Results 21 to 30 of about 56,664 (214)

The Brugada Type 1 Electrocardiogram and Ventricular Tachycardia With High-Dose Amitriptyline

JACC: Case Reports, 2021
A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings.
Ji-Jian Chow, MRCP, Nandita Kaza, MBChB, Amanda Varnava, MD   +2 more
doaj  

Do antidepressants cure or create abnormal brain states? [PDF]

, 2006
Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental ...
Beasley, Beasley, Bourin, Breggin, Cohen, David Cohen, Delgado, Deptula, Dewa, Drevets, Dumont, Emrich, Fisher, Furlan, Goldberg, Harmer, Harmer, Herrmann, Hyman, Imlah, Joanna Moncrieff, Kennedy, Kirsch, Knegtering, Lacasse, Leo, Lowther, Malhi, Matsubara, Mayers, Meyer, Moncrieff, Moncrieff, Moncrieff, Moncrieff, Murphy, Niklson, Parsey, Patten, Pilgrim, Ramaekers, Ramaekers, Raptopoulos, Reivich, Rickels, Robbe, Robertson, Robinson, Rush, Sargent, Schildkraut, Stockmeier, Tranter, Tuma, Van Putten, Wingen   +55 more
core   +3 more sources

The impact of clustering binary data on relative risk towards a study of inferential methods [PDF]

arXiv, 2022
In epidemiological cohort studies, the relative risk (also known as risk ratio) is a major measure of association to summarize the results of two treatments or exposures. Generally, it measures the relative change in disease risk as a result of treatment application.
arxiv  

Exploratory Data Analysis of Electric Tricycle as Sustainable Public Transport Mode in General Santos City Using Logistic Regression [PDF]

arXiv, 2021
General Santos City, as the tuna capital of the Philippines, relies with the presence of tricycles in moving people and goods. Considered as a highly-urbanized city, General Santos City serves as vital link of the entire SOCKSARGEN region's economic activities.
arxiv  

Maximum values of the edge Mostar index in tricyclic graphs [PDF]

arXiv, 2023
For a graph $G$, the edge Mostar index of $G$ is the sum of $|m_u(e|G)-m_v(e|G)|$ over all edges $e=uv$ of $G$, where $m_u(e|G)$ denotes the number of edges of $G$ that have a smaller distance in $G$ to $u$ than to $v$, and analogously for $m_v(e|G)$.
arxiv  

PET studies of the serotonin system in major depression and its treatment [PDF]

, 2014
The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants.
Tiger, Mikael
core   +1 more source

Efficacy of Antidepressants in Management of Depressive Symptoms in Dementia: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Journal of Psychiatry Spectrum
Background: Dementia is associated with a complex array of neuropsychiatric manifestations which require consideration as they worsen the course of illness, especially in neurodegenerative etiologies.
R. Shantheri Pai, I. M. Shashikala, P. Hasitha Sudhakar   +2 more
doaj   +1 more source

The Potent And Selective α4β2*/α6*-Nicotinic Acetylcholine Receptor Partial Agonist 2-[5-[5-((S)Azetidin-2-Ylmethoxy)-3-Pyridinyl]-3-Isoxazolyl]Ethanol Demonstrates Antidepressive-Like Behavior In Animal Models And A Favorable Adme-Tox Profile [PDF]

, 2014
Preclinical and clinical studies demonstrated that the inhibition of cholinergic supersensitivity through nicotinic antagonists and partial agonists can be used successfully to treat depressed patients, especially those who are poor responders to ...
Brunner, Dani, Chang, Yong, Eaton, J. Brek, Hanania, Taleen, Kozikowski, Alan P., Li, Guan Nan, Liu, Qiang, Lukas, Ronald J., Sabath, Emily, van Breemen, Richard B., Whiteaker, Paul, Wu, Jie, Yu, Li Fang, Zhang, Han Kun   +13 more
core   +2 more sources

Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder [PDF]

, 2011
Background There is emerging evidence that antidepressants may be effective in preventing patients with non-specific and psychotic-like prodromal symptoms, defined as patients at ultra-high risk (UHR) of psychotic disorder, from transitioning to ...
Hashimoto, Kenji, Kanahara, Nobuhisa, Kikuchi, Shuichi, Masaomi, Iyo, Tadokoro, Shigenori   +4 more
core   +3 more sources

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source