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Frontiers in Chemistry, 2022 Natural coumarin derivatives and cyclometallic iridium (Ⅲ) (IrⅢ) complexes have attracted much attention in the field of anticancer. In this study, six coumarin-modified cyclometallic IrⅢ salicylaldehyde Schiff base complexes ([(ppy)2Ir(O^N)]/[(ppy-CHO ...
Ruixi Xu +4 more
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PIM KINASES INHIBITORS AND PYRIMIDINE-BASED ANTICANCER AGENTS [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2023 Human phosphatidyl inositol mannoside kinases (Pim kinases) are important biological target for discovery of new anticancer agents. In addition, Pyrimidines have a good contribution as building blocks of many anticancer agents. Hence, a literature survey
ibrahim issa +3 more
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Monofunctional Platinum(II) Anticancer Agents
Pharmaceuticals, 2021 Platinum-based anticancer drugs represented by cisplatin play important roles in the treatment of various solid tumors. However, their applications are largely compromised by drug resistance and side effects.
Suxing Jin +3 more
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Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents [PDF]
Kidney Research and Clinical Practice, 2021 Kidney injury caused by anticancer agents is a common problem that can interfere with and affect the dose intensity of anticancer therapy, thus restricting patient survival.
Min Hee Hong
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Using Chitosan or Chitosan Derivatives in Cancer Therapy
Polysaccharides, 2021 Cancer is one of the major causes of death worldwide. Chemotherapeutic drugs have become a popular choice as anticancer agents. Despite the therapeutic benefits of chemotherapeutic drugs, patients often experience side effects and drug resistance ...
Md Salman Shakil +7 more
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[(η5-pentamethylcyclopentadienyl)(3-fluoro-N-methylbenzylamine-к1,N)dichlorido]iridium(III)
Molbank, 2018 A half-sandwich iridium(III) complex containing 3-fluoro-N-methylbenzylamine ligands has been obtained by reaction of one equivalent of [(η5-Cp*)IrCl2]2 (Cp* = pentamethylcyclopentadienyl) with two equivalent of 3-fluoro-N-methylbenzylamine in very ...
Deliang Kong +4 more
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Perspectives in Clinical Research, 2022 Aims/Objectives: This study was conducted to assess the utilization patterns of anticancer agents in patients with breast cancer and to provide practice recommendations/educational interventions to optimize medication use in patients with breast cancer ...
Aakanksha Sharma +2 more
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Kinase Targeted Anticancer Agents: A Perspective
NUST Journal of Natural Sciences, 2022 The phosphate group present in the ATP (adenosine triphosphate) is transferred to the hydroxy group-containing tyrosine, serine, or threonine residue by the protein kinases encoded in the human genome. Till now, a large number of these kinases have been
Shannelle Diana Habániková +2 more
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Vanadium Complexes as Potential Anticancer Agents
Engineering Proceedings, 2023 For the structure and functioning of bio-molecules, metals are important. The main focus of research remains the design and synthesis of novel metal-based complexes and metal ion binding to substances in search of novel medicines.
Satya +4 more
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Marine Natural Products as Anticancer Agents
Marine Drugs, 2021 Cancer remains one of the major threats to human health and one of the deadliest diseases worldwide [...]
Celso Alves, Marc Diederich
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