Results 181 to 190 of about 1,132,887 (301)

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski, Klaudia Kolonko, Andromachi Giannopoulou, Beata Smela, Elżbieta Olewinska, Kristina Rosa Bolling, Jenifer Sassarini, Lee P. Shulman, Vikram Talaulikar   +8 more
wiley   +1 more source

Repurposing Antiepileptic Drugs for Cancer: A Promising Therapeutic Strategy. [PDF]

J Clin Med
Tarawneh N, Hussein SA, Abdalla S.
europepmc   +1 more source

Lithium Use in Pregnancy and the Risk of Spontaneous Preterm Birth: An Australian Statewide Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate whether lithium exposure in pregnancy is associated with spontaneous preterm birth, congenital malformations and abnormal fetal growth. Design Statewide retrospective cohort study. Setting Victoria, Australia. Population 867 454 births (2009–2020), including 234 (0.03%) exposed to lithium during pregnancy.
Alexandra Roddy Mitchell, Anthea Lindquist, Richard J. Hiscock, Anna Forsythe, Hannah Gordon, Caroline S. E. Homer, Natasha Pritchard, Jessica Atkinson, Susan P. Walker, Stephen Tong, Roxanne Hastie   +10 more
wiley   +1 more source

Evaluating the risk of osteopenia-related adverse events with antiepileptic drugs: a pharmacovigilance study based on the FAERS database. [PDF]

Front Pharmacol
Yang N, Han X, Hua H, Wang Y, Chen Y, Zhou Y, Feng H.   +6 more
europepmc   +1 more source

Diffuse cranial vault hyperostosis associated with long‐term antiepileptic therapy: Autopsy findings and differential diagnostic considerations

Journal of Forensic Sciences, EarlyView.
Abstract Diffuse cranial vault hyperostosis is an uncommon finding and may present a diagnostic challenge in clinical and forensic practice. We report the case of a 53‐year‐old woman with a long‐standing history of epilepsy treated with phenytoin and sodium valproate who collapsed at home suddenly and died despite resuscitative efforts.
Maria Piagkou, Athina Tousia, George Triantafyllou, Dimitrios Vlachodimitropoulos, Samer Al Besher, Panagiotis Manolarakis‐Papadopoulos, Alexandros Samolis, Stavroula Papadodima   +7 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development. [PDF]

Epilepsia
Bialer M, Johannessen Landmark C, Koepp MJ, Perucca E, Perucca P, Tomson T, White HS, Wirrell E.   +7 more
europepmc   +1 more source

GC/MS determination of gabapentin in human plasma and vitreous humor and its application to forensic samples

Journal of Forensic Sciences, EarlyView.
Abstract Gabapentin (GBP) is widely prescribed off‐label, and cases of misuse, abuse, self‐medication, and intentional self‐harm have been reported. This study aimed to develop and validate a simple GC‐MS method for the determination of GBP in plasma and vitreous humor (VH) and to explore the relationship between concentrations in both matrices in ...
Pamela Cabarcos‐Fernández, Inés Sánchez‐Sellero, Iván Álvarez‐Freire, María Jesús Tabernero‐Duque, Ana María Bermejo‐Barrera   +4 more
wiley   +1 more source

Placental transfer of third-generation antiepileptic drugs: in vivo lacosamide case study and in vitro investigation of transporter inhibition by lacosamide and perampanel. [PDF]

J Pharm Health Care Sci
Ueda A, Furugen A, Nishimura A, Umazume T, Aoyagi R, Okamoto K, Narumi K, Ueda H, Kobayashi M.   +8 more
europepmc   +1 more source

Contrast‐Induced Encephalopathy Following Elective Endovascular Aneurysm Treatment: The Role of Dual‐Energy CT and Correlation With Delphi Diagnostic Criteria

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Contrast‐induced encephalopathy (CIE) is an increasingly recognised neurological complication of iodinated contrast administration during neurointerventional procedures. Recently published 2025 Delphi‐based diagnostic criteria and management algorithms aim to standardise clinical practice; however, optimal neuroimaging strategies ...
Kaiwen Cabbabe, Charles Li, Shuangyue Tan, Lisa Broadley, Gerard S. Goh, Cameron Williams, Conor Houlihan, Helen Kavnoudias, Steve Bush, Carlos Chung, Winston Chong   +10 more
wiley   +1 more source

The use of antiepileptic drugs and their effects in pregnancy. [PDF]

Turk J Med Sci
Öztürk P, Çağlar AT.
europepmc   +1 more source