC STUDY

, 2021
Swati Dubey, Suresh P. Vyas
openalex   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Correction: Bioproduction, characterization, anticancer and antioxidant activities of extracellular melanin pigment produced by newly isolated microbial cell factories Streptomyces glaucescens NEAE-H. [PDF]

Sci Rep
El-Naggar NE, El-Ewasy SM.
europepmc   +1 more source

IN VITRO ANTICANCER EFFECT OF ARTABOTRYS CRASSIFOLIUS HOOK.F. & THOMSON AGAINST HUMAN CARCINOMA CELL LINES

, 2014
Kok Kwan Tan, Tracey D. Bradshaw, Jessica Chu, Teng-Jin Khoo, Christophe Wiart   +4 more
openalex   +2 more sources

Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death–Ligand 1 Interaction as Potential Anticancer Agents

, 2020
Binbin Cheng, Yichang Ren, Xiaoge Niu, Wei Wang, Shuanghu Wang, Yingfeng Tu, Shuwen Liu, Jin Wang, Deying Yang, Guochao Liao, Jianjun Chen   +10 more
openalex   +1 more source

Enhancement of anticancer activity by silibinin and paclitaxel combination on the ovarian cancer [PDF]

, 2017
Fatima Pashaei-Asl, Roghiyeh Pashaei‐Asl, Khodadad Khodadadi, Abolfazl Akbarzadeh, Esmaeil Ebrahimie, Maryam Pashaiasl   +5 more
openalex   +1 more source