Results 11 to 20 of about 37,620 (268)
Teratogenicity of Antiepileptic Drugs
Clinical Psychopharmacology and Neuroscience, 2017 Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is to examine teratogenic effects of AED and the correlation between these malformations and AED in single or multiple pregnancies.This is a retrospective study of ...
Güveli, Betül Tekin +12 more
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Therapeutic drug monitoring – antiepileptic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Aims To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods The review is based on literature data and observations from clinical practice.
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Antiepileptic drug-induced psychosis associated with MTHFR C677T: a case report
Journal of Medical Case Reports, 2019 Background Various antiepileptic drugs can potentially cause psychiatric side effects in patients with epilepsy, but the precise mechanism of these actions remains unknown.
Masaru Shimura +6 more
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Teratogenic Effects of Antiepileptic Drugs
Pediatric Neurology Briefs, 1997 Data from 5 prospective European studies totaling 1,221 children exposed to antiepileptic drugs (AED) during pregnancy and 158 children of unexposed control pregnancies were analyzed to quantify the risk of major congenital malformations (MCM) and are ...
J Gordon Millichap
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Seizure Recurrence in Children after Stopping Antiepileptic Medication: 5-Year Follow-Up
Pediatrics and Neonatology, 2017 We wanted to identify in children with epilepsy the factors associated with seizure control and recurrence after a 2-year remission. Methods: We did a 5-year follow-up of epileptic children whose antiepileptic medication had been stopped.
Inn-Chi Lee +2 more
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Teratogenic Potential of Antiepileptic Drugs
Pediatric Neurology Briefs, 2000 The effect of antiepileptic drugs on intrauterine growth is reviewed from the Center for Human Molecular Genetics, Nebraska, and the University of Newcastle upon Tyne, UK.
J Gordon Millichap
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Established antiepileptic drugs
Seizure, 1997 Despite the recent entry into the market-place of a range of new pharmacological treatments for epilepsy, most patients still receive the standard antiepileptic drugs. This review considers the clinical place and practical use of these agents. Detailed consideration is given to carbamazepine, phenytoin, sodium valproate, phenobarbital and ethosuximide,
Brodie, Martin J., Dichter, Marc A.
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Rational Polytherapy with Antiepileptic Drugs
Pharmaceuticals, 2010 Approximately 30–40% of patients do not achieve seizure control with a single antiepileptic drug (AED). With the advent of multiple AEDs in the past 15 years, rational polytherapy, the goal of finding combinations of AEDs that have favorable ...
Jong Woo Lee, Barbara Dworetzky
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Current Therapeutic Research, 2020 : Background: Antiepileptic drugs are among the leading causes of drug-induced liver injury (DILI). Due to critical illness, children admitted to intensive care units are more prone to DILI.
Kannan Sridharan, MD, DM +3 more
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Antiepileptic Drugs and Thyroid Function
Pediatric Neurology Briefs, 2004 Thyroid function in 78 girls and female adolescents (aged 8-18 years) during pubertal development was evaluated while taking carbamazepine (CBZ), oxcarbazepine (OXC), or valproate (VPA) monotherapy for epilepsy and after withdrawal of antiepileptic drugs,
J Gordon Millichap
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