Results 1 to 10 of about 85,002 (346)

Recent developments on triazole nucleus in anticonvulsant compounds: a review

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
Epilepsy is one of the common diseases seriously threatening life and health of human. More than 50 million people are suffering from this condition and anticonvulsant agents are the main treatment.
Ming-Xia Song, Xian-Qing Deng
doaj   +2 more sources

Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects

open access: yesFrontiers in Cell and Developmental Biology, 2022
Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders.
John W. Steele   +13 more
doaj   +1 more source

Extract of Euterpe oleracea Martius Stone Presents Anticonvulsive Activity via the GABAA Receptor

open access: yesFrontiers in Cellular Neuroscience, 2022
Epilepsy is one of the most common neurological diseases globally, resulting from a disorder in brain activity. This condition can be triggered by birth trauma, traumatic brain injury (TBI), infections of the brain and stroke. More than 70 million people
Nilton Akio Muto   +6 more
doaj   +1 more source

Bone mineral density, vitamin D and anticonvulsant therapy [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2000
The aim of this study was to assess bone mineral density and vitamin D metabolism in patients on chronic anticonvulsant therapy. METHODS: Sixty-nine men, outpatients on chronic anticonvulsant therapy, who had been treated for at least 5 years, were ...
SILVANA FILARDI   +3 more
doaj   +1 more source

Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials [PDF]

open access: yesالمجلة العراقية للصيدلة, 2022
Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial, anticoagulant, antihypertensive, anticancer, antioxidant, anti ...
Rahma Jebir, Yasser Mustafa
doaj   +1 more source

Anticonvulsants in pregnancy. [PDF]

open access: yesArchives of Disease in Childhood, 1991
Epilepsy and pregnancy Recurrent seizures affect at least 1% of women who are of childbearing age, but as the fertility of both men and women with epilepsy is slightly reduced,' about one in 200 pregnancies occurs in a woman with epilepsy. Most of these women are taking anticonvulsants regularly.
Robert F W Moulds, Christine Kilpatrick
openaire   +6 more sources

Anticonvulsants for tinnitus [PDF]

open access: yesCochrane Database of Systematic Reviews, 2009
Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation. It is a common and potentially distressing symptom for which no adequate therapy exists.To assess the effectiveness of anticonvulsants in patients with chronic tinnitus.We searched the Cochrane Ear, Nose and Throat Disorders Group Specialised ...
Hoekstra, C.E.   +4 more
openaire   +6 more sources

Continuous rate infusion of midazolam as emergent treatment for seizures in dogs

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Midazolam delivered by continuous rate infusion (CRI) might be effective in dogs with cluster seizures (CS) or status epilepticus (SE). Objective To describe the use and safety of midazolam CRI in dogs with CS or SE.
Kathryn Y. Bray   +4 more
doaj   +1 more source

Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents

open access: yesScientia Pharmaceutica, 2020
Here, we describe the synthesis and anticonvulsant activity of thiazole-bearing hybrids based on 2-imino-4-thiazolidinone and 2,4-dioxothiazolidine-5-carboxylic acid cores.
M. Mishchenko   +3 more
semanticscholar   +1 more source

Preparation of Nanocrystals for Insoluble Drugs by Top-Down Nanotechnology with Improved Solubility and Bioavailability

open access: yesMolecules, 2020
Midazolam is a rapidly effective benzodiazepine drug that is widely used as a sedative worldwide. Due to its poor solubility in a neutral aqueous solution, the clinical use of midazolam is significantly limited.
Xun Zhang   +8 more
doaj   +1 more source

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