Results 21 to 30 of about 131,323 (382)

Patient Harm Resulting From Medication Reconciliation Process Failures: A Study of Serious Events Reported by Pennsylvania Hospitals

open access: yesPatient Safety, 2021
Medication reconciliation broadly defined includes both formal and informal processes that involve the comprehensive evaluation of a patient’s medications during each transition of care and change in therapy.
Amy Harper   +2 more
doaj   +1 more source

Antiepileptic drugs reduce serum uric acid [PDF]

open access: yes, 1987
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab   +7 more
core   +1 more source

Continuous rate infusion of midazolam as emergent treatment for seizures in dogs

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Midazolam delivered by continuous rate infusion (CRI) might be effective in dogs with cluster seizures (CS) or status epilepticus (SE). Objective To describe the use and safety of midazolam CRI in dogs with CS or SE.
Kathryn Y. Bray   +4 more
doaj   +1 more source

Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]

open access: yes, 2014
IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve   +4 more
core   +1 more source

The Effects of Valproic Acid on Appetitive and Aversive Instrumental Learning in Adult Rats

open access: yesFrontiers in Behavioral Neuroscience, 2014
Antiepileptic medications are the frontline treatment for seizure conditions. However, these medications are not without cognitive side effects. Previously, our laboratory reported learning deficits in phenytoin and carbamazepine-treated rats.
John Joseph Orczyk   +4 more
doaj   +1 more source

Molecular Docking and Anticonvulsant Activity of Newly Synthesized Quinazoline Derivatives

open access: yesMolecules, 2017
A new series of quinazoline-4(3H)-ones are evaluated for anticonvulsant activity. After intraperitoneal (ip) injection to albino mice at a dose of 100 mg/kg body weight, synthesized quinazolin-4(3H)-ones (1–24) were examined in the maximal electroshock ...
Hatem A. Abuelizz   +6 more
semanticscholar   +1 more source

Female genital disorder as adverse symptom of lamotrigine treatment - A serotoninergic effect? [PDF]

open access: yes, 1998
The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake.
Amann, Benedikt   +2 more
core   +1 more source

Design, synthesis, and anticonvulsant effects evaluation of nonimidazole histamine H3 receptor antagonists/inverse agonists containing triazole moiety

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Histamine H3 receptors (H3R) antagonists/inverse agonists are becoming a promising therapeutic approach for epilepsy. In this article, novel nonimidazole H3R antagonists/inverse agonists have been designed and synthesised via hybriding the H3R ...
Mingxia Song   +5 more
doaj   +1 more source

Neuropharmacological Activity of the Acetonic Extract of Malpighia mexicana A. Juss. and Its Phytochemical Profile

open access: yesScientia Pharmaceutica, 2023
Mental and neurological disorders are conditions that affect thoughts, emotions, behavior, and relationships. Malpighia mexicana A. Juss. is a plant used in Mexican traditional medicine for the treatment of such disorders.
Dante Avilés-Montes   +11 more
doaj   +1 more source

Antiepileptic Drug Discovery and Development: What Have We Learned and Where Are We Going?

open access: yesPharmaceuticals, 2010
Current marketed antiepileptic drugs (AEDs) consist of a variety of structural classes with different mechanisms of action. These agents typically have non-overlapping efficacy and side-effect profiles presenting multiple treatment options for the ...
Jeffrey L. Krajewski, Aaron C. Gerlach
doaj   +1 more source

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