Results 21 to 30 of about 128,593 (391)
Teratogenic risk and contraceptive counselling in psychiatric practice: analysis of anticonvulsant therapy [PDF]
, 2013 <p>Background: Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require ...
A Basan +23 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Histamine H3 receptors (H3R) antagonists/inverse agonists are becoming a promising therapeutic approach for epilepsy. In this article, novel nonimidazole H3R antagonists/inverse agonists have been designed and synthesised via hybriding the H3R ...
Mingxia Song +5 more
doaj +1 more source
Scientia Pharmaceutica, 2023 Mental and neurological disorders are conditions that affect thoughts, emotions, behavior, and relationships. Malpighia mexicana A. Juss. is a plant used in Mexican traditional medicine for the treatment of such disorders.
Dante Avilés-Montes +11 more
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Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy
Biomolecules, 2019 Epilepsy is a most disabling neurological disorder affecting all age groups. Among the various mechanisms that may result in epilepsy, neuronal hyperexcitability and oxidative injury produced by an excessive formation of free radicals may play a role in ...
Diogo Vilar da Fonsêca +4 more
semanticscholar +1 more source
Epilepsia Open, 2019 Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf +5 more
doaj +1 more source
Antiepileptic Drug Discovery and Development: What Have We Learned and Where Are We Going?
Pharmaceuticals, 2010 Current marketed antiepileptic drugs (AEDs) consist of a variety of structural classes with different mechanisms of action. These agents typically have non-overlapping efficacy and side-effect profiles presenting multiple treatment options for the ...
Jeffrey L. Krajewski, Aaron C. Gerlach
doaj +1 more source
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
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The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice
Molecules, 2019 Epilepsy is a prevalent neurological disorder that was reported to affect about 56 million people in the world. Approximately one-third of the epileptic patients that suffer from seizures do not receive effective medical treatment.
Xiao Zhang +8 more
doaj +1 more source
Antiepileptic drugs reduce serum uric acid [PDF]
, 1987 Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab +7 more
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Molecules, 2015 A novel series of benzenesulfonamide derivatives containing 4-aminobenzenesul-fonamide and α-amides branched valproic acid or 2,2-dimethylcyclopropanecarboxylic acid moieties were synthesized and screened for their anticonvulsant activities in mice ...
Zhiming Wang +5 more
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