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Anticonvulsants in pregnancy. [PDF]
Archives of Disease in Childhood, 1991 Epilepsy and pregnancy Recurrent seizures affect at least 1% of women who are of childbearing age, but as the fertility of both men and women with epilepsy is slightly reduced,' about one in 200 pregnancies occurs in a woman with epilepsy. Most of these women are taking anticonvulsants regularly.
Robert F W Moulds, Christine Kilpatrick
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Anticonvulsants for tinnitus [PDF]
Cochrane Database of Systematic Reviews, 2009 Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation. It is a common and potentially distressing symptom for which no adequate therapy exists.To assess the effectiveness of anticonvulsants in patients with chronic tinnitus.We searched the Cochrane Ear, Nose and Throat Disorders Group Specialised ...
Hoekstra, C.E. +4 more
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Anticonvulsants for fibromyalgia [PDF]
Cochrane Database of Systematic Reviews, 2013 Fibromyalgia (FM) is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. People often report high disability levels and poor health-related quality of life (HRQoL). Drug therapy focuses on reducing key symptoms and disability, and improving HRQoL.
Nurcan Üçeyler +3 more
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Searching for New Leads to Treat Epilepsy: Target-Based Virtual Screening for the Discovery of Anticonvulsant Agents [PDF]
, 2018 The purpose of this investigation is to contribute to the development of new anticonvulsant drugs to treat patients with refractory epilepsy. We applied a virtual screening protocol that involved the search into molecular databases of new compounds and ...
Bruno Blanch, Luis Enrique +8 more
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Impaired biotin status in anticonvulsant therapy [PDF]
, 1982 In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher ...
Bonjour +7 more
core +1 more source
Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]
, 2014 Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
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Epilepsia Open, 2019 Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf +5 more
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Salvinorin A Does Not Affect Seizure Threshold in Mice
Molecules, 2020 The κ-opioid receptor has recently gained attention as a new molecular target in the treatment of many psychiatric and neurological disorders including epilepsy.
Katarzyna Socała +2 more
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Inhibitory Effect of Eslicarbazepine Acetate and S-Licarbazepine on Nav1.5 Channels
Frontiers in Pharmacology, 2020 Eslicarbazepine acetate (ESL) is a dibenzazepine anticonvulsant approved as adjunctive treatment for partial-onset epileptic seizures. Following first pass hydrolysis of ESL, S-licarbazepine (S-Lic) represents around 95% of circulating active metabolites.
Theresa K. Leslie +5 more
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Effect of different agonistic experiences on behavioural seizures in fully amygdala kindled rats [PDF]
, 1992 Fully amygdala kindled rats were exposed to two different inter-male agonistic experiences in order to study the interaction between epilepsy and acute social stress.
Beldhuis, Hans J.A., +2 more
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