Results 91 to 100 of about 333,871 (264)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Purification, Characterization and Anticancer Activity of L-asparaginase Produced by Marine Aspergillus terreus

open access: yes, 2018
L-asparaginase (E.C.3.5.1.1) is an enzyme responsible for hydrolysis of L-asparagine into aspartic acid and ammonia, and has its significant applications in the therapeutics and food technology.
Sahar W.M. Hassan   +2 more
core   +1 more source

Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands [PDF]

open access: yes, 2011
Organometallic IrIII cyclopentadienyl complexes [(η5-Cpx)Ir(CN)Cl] {Cpx = Cp*, CN = 2-(p-tolyl)pyridine (1), 2-phenylquinoline (2), 2-(2,4-difluorophenyl)pyridine (3), Cpx = tetramethyl(phenyl)cyclopentadienyl (Cpxph), CN = 2-phenylpyridine (4), and Cpx =
Liu, Zhe   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma

open access: yes, 2015
Tae Won Kwak,1,* Hee Jae Shin,2,* Young-Il Jeong,1 Myoung-Eun Han,3 Sae-Ock Oh,3 Hyun-Jung Kim,4 Do Hyung Kim,5 Dae Hwan Kang1 1Biomedical Research Institute, Pusan National University Hospital, Busan, 2Marine Natural Products Chemistry Laboratory ...
Jeong YI   +7 more
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Azatyrosinamides: Novel RAS-related anticancer agents

open access: yes, 2013
[[abstract]]Background: We previously reported on the design and synthesis of novel azatyrosinamide derivatives selective for ras-transformed NIH3T3 cells and with improved toxicity over azatyrosine. This study was aimed at investigating the mechanism of
Wang, CL;Lee, O;Huang, CF;Li, EIC;Teng, CM;Pan, SL;Lian, JF;Chang, FS;Liou, JP;Wang, HP
core  

Bioactivity of Edible Mushroom Agaricus Campestris [PDF]

open access: yes, 2017
Here we determined antioxidant, antimicrobial and anticancer properties of edible mushroom Agaricus campestris. Antioxidant activity was evaluated by free radical scavenging, superoxide anion scavenging and reducing power. A.
Kosanic, Marijana   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells

open access: yes, 2015
Katarzyna Niemirowicz,1 Izabela Prokop,2 Agnieszka Z Wilczewska,3 Urszula Wnorowska,1 Ewelina Piktel,1 Marzena Wątek,4 Paul B Savage,5 Robert Bucki1,6 1Department of Microbiological and Nanobiomedical Engineering, Medical University of Bialystok ...
Bucki R   +7 more
core  

Home - About - Disclaimer - Privacy