Results 11 to 20 of about 241,274 (262)
Benzothiazole derivatives as anticancer agents
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Benzothiazole (BTA) belongs to the heterocyclic class of bicyclic compounds. BTA derivatives possesses broad spectrum biological activities such as anticancer, antioxidant, anti-inflammatory, anti-tumour, antiviral, antibacterial, anti-proliferative ...
Ali Irfan +7 more
doaj +2 more sources
Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agents
Biologics: Targets & Therapy, 2013 Katherine Ververis,1 Alison Hiong,1 Tom C Karagiannis,1,* Paul V Licciardi2,*1Epigenomic Medicine, Alfred Medical Research and Education Precinct, 2Allergy and Immune Disorders, Murdoch Childrens Research Institute, Melbourne, VIC, Australia*These ...
Ververis K +3 more
doaj +2 more sources
Bis-Oxadiazole Assemblies as NO-Releasing Anticancer Agents [PDF]
PharmaceuticsBackground: Malignant pleural mesothelioma (MPM) is an aggressive, asbestos-associated cancer characterized by dysregulated nitric oxide (NO) signaling and increased NO levels that facilitate tumor progression. Paradoxically, this aberrant NO environment
Egor M. Matnurov +7 more
doaj +2 more sources
Anticancer agents from medicinal plants
Bangladesh Journal of Pharmacology, 2006 Cancer is a major public health burden in both developed and developing countries. Plant derived agents are being used for the treatment of cancer.
Mohammad Shoeb
doaj +1 more source
, 2021 This book is a printed edition of the Special Issue entitled “Anticancer Agents: Design, Synthesis and Evaluation” that was published in Molecules. Two review articles and thirty research papers are included in the Special Issue.
core +2 more sources
Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]
, 2009 This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Rijt, Sabine H. van, Sadler, P. J.
core +1 more source
SGLT2 Inhibitors as Potential Anticancer Agents
Biomedicines, 2023 Sodium-glucose cotransporter 2 (SGLT2) serves as a critical glucose transporter that has been reported to be overexpressed in cancer models, followed by increased glucose uptake in both mice and humans.
Debasish Basak, David Gamez, Subrata Deb
doaj +1 more source
Plant-derived anticancer agents: A green anticancer approach
Asian Pacific Journal of Tropical Biomedicine, 2017 Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure. Plants are reservoirs for novel chemical entities and provide a promising line for research on cancer ...
Javed Iqbal +6 more
doaj +1 more source
Unusual DNA binding modes for metal anticancer complexes [PDF]
, 2009 DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core +1 more source
Nature Communications, 2017 Soluble misfolded proteins that fail to be degraded by the ubiquitin proteasome system (UPS) are redirected to autophagy via specific adaptors, such as p62.
Hyunjoo Cha-Molstad +25 more
doaj +1 more source