Results 101 to 110 of about 333,871 (264)

CYTOTOXICITY AND ANTICARCINOGENIC ACTIVITY OF TWO FLAVONOIDS ISOLATED AND PURIFIED FROM Brownea ariza Brenth

Vitae, 2009
The growing resistance to anticancer agents has turned medical science and pharmacology towards finding new compounds with these characteristics; in this area the natural products have great relevance, since many of these have anticancer activity ...
Juan F. GIL R., Milton GÓMEZ B., Juanita TREJOS S.   +2 more
doaj  

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Quinoxaline chemistry. Part 8. 2-[anilino]-3- [carboxy]-6(7)-substituted quinoxalines as non classical antifolate agents. Synthesis and evaluation of in vitro anticancer, anti-HIV and antifungal activity

, 1997
Thirty quinoxalines bearing a substituted anilino group on position 2, a carboethoxy or carboxy group on position 3 and a trifluoromethyl group on position 6 or 7 of the heterocycle were prepared in order to evaluate in vitro anticancer activity ...
Paglietti, Giuseppe, Zanetti, Stefania Anna Lucia, Loriga, Mario, Moro, Pierangelo   +3 more
core  

Anticancer Activity of Andrographolide Semisynthetic Derivatives

Natural Product Communications, 2010
Andrographolide 1 , a diterpene lactone of Andrographis paniculata , displays in vitro and in vivo antitumor activity against breast cancer models and mouse myeloid leukemia (M1) cells.
Vidya Menon, Sujata Bhat
doaj   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Evaluating Medicinal Plants for Anticancer Activity

The Scientific World Journal, 2014
Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives.
Elisha Solowey, Michal Lichtenstein, Sarah Sallon, Helena Paavilainen, Elaine Solowey, Haya Lorberboum-Galski   +5 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Anticancer activity of biostabilized selenium nanorods synthesized by Streptomyces bikiniensis strain Ess_amA-1

, 2015
Maged Sayed Ahmad,1 Manal Mohamed Yasser,1 Essam Nageh Sholkamy,1,2 Ali Mohamed Ali,3,4 Magda Mohamed Mehanni3 1Department of Botany, Faculty of Science, University of Beni-Suef, Beni-Suef, Egypt; 2Department of Botany and Microbiology, College of ...
Yasser MM, Ali AM, Ahmad MS, Mehanni MM, Sholkamy EN   +4 more
core  

Bioactive Composition, Antioxidant Activity, and Anticancer Potential of Freeze-Dried Extracts from Defatted Gac (Momordica cochinchinensis Spreng) Seeds

, 2018
Background: Gac (Momordica cochinchinensis Spreng) seeds have long been used in traditional medicine as a remedy for numerous conditions due to a range of bioactive compounds.
Sophie E. Parks, Sophie E. Parks, Minh H. Nguyen, Paul D. Roach, Anh V. Le, Nguyen, Minh H. (R8307), Minh H. Nguyen, Roach, Paul D., Huynh, Tien T., Parks, Sophie E., Paul D. Roach, Tien T. Huynh, Le, Anh V., Anh V. Le, Tien T. Huynh   +14 more
core   +1 more source

Near‐Infrared Light‐Driven Zn/Au Janus Micromotors for Multiplex SERS Detection of Anticancer Drugs

Advanced Functional Materials, EarlyView.
Zn/Au Janus micromotors, propelled by thermophoretic effects under NIR light, function as active SERS platforms for single and multiplex detection of anticancer drugs. Their dynamic motion enhances analyte exchange at the Au interface, reducing saturation and competitive adsorption, thereby improving sensitivity and extending the linear detection range.
Tijana Maric, Gohar Soufi, Ziqiao Li, Erick Chica, Amran Abdirasheed Ali Jinow, Nada Al‐Roubaï, Noor Ahmed, Yaman Göksel, Anja Boisen   +8 more
wiley   +1 more source