Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]
, 2012 In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P +8 more
core +1 more source
PET studies of the serotonin system in major depression and its treatment [PDF]
, 2014 The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants.
Tiger, Mikael
core +1 more source
Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]
, 2002 Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B. +3 more
core +1 more source
Effectiveness of a recent topical sialogogue in the management of drug-induced xerostomia [PDF]
, 2011 Objectives: Use of certain drugs is the most common aetiology of xerostomia. Systemic sialogogues provide a longer effect than topic ones, but also induce relevant side effects. Topical sialogogues, as malic acid, allow a safe use as they
Aguilar Salvatierra, Antonio +3 more
core +1 more source
Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]
, 2004 Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C. +2 more
core +1 more source
Do antidepressants cure or create abnormal brain states? [PDF]
, 2006 Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental ...
Beasley +55 more
core +3 more sources
Use of antidepressants and the risk of myocardial infarction in middle-aged and older adults: A matched case-control study [PDF]
, 2016 Purpose: Antidepressants, specifically selective serotonin reuptake-inhibiting antidepressants (SSRIs), decrease platelet activation and aggregation in in vitro experiments and could therefore decrease the risk of myocardial infarction (MI).
Aarts, N. (Nikkie) +7 more
core +2 more sources
Automatic summarization of MEDLINE citations for evidence-based medical treatment: A topic-oriented evaluation [PDF]
, 2008 As the number of electronic biomedical textual resources increases, it becomes harder for physicians to find useful answers at the point of care. Information retrieval applications provide access to databases; however, little research has been done on ...
Fiszman, Marcelo +3 more
core +1 more source
Efeitos da fluoxetina sobre a ultraestrutura mitocondrial no ventrículo direito de ratos expostos ao estresse pelo frio [PDF]
, 2009 OBJECTIVE: To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress. METHODS: The experimental study procedures were performed in 250-300g male EPM-Wistar rats.
Abreu, Luiz Carlos de +7 more
core +4 more sources
The Global Landscape of Neuropsychiatric Prescribing Practices of Nurses: A Scoping Review
International Journal of Mental Health Nursing, Volume 34, Issue 4, July 2025.ABSTRACT Mental healthcare service access in South Africa is currently strained due to, among others, shortages of specialised mental healthcare professionals. The National Strategic Plan for HIV, TB and STIs (2023‐2028) recommends enabling nurses to diagnose, prescribe and dispense neuropsychiatric medication for promoting mental health services.
M. Naidoo, C. J. Filmalter, W. Cordier
wiley +1 more source