Results 31 to 40 of about 1,132,887 (301)

Drug-Induced Liver Injury in Critically Ill Children Taking Antiepileptic Drugs: A Retrospective Study

Current Therapeutic Research, 2020
: Background: Antiepileptic drugs are among the leading causes of drug-induced liver injury (DILI). Due to critical illness, children admitted to intensive care units are more prone to DILI.
Kannan Sridharan, MD, DM, Amal Al Daylami, MRCP, Reema Ajjawi, MD, Husain A.M. Al Ajooz, MD   +3 more
doaj   +1 more source

Antiepileptic Drugs and Visual Function

, 2007
Antiepileptic drugs are known to result in visual disturbances. A number of antiepileptic drugs have recently been reported to result in various abnormalities of vision, particularly deficiencies in visual fields and color vision.
Verrotti, Alberto, Franzoni, Emilio, Manco, Rossella, Matricardi, Sara, Chiarelli, Francesco   +4 more
core   +2 more sources

Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis. [PDF]

PLoS ONE, 2015
Encephalitis presents with seizures in the acute phase and increases the risk of late unprovoked seizures and epilepsy. This study aimed to evaluate the effect of antiepileptic drugs in pediatric patients with acute seizures due to encephalitis and ...
Kuang-Lin Lin, Jainn-Jim Lin, Shao-Hsuan Hsia, Min-Liang Chou, Po-Cheng Hung, Huei-Shyong Wang, CHEESE Study Group   +6 more
doaj   +1 more source

Pharmacogenetics and Antiepileptic Drugs [PDF]

Epilepsia, 2001
Summary:Responses among patients to antiepileptic drugs (AEDs) may be highly variable, with respect to both drug efficacy and safety. Pharmacogenetics addresses the genetic component of such patient variability. Differential response to phenytoin, for example, is related to interindividual genetic differences in the metabolic enzyme CYP2C9, and to a ...
openaire   +2 more sources

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

New data-driven method to predict the therapeutic indication of redeemed prescriptions in secondary data sources: a case study on antiseizure medications users aged ≥65 identified in Danish registries

BMJ Open
Objectives We aimed to develop a new data-driven method to predict the therapeutic indication of redeemed prescriptions in secondary data sources using antiepileptic drugs among individuals aged ≥65 identified in Danish registries.Design This was an ...
Kristian Kragholm, Carla Carnovale, Emilio Clementi, Maurizio Sessa, Israa Mahmoud, Vera Battini   +5 more
doaj   +1 more source

Challenges in the Treatment of Epilepsy [PDF]

Journal of Kerman University of Medical Sciences, 2012
Epilepsy is one of the most important diseases of nervous system that involves 0.5-1% of the population. In spite of new developments in antiepileptic drugs, between 20-30% of epileptic patients can not be controlled and even those who are controlled ...
H.A Ebrahimi
doaj  

Teratogenic Effects of Antiepileptic Drugs

Pediatric Neurology Briefs, 1997
Data from 5 prospective European studies totaling 1,221 children exposed to antiepileptic drugs (AED) during pregnancy and 158 children of unexposed control pregnancies were analyzed to quantify the risk of major congenital malformations (MCM) and are ...
J Gordon Millichap
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Hormonal Contraception, Seizures and Antiepileptic Drugs

, 2018
Contraception is an important consideration for women with epilepsy. The pharmacokinetic interactions between antiepileptic drugs and oral contraceptives are biderectional.
Dilek ATAKLI, Dilek Ataklı
core   +1 more source