Results 11 to 20 of about 131,323 (382)

Extract of Euterpe oleracea Martius Stone Presents Anticonvulsive Activity via the GABAA Receptor

open access: yesFrontiers in Cellular Neuroscience, 2022
Epilepsy is one of the most common neurological diseases globally, resulting from a disorder in brain activity. This condition can be triggered by birth trauma, traumatic brain injury (TBI), infections of the brain and stroke. More than 70 million people
Nilton Akio Muto   +6 more
doaj   +1 more source

Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen*

open access: yesJournal of Biological Chemistry, 2001
Valproic acid is widely used to treat epilepsy and bipolar disorder and is also a potent teratogen, but its mechanisms of action in any of these settings are unknown. We report that valproic acid activates Wntdependent gene expression, similar to lithium,
C. Phiel   +5 more
semanticscholar   +1 more source

Timing of Anticonvulsant Administration in Status Epilepticus

open access: yesPediatric Neurology Briefs, 2015
Investigators from the Pediatric Status Epilepticus Research Group studied the time elapsed from onset of pediatric convulsive status epilepticus (SE) to administration of antiepileptic drugs (AED).
Juan A Piantino
doaj   +1 more source

Bone mineral density, vitamin D and anticonvulsant therapy [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2000
The aim of this study was to assess bone mineral density and vitamin D metabolism in patients on chronic anticonvulsant therapy. METHODS: Sixty-nine men, outpatients on chronic anticonvulsant therapy, who had been treated for at least 5 years, were ...
SILVANA FILARDI   +3 more
doaj   +1 more source

Effect of different agonistic experiences on behavioural seizures in fully amygdala kindled rats [PDF]

open access: yes, 1992
Fully amygdala kindled rats were exposed to two different inter-male agonistic experiences in order to study the interaction between epilepsy and acute social stress.
Beldhuis, Hans J.A.,   +2 more
core   +2 more sources

Recognition Memory After Febrile Seizures

open access: yesPediatric Neurology Briefs, 2012
Researchers at the Institute of Child Health, London; Epilepsy Center, University of Edinburgh; and Dartmouth Medical School, New Hampshire, US studied memory abilities in 26 children (mean age 23 months, SD 12.6 months) after prolonged febrile seizures (
J Gordon Millichap
doaj   +1 more source

Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects

open access: yesFrontiers in Cell and Developmental Biology, 2022
Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders.
John W. Steele   +13 more
doaj   +1 more source

Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy

open access: yesBiomolecules, 2019
Epilepsy is a most disabling neurological disorder affecting all age groups. Among the various mechanisms that may result in epilepsy, neuronal hyperexcitability and oxidative injury produced by an excessive formation of free radicals may play a role in ...
Diogo Vilar da Fonsêca   +4 more
semanticscholar   +1 more source

Teratogenic risk and contraceptive counselling in psychiatric practice: analysis of anticonvulsant therapy [PDF]

open access: yes, 2013
<p>Background: Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require ...
A Basan   +23 more
core   +2 more sources

Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model

open access: yesEpilepsia Open, 2019
Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf   +5 more
doaj   +1 more source

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