Results 21 to 30 of about 5,762 (194)

Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials? [PDF]

, 2008
Antidepressants, in particular newer agents, are among the most widely prescribed medications worldwide with annual sales of billions of dollars. The introduction of these agents in the market has passed through seemingly strict regulatory control.
John PA Ioannidis
core   +1 more source

Efficacy of Antidepressants in Management of Depressive Symptoms in Dementia: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Journal of Psychiatry Spectrum
Background: Dementia is associated with a complex array of neuropsychiatric manifestations which require consideration as they worsen the course of illness, especially in neurodegenerative etiologies.
R. Shantheri Pai, I. M. Shashikala, P. Hasitha Sudhakar   +2 more
doaj   +1 more source

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González, Yahira Guzman, Nadia Juliana Proaños, Rosa‐Helena Bustos, María Aconcha, Ivan Guerrero, Laura Alejandra Martinez, Michael Berk, Seetal Dodd   +8 more
wiley   +1 more source

Coronary artery disease and depression [PDF]

, 2017
Coronary artery disease (CAD) as well as depression are both highly prevalent diseases. Both cause a significant decrease in quality of life for the patient and impose a significant economic burden on society.
Langewitz, Wolf, Osterwalder, Remo H., Pfisterer, Matthias E., Zellweger, Michael J.   +3 more
core  

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen, Cille Bülow, Kim Dalhoff, David Peick Sonne   +3 more
wiley   +1 more source

Depression, antidepressant use, and breast cancer incidence: results from the E3N prospective cohort

Psychiatry and Clinical Neurosciences, Volume 79, Issue 9, Page 554-560, September 2025.
Aim Depression and antidepressant drugs may both impact breast cancer incidence, potentially in opposite directions. The few epidemiological studies attempting to disentangle their effects have been inconclusive. We aimed to assess within the same prospective cohort the association between depression, antidepressant use, and breast cancer risk, while ...
Romain Colle, Eric Deflesselle, Océane Mohamed, Bruno Falissard, Gianluca Severi, Agnès Fournier, Marie‐Christine Boutron‐Ruault, Emmanuelle Corruble   +7 more
wiley   +1 more source

利用三碘甲狀腺氨酸強化療法治療對於三環抗抑鬱藥物無效的濫用藥物病人 [PDF]

, 2001
We report on two substance misusers with depression resistant to tricyclic antidepressant treatment who responded to triiodothyronine augmentation.
Ho, TP, Kan, CK
core  

The Global Landscape of Neuropsychiatric Prescribing Practices of Nurses: A Scoping Review

International Journal of Mental Health Nursing, Volume 34, Issue 4, July 2025.
ABSTRACT Mental healthcare service access in South Africa is currently strained due to, among others, shortages of specialised mental healthcare professionals. The National Strategic Plan for HIV, TB and STIs (2023‐2028) recommends enabling nurses to diagnose, prescribe and dispense neuropsychiatric medication for promoting mental health services.
M. Naidoo, C. J. Filmalter, W. Cordier
wiley   +1 more source

Efeitos da fluoxetina sobre a ultraestrutura mitocondrial no ventrículo direito de ratos expostos ao estresse pelo frio [PDF]

, 2009
OBJECTIVE: To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress. METHODS: The experimental study procedures were performed in 250-300g male EPM-Wistar rats.
Abreu, Luiz Carlos de, Daud, Fernanda Vasquez, Ferreira Filho, Celso, Ferreira, Celso, Ferreira, Marcelo, Meneghini, Adriano, Murad, Neif, Valenti, Vitor Engrácia   +7 more
core   +4 more sources

The Study of Clinical Finding, Complications and Management of 24 Patients with Overused T.C.A.

پزشکی بالینی ابن سینا, 1999
The extensive use of tricyclic antidepression drugs, the approximation of the therapeutic levels of the drugs to toxic level and the availability of the drugs to depressed patients who have potentially the idea of committing suicide has made these drugs ...
Saeed Fallah, Ahmad Karimnia, Hadi Shaker   +2 more
doaj