Results 121 to 130 of about 333,871 (264)
, 2011 Withanolides are a group of natural C-28 steroids built on an ergostane skeleton and classified into two major groups according to their structural skeleton: (a) compounds with a beta-oriented side chain and (b) compounds with an alpha-oriented side ...
Feroz Khan, Om Prakash, R.S. Sangwan
core +1 more source
Synthesis, Structure, and In Vitro Biological Evaluation of Semi-Synthetic Derivatives of Betulin
Applied SciencesBetulin and α-lipoic acid are naturally occurring substances with different biological properties. Combining two phytochemical units into a conjugate is a frequently used method to obtain new compounds with better pharmacokinetic parameters.
Elwira Chrobak +3 more
doaj +1 more source
Ultra‐High‐Throughput Discovery of Multifunctional Polyphenolic Coatings on Droplet Microarrays
Advanced Materials, EarlyView.An ultra‐high‐throughput (UHT) combinatorial strategy enables the miniaturized synthesis and screening of ≈30 000 polyamine‐polyphenolic (PaPp) coatings using droplet microarrays (DMA). This approach reveals hundreds of previously unknown fluorescent, redox‐active, and antibacterial materials, including multifunctional, cell‐compatible surfaces ...
Vania Tanda Widyaya +11 more
wiley +1 more source
Induction of Epstein-Barr virus (EBV) reactivation in Raji cells by doxorubicin and cisplatin
, 2008 [[abstract]]Background: Epstein-Barr virus (EBV) can be activated in B-lymphoid cells to enter the lytic cycle by various kinds of stimuli, including 12-O-tetradecanoylphorbol-1 3-acetate (TPA), butytic acid, calcium ionophore A23187, transforming growth
Hsu, CH; Hergenhahn, M; Chuang, SE; Yeh, PY; Wu, TC; Gao, M; Cheng, AL
core
Colorectal cancer is one of the most prevalent malignancies worldwide and a leading cause of mortality. Chemotherapy medications are often limited in use due to issues like drug resistance, P-glycoprotein efflux, and relapse of chemotherapy.
Arumugam Madeswaran +2 more
core +1 more source
Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review
Advanced Robotics Research, EarlyView.Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley +1 more source
Telomere-targeting anticancer drugs
, 2011 In normal somatic cells, telomere length decreases with each replication event, until a critical state of replicative senescence is reached. On the contrary, telomere maintenance is evident in all types of cancer cells.
PAGANO, BRUNO
core
SINTEZA UNOR TIOSEMICARBAZONE ÎN BAZA N-{4-[(HIDRAZINILCARBONOTIOIL)AMINO]FENIL}ACETAMIDEI
Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2017 În articol sunt descrise metodele de sinteză a șase compuși organici, dintre care trei nu sunt cunoscuți în literatura de specialitate. Structura compușilor a fost determinată cu ajutorul spectroscopiei: RMN 1H,13C și IR.
Roman RUSNAC +4 more
doaj
Advanced Robotics Research, EarlyView.An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles
, 2004 The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Dufès, Christine +5 more
core +1 more source